prikaz prve stranice dokumenta Antibiotic prescription rate for upper respiratory tract infections and risks for unnecessary prescription in Croatia
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Scientific paper - Original scientific paper
Antibiotic prescription rate for upper respiratory tract infections and risks for unnecessary prescription in Croatia
Collegium Antropologicum, 37 (2013), 2; 449-454. urn:nbn:hr:105:851145
Vrca Botica, Marija; Botica, Iva; Stamenić, Valerija; Tambić Andrašević, Arjana; Kern, Josipa; Stojanović Špehar, Stanislava

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Vrca Botica, M., Botica, I., Stamenić, V., Tambić Andrašević, A., Kern, J. & Stojanović Špehar, S. (2013). Antibiotic prescription rate for upper respiratory tract infections and risks for unnecessary prescription in Croatia . Collegium Antropologicum, 37. (2), 449-454. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:851145

Vrca Botica, Marija, et al. "Antibiotic prescription rate for upper respiratory tract infections and risks for unnecessary prescription in Croatia ." Collegium Antropologicum, vol. 37, no. 2, 2013, pp. 449-454. https://urn.nsk.hr/urn:nbn:hr:105:851145

Vrca Botica, Marija, Iva Botica, Valerija Stamenić, Arjana Tambić Andrašević, Josipa Kern and Stanislava Stojanović Špehar. "Antibiotic prescription rate for upper respiratory tract infections and risks for unnecessary prescription in Croatia ." Collegium Antropologicum 37, no. 2 (2013): 449-454. https://urn.nsk.hr/urn:nbn:hr:105:851145

Vrca Botica, M., et al. (2013) 'Antibiotic prescription rate for upper respiratory tract infections and risks for unnecessary prescription in Croatia ', Collegium Antropologicum, 37(2), pp. 449-454. Available at: https://urn.nsk.hr/urn:nbn:hr:105:851145 (Accessed 23 November 2024)

Vrca Botica M, Botica I, Stamenić V, Tambić Andrašević A, Kern J, Stojanović Špehar S. Antibiotic prescription rate for upper respiratory tract infections and risks for unnecessary prescription in Croatia . Collegium Antropologicum [Internet]. 2013 June [cited 2024 November 23];37(2):449-454. Available at: https://urn.nsk.hr/urn:nbn:hr:105:851145

M. Vrca Botica, I. Botica, V. Stamenić, A. Tambić Andrašević, J. Kern and S. Stojanović Špehar, "Antibiotic prescription rate for upper respiratory tract infections and risks for unnecessary prescription in Croatia ", Collegium Antropologicum, vol. 37, no. 2, pp. 449-454, June 2013. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:851145. [Accessed: 23 November 2024]

Metadata
Title (english)Antibiotic prescription rate for upper respiratory tract infections and risks for unnecessary prescription in Croatia
Title (croatian)Stopa propisivanja antibiotika za infekcije gornjeg dišnog trakta i rizici za nepotrebno propisivanje antibiotika u Hrvatskoj
AuthorMarija Vrca Botica
AuthorIva Botica
AuthorValerija Stamenić
AuthorArjana Tambić Andrašević
AuthorJosipa Kern
AuthorStanislava Stojanović Špehar
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Overprescribing of antibiotics in primary care has been recognized as public health problem. We investigated visits prescription rate of antibiotics to patients with upper respiratory tract infections (URTI) and unnecessary prescription for tonsillopharyngitis, in Croatia. In prospective observational study in November 2007. 25 GPs in Croatia recorded all patients' visits with URTI episode according ICPC-2. Clinical status of patients with tonsillopharyngitis were categorized according to Centor Criteria. 689 visits were analysed, 82% of visits were initial. Antibiotics were prescribed in 44.7% visits with URTI. There were no significant differences in antibiotic prescription rates regarding non-clinical factors. Antibiotics were prescribed to patients with tonsillopharyngitis in 62.2% visits. Unnecessary antibiotics were prescribed (Centor 1,2) in 49.6% visits with tonsillopharyngitis. Logistic regression analysis showed significant differences in unnecessary antibiotic prescription rates only with respect to the workday--Wednesday, CI (1.117-2.671), p = 0.0139. Leading antibiotic was amoxicillin + clavulonic acid, second was amoxicillin, the third were macrolides, the fourth was narrow spectrum penicillin and fifth were cephalosporins. This study shows over prescription for URTI. Unnecessary prescription for tonsillopharyngitis depend on non clinical factor--day of the week. This should be further explored and help to improved prescribe antibiotics.
Abstract (croatian)
Povećano propisivanje antibiotika u primarnoj zaštiti je prepoznato kao javno zdravstveni problem jer dovodi do povećanja rezistencije na antibiotike. Istražili smo propisivanje antibiotika po posjetu liječniku opće medicine u tijeku episode bolesti infekcija gornjeg respiratornog trakta (IGRT). Potom smo istražili nepotrebno propisivanje antibiotika pacijentima s tanzilofaringitisom u općoj medicini u Hrvatskoj. Studija je bila prospektivna, a provedena je u studenom 2007. godine. 25 liječnika opće medicine bilježili su sve posjete pacijenata s epizodom bolesti – IGRT prema ICPC-2. Klinički status pacijenata s epizodom tonzilofaringitisa određen je prema Centor Criteria klasifikaciji. Analizirano je 689 posjeta, od čega su 82% bili prvi posjeti. Antibiotici su propisani u 44,7% posjeta pacijentima sa IGRT. Nismo našli statistički značajnu razliku u propisivanju antibiotika prema nekliničkim čimbenicima za pacijente s IGRT. Antibiotici su propisani u 62,2% posjeta pacijentima sa tonzilofaringitisom. Za klinički status tonzilofaringitisa Centor 1 i 2, u 49,6% posjeta nepotrebno su propisani antibiotici. Logistička regresijska analiza pokazuje značajnost razlike za nepotrebno propisivanje za dane u tjednu – srijeda, CI (1,117–2,671), p=0,0139. Od propisanih antibiotika na prvom je mjestu amoksicilin + klavulonska kiselina, na drugom amoksicilin, na trećem mjestu su makrolidi, na četvrtom usko spektralni penicilini, a na petomu cefalosporini. Studija pokazuje povećano propisivanje antibiotika za IGRT u Hrvatskoj. Nepotrebno propisivanje za pacijente s tonzilofaringitisom ovisi o nekliničkim čimbenicima, dan u tjednu – srijeda. Nalaz će se istražiti u sljedećim studijama s ciljem smanjenja propisivanja antibiotika u općoj medicini.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium Antropologicum
Numberingvol. 37, no. 2, pp. 449-454
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:851145
Publication2013-06
Document URLhttps://hrcak.srce.hr/104481
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-27 19:50:07