prikaz prve stranice dokumenta American ginseng extract (Panax quinquefolius L.) is safe in long-term use in type 2 diabetic patients
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Scientific paper - Original scientific paper
American ginseng extract (Panax quinquefolius L.) is safe in long-term use in type 2 diabetic patients
Evidence-Based Complementary and Alternative Medicine, 2014 (2014); 969168. https://doi.org/10.1155/2014/969168
Mucalo, Iva; Jovanovski, Elena; Vuksan, Vladimir; Božikov, Velimir; Romić, Željko; Rahelić, Dario

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Mucalo, I., Jovanovski, E., Vuksan, V., Božikov, V., Romić, Ž. & Rahelić, D. (2014). American ginseng extract (Panax quinquefolius L.) is safe in long-term use in type 2 diabetic patients. Evidence-Based Complementary and Alternative Medicine, 2014., 969168. doi: 10.1155/2014/969168

Mucalo, Iva, et al. "American ginseng extract (Panax quinquefolius L.) is safe in long-term use in type 2 diabetic patients." Evidence-Based Complementary and Alternative Medicine, vol. 2014, 2014, p. 969168. https://doi.org/10.1155/2014/969168

Mucalo, Iva, Elena Jovanovski, Vladimir Vuksan, Velimir Božikov, Željko Romić and Dario Rahelić. "American ginseng extract (Panax quinquefolius L.) is safe in long-term use in type 2 diabetic patients." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 969168. https://doi.org/10.1155/2014/969168

Mucalo, I., et al. (2014) 'American ginseng extract (Panax quinquefolius L.) is safe in long-term use in type 2 diabetic patients', Evidence-Based Complementary and Alternative Medicine, 2014, p. 969168. doi: 10.1155/2014/969168

Mucalo I, Jovanovski E, Vuksan V, Božikov V, Romić Ž, Rahelić D. American ginseng extract (Panax quinquefolius L.) is safe in long-term use in type 2 diabetic patients. Evidence-Based Complementary and Alternative Medicine [Internet]. 2014 [cited 2024 November 07];2014:969168. doi: 10.1155/2014/969168

I. Mucalo, E. Jovanovski, V. Vuksan, V. Božikov, Ž. Romić and D. Rahelić, "American ginseng extract (Panax quinquefolius L.) is safe in long-term use in type 2 diabetic patients", Evidence-Based Complementary and Alternative Medicine, vol. 2014, p. 969168, 2014. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:792643. [Accessed: 07 November 2024]

Metadata
Title (english)American ginseng extract (Panax quinquefolius L.) is safe in long-term use in type 2 diabetic patients
AuthorIva Mucalo
AuthorElena Jovanovski
AuthorVladimir Vuksan
AuthorVelimir Božikov
AuthorŽeljko Romić
AuthorDario Rahelić
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Aim. The objective of the present study was to test the safety of supplementation with the American ginseng (AG) interventional material as an adjunct to conventional therapy (diet and/or medications) in type 2 diabetes, using a double-blind, randomized, placebo-controlled, parallel design. ----- Methods. Each participant received either AG (10% ginsenosides) or placebo capsules (500 mg/meal = 3 g/day) for a period of 12 weeks. Outcomes included measures of safety including kidney function (urates and creatinine), liver function (AST and ALT), and haemostatic function (PV and INR). ----- Results. Seventy-four participants with well-controlled type 2 diabetes (sex: 28 M and 46 F, age: 63 ± 9.5, BMI: 32 ± 5, and HbA1c: 7 ± 1.3), randomized to either intervention (n = 35) or control (n = 39) group, completed the study. There was no change in any of the measures of safety between treatments from baseline. The number or severity of adverse events did not differ between the AG intervention and placebo. ----- Conclusion. Following 12 weeks of supplementation with AG, safety was not compromised in a high cardiovascular disease (CVD) risk population of patients with type 2 diabetes. This demonstrated that safety is noteworthy, as reviews have continuously warned of possible adverse effects of ginseng consumption.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleEvidence-Based Complementary and Alternative Medicine
Numberingvol. 2014, p. 969168
p-ISSN1741-427X
DOIhttps://doi.org/10.1155/2014/969168
URN:NBNurn:nbn:hr:105:792643
Publication2014
Document URLhttp://doi.org/10.1155/2014/969168
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 08:06:36