prikaz prve stranice dokumenta New insight into the role of NT-proBNP in alcoholic liver cirrhosis as a noninvasive marker of esophageal varices
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Scientific paper - Original scientific paper
New insight into the role of NT-proBNP in alcoholic liver cirrhosis as a noninvasive marker of esophageal varices
Croatian Medical Journal, 53 (2012), 4; 374-378. https://doi.org/10.3325/cmj.2012.53.374
Ljubičić, Neven; Gomerčić, Marija; Zekanović, Dražen; Bodrožić-Džakić, Tomislava; Đuzel, Ana

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Ljubičić, N., Gomerčić, M., Zekanović, D., Bodrožić Džakić, T. & Đuzel, A. (2012). New insight into the role of NT-proBNP in alcoholic liver cirrhosis as a noninvasive marker of esophageal varices. Croatian Medical Journal, 53. (4), 374-378. doi: 10.3325/cmj.2012.53.374

Ljubičić, Neven, et al. "New insight into the role of NT-proBNP in alcoholic liver cirrhosis as a noninvasive marker of esophageal varices." Croatian Medical Journal, vol. 53, no. 4, 2012, pp. 374-378. https://doi.org/10.3325/cmj.2012.53.374

Ljubičić, Neven, Marija Gomerčić, Dražen Zekanović, Tomislava Bodrožić Džakić and Ana Đuzel. "New insight into the role of NT-proBNP in alcoholic liver cirrhosis as a noninvasive marker of esophageal varices." Croatian Medical Journal 53, no. 4 (2012): 374-378. https://doi.org/10.3325/cmj.2012.53.374

Ljubičić, N., et al. (2012) 'New insight into the role of NT-proBNP in alcoholic liver cirrhosis as a noninvasive marker of esophageal varices', Croatian Medical Journal, 53(4), pp. 374-378. doi: 10.3325/cmj.2012.53.374

Ljubičić N, Gomerčić M, Zekanović D, Bodrožić Džakić T, Đuzel A. New insight into the role of NT-proBNP in alcoholic liver cirrhosis as a noninvasive marker of esophageal varices. Croatian Medical Journal [Internet]. 2012 August [cited 2024 April 27];53(4):374-378. doi: 10.3325/cmj.2012.53.374

N. Ljubičić, M. Gomerčić, D. Zekanović, T. Bodrožić Džakić and A. Đuzel, "New insight into the role of NT-proBNP in alcoholic liver cirrhosis as a noninvasive marker of esophageal varices", Croatian Medical Journal, vol. 53, no. 4, pp. 374-378, August 2012. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:314283. [Accessed: 27 April 2024]

Metadata
Title (english)New insight into the role of NT-proBNP in alcoholic liver cirrhosis as a noninvasive marker of esophageal varices
AuthorNeven Ljubičić
AuthorMarija Gomerčić
AuthorDražen Zekanović
AuthorTomislava Bodrožić-Džakić
AuthorAna Đuzel
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
AIM: To investigate the association between plasma concentrations of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and formation of esophageal varices. ----- METHODS: Thirty-five patients with alcoholic cirrhosis were divided into three groups according to the Child-Pugh classification: grade A (n=11, 32%), B (n=12, 34%), and C (n=12, 34%). System hemodynamic parameters were measured using sphygmomanometry, electrocardiography, and echocardiography. NT-proBNP was analyzed by using an electrochemiluminiscence sandwich immunoassay. ----- RESULTS: The presence of esophageal varices was associated with a higher serum NT-proBNP level, with a cut-off value of <101 pg/mL (sensitivity, 87.60% and specificity, 72.73%; P<0.001). ----- CONCLUSIONS: NT-proBNP was found to be a marker of the presence of esophageal varices, but not a marker of progression of liver cirrhosis. In cirrhotic patients, NT-proBNP value <101 pg/mL was shown to be a valuable noninvasive parameter in predicting the presence of varices.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatian Medical Journal
Numberingvol. 53, no. 4, pp. 374-378
p-ISSN0353-9504
DOIhttps://doi.org/10.3325/cmj.2012.53.374
URN:NBNurn:nbn:hr:105:314283
Publication2012-08
Document URLhttp://www.cmj.hr/2012/53/4/22911531.htm
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-27 19:36:34