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Scientific paper - Original scientific paper
Quantitative analysis of troponin I serum values in patients with acute cholecystitis
Collegium Antropologicum, 36 (2012), 1; 145-150. urn:nbn:hr:105:767004
Babić, Žarko; Bogdanović, Zoran; Dorosulić, Zdravko; Basha, Merita; Krznarić, Željko; Sjekavica, Ivo; Kujundžić, Milan; Tadić, Mario; Banić, Marko; Jagić, Vjekoslav; Marušić, Marinko

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Babić, Ž., Bogdanović, Z., Dorosulić, Z., Basha, M., Krznarić, Ž., Sjekavica, I. ... Marušić, M. (2012). Quantitative analysis of troponin I serum values in patients with acute cholecystitis . Collegium Antropologicum, 36. (1), 145-150. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:767004

Babić, Žarko, et al. "Quantitative analysis of troponin I serum values in patients with acute cholecystitis ." Collegium Antropologicum, vol. 36, no. 1, 2012, pp. 145-150. https://urn.nsk.hr/urn:nbn:hr:105:767004

Babić, Žarko, Zoran Bogdanović, Zdravko Dorosulić, Merita Basha, Željko Krznarić, Ivo Sjekavica, Milan Kujundžić, et al. "Quantitative analysis of troponin I serum values in patients with acute cholecystitis ." Collegium Antropologicum 36, no. 1 (2012): 145-150. https://urn.nsk.hr/urn:nbn:hr:105:767004

Babić, Ž., et al. (2012) 'Quantitative analysis of troponin I serum values in patients with acute cholecystitis ', Collegium Antropologicum, 36(1), pp. 145-150. Available at: https://urn.nsk.hr/urn:nbn:hr:105:767004 (Accessed 27 December 2024)

Babić Ž, Bogdanović Z, Dorosulić Z, Basha M, Krznarić Ž, Sjekavica I, and sur.. Quantitative analysis of troponin I serum values in patients with acute cholecystitis . Collegium Antropologicum [Internet]. 2012 March [cited 2024 December 27];36(1):145-150. Available at: https://urn.nsk.hr/urn:nbn:hr:105:767004

Ž. Babić, et al., "Quantitative analysis of troponin I serum values in patients with acute cholecystitis ", Collegium Antropologicum, vol. 36, no. 1, pp. 145-150, March 2012. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:767004. [Accessed: 27 December 2024]

Metadata
Title (english)Quantitative analysis of troponin I serum values in patients with acute cholecystitis
Title (croatian)Kvantitativna analiza serumskog troponina i u bolesnika s akutnom upalom žučnjaka
AuthorŽarko Babić
AuthorZoran Bogdanović
AuthorZdravko Dorosulić
AuthorMerita Basha
AuthorŽeljko Krznarić
AuthorIvo Sjekavica
AuthorMilan Kujundžić
AuthorMario Tadić
AuthorMarko Banić
AuthorVjekoslav Jagić
AuthorMarinko Marušić
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The diagnosis and staging of acute cholecystitis, upon a lot of diagnostic methods and some scoring systems, is still a great clinical problem. The aim of the study was to investigate if serum Troponin I is elevated in patients with acute cholecystitis. Following informed consent, 65 patients with clinical and laboratory signs of acute cholecystitis were enrolled. All patients had measured serum Troponin I level and an abdominal ultrasound was done before definitive treatment was performed. Increased serum Troponin I level was found in most patients with severe form of acute cholecystitis (p < 0.00001). It reached sensitivity of 94.5% and specificity of 57.1% of this test. In multiple regression analysis Troponin I significantly correlated (p < 0.05) with the serum aspartate aminotransferase (r = 0.27), gamma-glutamyl transferase (r = 0.25) and gallbladder wall (> 6 mm) thickness (r = 0.58). Our study confirms that in most patients with severe and acute cholecystitis, serum Troponin I is increased. Troponin I level is in a lower range than it would be in patients with cardiac muscle damage or necrosis. Measuring serum Troponin I is a fast, reliable and widely performed test that could, with other routinely measured parameters, help in early diagnosis of the severe form of acute cholecystitis.
Abstract (croatian)
Dijagnozu i stupnjevanje akutne upale žučnjaka i dalje je, unatoč brojnim dijagnostičkim metodama, ostao težak zadatak. Cilj ovog rada bio je istražiti ulogu povišenih serumskih vrijednosti Troponina I u bolesnika s akutnim kolecistitisom. Nakon informiranog pristanka u studiju smo uključili 65 bolesnika s kliničkim i laboratorijskim znakovima akutne upale žučnjaka. Svim bolesnicima je mjerena razina serumskog Troponina I te im je učinjen i transabdominalni ultrazvuk prije početka liječenja. U većine bolesnika s teškim oblikom akute upale žučnjaka nađene su povišene vrijednosti Troponina I (p<0,00001). Postigli smo osjetljivost testa od 94,5% i specifičnost testa od 57,1%. Testom multiple regresije statistički značajnija korelacija (p<0,05) postignuta je za Troponin I, za serumsku aspart aminotransferazu (r=0,27), gamaglutamil transferazu (r=0,25) i za debljinu stjenke žučnjaka (>6 mm) (r=0,58). Naša studija potvrđuje da je većina bolesnika s teškim oblikom akutne upale žučnjaka imala povišene vrijednosti Troponina, ali u vrijednostima koje nisu karakteristične za oštećenje ili nekrozu srčanog mišića. Mjerenje Troponina I brza je i široko primjenjiva metoda koja uz ostale rutinske parametre može pomoći u dijagnostici i stupnjevanju teških oblika akutne upale žučnjaka.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium Antropologicum
Numberingvol. 36, no. 1, pp. 145-150
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:767004
Publication2012-03
Document URLhttps://hrcak.srce.hr/78804
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-27 19:28:29