prikaz prve stranice dokumenta Significance of clinical stage, extent of surgery and outcome in cutaneous squamous cell carcinoma of the head and neck
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Scientific paper - Original scientific paper
Significance of clinical stage, extent of surgery and outcome in cutaneous squamous cell carcinoma of the head and neck
International Journal of Oral and Maxillofacial Surgery, 42 (2013), 1; 82-88. https://doi.org/10.1016/j.ijom.2012.10.007
Košec, Andro; Svetina, Lucija; Lukšić, Ivica

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Košec, A., Svetina, L. & Lukšić, I. (2013). Significance of clinical stage, extent of surgery and outcome in cutaneous squamous cell carcinoma of the head and neck. International Journal of Oral and Maxillofacial Surgery, 42. (1), 82-88. doi: 10.1016/j.ijom.2012.10.007

Košec, Andro, et al. "Significance of clinical stage, extent of surgery and outcome in cutaneous squamous cell carcinoma of the head and neck." International Journal of Oral and Maxillofacial Surgery, vol. 42, no. 1, 2013, pp. 82-88. https://doi.org/10.1016/j.ijom.2012.10.007

Košec, Andro, Lucija Svetina and Ivica Lukšić. "Significance of clinical stage, extent of surgery and outcome in cutaneous squamous cell carcinoma of the head and neck." International Journal of Oral and Maxillofacial Surgery 42, no. 1 (2013): 82-88. https://doi.org/10.1016/j.ijom.2012.10.007

Košec, A., Svetina, L. and Lukšić, I. (2013) 'Significance of clinical stage, extent of surgery and outcome in cutaneous squamous cell carcinoma of the head and neck', International Journal of Oral and Maxillofacial Surgery, 42(1), pp. 82-88. doi: 10.1016/j.ijom.2012.10.007

Košec A, Svetina L, Lukšić I. Significance of clinical stage, extent of surgery and outcome in cutaneous squamous cell carcinoma of the head and neck. International Journal of Oral and Maxillofacial Surgery [Internet]. 2013 January [cited 2024 November 23];42(1):82-88. doi: 10.1016/j.ijom.2012.10.007

A. Košec, L. Svetina and I. Lukšić, "Significance of clinical stage, extent of surgery and outcome in cutaneous squamous cell carcinoma of the head and neck", International Journal of Oral and Maxillofacial Surgery, vol. 42, no. 1, pp. 82-88, January 2013. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:178013. [Accessed: 23 November 2024]

Metadata
Title (english)Significance of clinical stage, extent of surgery and outcome in cutaneous squamous cell carcinoma of the head and neck
AuthorAndro Košec
AuthorLucija Svetina
AuthorIvica Lukšić
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The authors analyzed a new clinical staging system and its correlation with pathologic findings and patient survival. Patients were eligible for inclusion in this longitudinal retrospective cohort study if they had cutaneous squamous cell carcinoma on the head or neck, underwent surgery and had a minimum 3 year follow-up. The primary study variable was using a new clinical staging system. Secondary variables included the parotid as a predictor of metastatic spread to the lymphatic nodes in the neck and primary lesion histopathologic traits. The outcome variable was patient survival. Associations between variables were assessed using Fisher's exact test, Mann-Whitney test, Kaplan-Meier method and Mantel log-rank test. p<0.05 was considered significant. The sample comprised 103 patients. Regional metastatic disease was found in 24 patients. Histopathological analysis showed a higher frequency of neck metastatic disease if the parotid was positive for metastases (p=0.022). An extended staging system showed significant correlation between survival rate and substages (p=0.0105). Perineural invasion was a negative prognostic factor (p=0.0151). The results of this study suggest that combining curative parotidectomy and elective neck dissection could be beneficial in high risk patients. Both neck and parotid metastases should be included in the clinical and histological N classification.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleInternational Journal of Oral and Maxillofacial Surgery
Numberingvol. 42, no. 1, pp. 82-88
p-ISSN0901-5027
DOIhttps://doi.org/10.1016/j.ijom.2012.10.007
URN:NBNurn:nbn:hr:105:178013
Publication2013-01
Document URLhttps://doi.org/10.1016/j.ijom.2012.10.007
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-27 19:42:48