prikaz prve stranice dokumenta Incidence and mortality trends of leukemia and lymphoma in Croatia, 1988-2009
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Scientific paper - Original scientific paper
Incidence and mortality trends of leukemia and lymphoma in Croatia, 1988-2009
Croatian Medical Journal, 53 (2012), 2; 115-123. https://doi.org/doi: 10.3325/cmj.2012.53.115
Novak, Ina; Jakšić, Ozren; Kuliš, Tomislav; Batinjan, Katarina; Znaor, Ariana

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Novak, I., Jakšić, O., Kuliš, T., Batinjan, K. & Znaor, A. (2012). Incidence and mortality trends of leukemia and lymphoma in Croatia, 1988-2009. Croatian Medical Journal, 53. (2), 115-123. doi: doi: 10.3325/cmj.2012.53.115

Novak, Ina, et al. "Incidence and mortality trends of leukemia and lymphoma in Croatia, 1988-2009." Croatian Medical Journal, vol. 53, no. 2, 2012, pp. 115-123. https://doi.org/doi: 10.3325/cmj.2012.53.115

Novak, Ina, Ozren Jakšić, Tomislav Kuliš, Katarina Batinjan and Ariana Znaor. "Incidence and mortality trends of leukemia and lymphoma in Croatia, 1988-2009." Croatian Medical Journal 53, no. 2 (2012): 115-123. https://doi.org/doi: 10.3325/cmj.2012.53.115

Novak, I., et al. (2012) 'Incidence and mortality trends of leukemia and lymphoma in Croatia, 1988-2009', Croatian Medical Journal, 53(2), pp. 115-123. doi: doi: 10.3325/cmj.2012.53.115

Novak I, Jakšić O, Kuliš T, Batinjan K, Znaor A. Incidence and mortality trends of leukemia and lymphoma in Croatia, 1988-2009. Croatian Medical Journal [Internet]. 2012 April [cited 2024 December 28];53(2):115-123. doi: doi: 10.3325/cmj.2012.53.115

I. Novak, O. Jakšić, T. Kuliš, K. Batinjan and A. Znaor, "Incidence and mortality trends of leukemia and lymphoma in Croatia, 1988-2009", Croatian Medical Journal, vol. 53, no. 2, pp. 115-123, April 2012. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:506511. [Accessed: 28 December 2024]

Metadata
Title (english)Incidence and mortality trends of leukemia and lymphoma in Croatia, 1988-2009
AuthorIna Novak
AuthorOzren Jakšić
AuthorTomislav Kuliš
AuthorKatarina Batinjan
AuthorAriana Znaor
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
AIM: To investigate the time trends of leukemia and lymphoma in Croatia from 1988-2009, compare them with trends in other populations, and identify possible changes. ----- METHODS: The data sources were the Croatian National Cancer Registry for incidence data, Croatian Bureau of Statistics for the numbers of deaths, and United Nations population estimates. Joinpoint regression analysis using the age-standardized rates was used to analyze incidence and mortality trends. ----- RESULTS: Acute lymphoblastic leukemia and chronic lymphocytic leukemia incidence did not significantly change. Acute myeloid leukemia incidence significantly increased in women, with estimated annual percentage change (EAPC) of 2.6% during the whole period, and in men since 1998, with EAPC of 3.2%. Chronic myeloid leukemia incidence significantly decreased in women (EAPC -3.7%) and remained stable in men. Mortality rates were stable for both lymphoid and myeloid leukemia in both sexes. Hodgkin lymphoma non-significantly increased in incidence and significantly decreased in mortality (EAPCs of -5.6% in men and -3.7% in women). Non-Hodgkin lymphoma significantly increased in incidence in women (EAPC 3.2%) and non-significantly in men and in mortality in both men (EAPC 1.6%) and women (EAPC 1.8%). ----- CONCLUSION: While Croatia had similar leukemia and lymphoma incidence trends as the other countries, the mortality trends were less favorable than in Western Europe. The lack of declines of leukemia incidence and non-Hodgkin lymphoma mortality could be attributed to late introduction of optimal therapies. As currently the most up-to-date diagnostics and treatments are available and covered by health insurance, we expect more favorable trends in the future.
Abstract (croatian)
Trendovi incidencije i mortaliteta od leukemija i limfoma u Hrvatskoj, 1988.-2009. ----- Cilj Istražiti trendove incidencije i mortaliteta od leukemija i limfoma u Hrvatskoj, 1988.-2009., usporediti ih s trendovima u ostalim populacijama, i identificirati promjene u trendovima. ----- Postupci Podatke o incidenciji prikupili smo iz Hrvatskog registra za rak, podatke o mortalitetu iz Hrvatskog zavoda za statistiku, a koristili smo i populacijske procjene Ujedinjenih naroda. Kako bi analizirali trendove incidencije i mortaliteta proveli smo regresijsku analizu uz pomoć točaka spajanja (engl, joinpoint regression analysis) koristeći stope standardizirane po dobi. ----- Rezultati Incidencija akutne limfatične leukemije i kronične limfocitne leukemije nije se značajno promijenila. Incidencija akutne mijeloidne leukemije značajno je porasla kod žena, s procijenjenim godišnjim postotkom promjene (engl, EAPC) od 2,6% za vrijeme cijelog razdoblja, i kod muškaraca od 1998., s EAPC-om od 3,2%. Incidencija kronične mijeloidne leukemije značajno se smanjila kod žena (EAPC -3,7%) ali je ostala stabilna u muškaraca. Stope mortaliteta ostale su stabilne za limfatičnu i mijeloidnu leukemiju kod oba spola. Hodgkinov limfom imao je porast incidencije koji nije bio značajan, i smanjenje mortaliteta koje je bilo značajno (EAPC od -5,6% kod muškaraca i -3.7% kod žena). Ne-Hodgkinov limfom imao je značajan porast incidencije kod žena (EAPC 3,2%) i ne-značajan kod muškaraca, i porast mortaliteta i kod muškaraca (EAPC 1,6%) i kod žena (EAPC 1,8%). ----- Zaključak Iako je Hrvatska imala slične trendove incidencije leukemija i limfoma kao i ostale europske države, trendovi mortaliteta bili su nepovoljniji nego u zapadno-europskim državama. Izostanak pada mortaliteta od leukemije ne-Hodgkinovog limfoma mogao bi se pripisati kasnom uvođenju najboljih načina liječenja. S obzirom da su trenutno ipak dostupni najnoviji načini dijagnostike i liječenja, u budućnosti očekujemo povoljnije trendove.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatian Medical Journal
Numberingvol. 53, no. 2, pp. 115-123
p-ISSN0353-9504
DOIhttps://doi.org/doi: 10.3325/cmj.2012.53.115
URN:NBNurn:nbn:hr:105:506511
Publication2012-04
Document URLhttp://www.cmj.hr/2012/53/2/22522989.htm
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-27 19:34:38