prikaz prve stranice dokumenta Differences in oligoclonal bands and visual evoked potentials in patients with radiologically and clinically isolated syndrome
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Scientific paper - Original scientific paper
Differences in oligoclonal bands and visual evoked potentials in patients with radiologically and clinically isolated syndrome
Acta Neurologica Belgica, 113 (2013), 1; 13-17. https://doi.org/10.1007/s13760-012-0106-1
Gabelić, Tereza; Radmilović, Marin; Posavec, Vanja; Škvorc, Ana; Bošković, Mateja; Adamec, Ivan; Milivojević, Iva; Barun, Barbara; Habek, Mario

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Gabelić, T., Radmilović, M., Posavec, V., Škvorc, A., Bošković, M., Adamec, I. ... Habek, M. (2013). Differences in oligoclonal bands and visual evoked potentials in patients with radiologically and clinically isolated syndrome. Acta Neurologica Belgica, 113. (1), 13-17. doi: 10.1007/s13760-012-0106-1

Gabelić, Tereza, et al. "Differences in oligoclonal bands and visual evoked potentials in patients with radiologically and clinically isolated syndrome." Acta Neurologica Belgica, vol. 113, no. 1, 2013, pp. 13-17. https://doi.org/10.1007/s13760-012-0106-1

Gabelić, Tereza, Marin Radmilović, Vanja Posavec, Ana Škvorc, Mateja Bošković, Ivan Adamec, Iva Milivojević, Barbara Barun and Mario Habek. "Differences in oligoclonal bands and visual evoked potentials in patients with radiologically and clinically isolated syndrome." Acta Neurologica Belgica 113, no. 1 (2013): 13-17. https://doi.org/10.1007/s13760-012-0106-1

Gabelić, T., et al. (2013) 'Differences in oligoclonal bands and visual evoked potentials in patients with radiologically and clinically isolated syndrome', Acta Neurologica Belgica, 113(1), pp. 13-17. doi: 10.1007/s13760-012-0106-1

Gabelić T, Radmilović M, Posavec V, Škvorc A, Bošković M, Adamec I, and sur.. Differences in oligoclonal bands and visual evoked potentials in patients with radiologically and clinically isolated syndrome. Acta Neurologica Belgica [Internet]. 2013 March [cited 2024 April 29];113(1):13-17. doi: 10.1007/s13760-012-0106-1

T. Gabelić, et al., "Differences in oligoclonal bands and visual evoked potentials in patients with radiologically and clinically isolated syndrome", Acta Neurologica Belgica, vol. 113, no. 1, pp. 13-17, March 2013. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:073835. [Accessed: 29 April 2024]

Metadata
Title (english)Differences in oligoclonal bands and visual evoked potentials in patients with radiologically and clinically isolated syndrome
AuthorTereza Gabelić
AuthorMarin Radmilović
AuthorVanja Posavec
AuthorAna Škvorc
AuthorMateja Bošković
AuthorIvan Adamec
AuthorIva Milivojević
AuthorBarbara Barun
AuthorMario Habek
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The aim of this study was to determine the prevalence of cerebrospinal fluid (CSF) and visual evoked potentials (VEP) abnormalities, and ANA titers in patients with either clinically or radiologically isolated syndrome (CIS and RIS). We gathered records from 330 hospitalized patients diagnosed with CIS/RIS within a 3-year period. Symptoms, CSF findings, VEP and ANA titers were analyzed. Incomplete transverse myelitis was the presenting symptom in 32.7 %, optic neuritis in 22.7 %, brainstem/cerebellar symptoms in 19.4 %, hemispheral symptoms in 2.7 % and multifocal symptoms in 15.2 % of patients in the CIS cohort. We identified 24 (7.3 %) patients with atypical or no symptoms-RIS cohort. Positive oligoclonal bands (OCB) were found in 75.5 % patients. When we divided the patients into CIS and RIS groups, the presence of OCB was 82.4 and 44 %, respectively. VEP were performed in 87.3 % patients and prolonged latencies were found in 39.6 % of them (43.8 and 14.3 % in the CIS and RIS cohort, respectively). ANA were positive in 15.2 % (14.7 and 16 % in the CIS and RIS cohort, respectively) of patients. RIS patients had statistically significant lower percentages of positive OCB and positive VEP (P = 0.002 and 0.001, respectively). Detection of OCB and VEP still has an important role for satisfying the "no better explanation for the clinical presentation" criteria when presented with a patient with a first "radiological" demyelinating episode.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleActa Neurologica Belgica
Numberingvol. 113, no. 1, pp. 13-17
p-ISSN0300-9009
DOIhttps://doi.org/10.1007/s13760-012-0106-1
URN:NBNurn:nbn:hr:105:073835
Publication2013-03
Document URLhttps://doi.org/10.1007/s13760-012-0106-1
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-27 20:11:45