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Scientific paper - Case study
Familial adenomatous polyposis in three generations of a single family: a case study
Case Reports in Oncology, 7 (2014), 2; 349-356. https://doi.org/10.1159/000363221
Murgić, Jure; Kirac, Iva; Soldić, Željko; Tomas, Davor; Zovak, Mario; Bolanča, Ante; Plawski, Andrzej; Banasiewicz, Tomasz; Kusić, Zvonko

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Murgić, J., Kirac, I., Soldić, Ž., Tomas, D., Zovak, M., Bolanča, A. ... Kusić, Z. (2014). Familial adenomatous polyposis in three generations of a single family: a case study. Case Reports in Oncology, 7. (2), 349-356. doi: 10.1159/000363221

Murgić, Jure, et al. "Familial adenomatous polyposis in three generations of a single family: a case study." Case Reports in Oncology, vol. 7, no. 2, 2014, pp. 349-356. https://doi.org/10.1159/000363221

Murgić, Jure, Iva Kirac, Željko Soldić, Davor Tomas, Mario Zovak, Ante Bolanča, Andrzej Plawski, Tomasz Banasiewicz and Zvonko Kusić. "Familial adenomatous polyposis in three generations of a single family: a case study." Case Reports in Oncology 7, no. 2 (2014): 349-356. https://doi.org/10.1159/000363221

Murgić, J., et al. (2014) 'Familial adenomatous polyposis in three generations of a single family: a case study', Case Reports in Oncology, 7(2), pp. 349-356. doi: 10.1159/000363221

Murgić J, Kirac I, Soldić Ž, Tomas D, Zovak M, Bolanča A, and sur.. Familial adenomatous polyposis in three generations of a single family: a case study. Case Reports in Oncology [Internet]. 2014 May 28 [cited 2024 December 27];7(2):349-356. doi: 10.1159/000363221

J. Murgić, et al., "Familial adenomatous polyposis in three generations of a single family: a case study", Case Reports in Oncology, vol. 7, no. 2, pp. 349-356, May 2014. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:339713. [Accessed: 27 December 2024]

Metadata
Title (english)Familial adenomatous polyposis in three generations of a single family: a case study
AuthorJure Murgić
AuthorIva Kirac
AuthorŽeljko Soldić
AuthorDavor Tomas
AuthorMario Zovak
AuthorAnte Bolanča
AuthorAndrzej Plawski
AuthorTomasz Banasiewicz
AuthorZvonko Kusić
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
BACKGROUND: Familial adenomatous polyposis (FAP) is an autosomal dominantly inherited syndrome characterized by the development of numerous polyps in the colon and rectum. If left untreated, the affected patients inevitably develop colon cancer by the age of 40 years. A resection of the colon (colectomy) or of the colon and rectum (proctocolectomy) is needed to minimize the risk of cancer. ----- CASE PRESENTATION: We report a case of FAP through three generations of a single family, in which the grandmother and granddaughter underwent total colectomy with ileoanal anastomosis and did not develop colon cancer, while the son underwent subtotal colectomy with ileorectal anastomosis and developed recurrent rectal cancer. Data regarding timely surgery, surveillance, and chemoprevention are discussed. ----- CONCLUSION: The FAP phenotype determines the type of treatment. In severe polyposis, proctocolectomy with ileoanal anastomosis seems to be the optimal method for minimizing the risk of cancer development. This case report advocates complete rectal removal, especially in cases of poor patient compliance with colonoscopic surveillance.
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCase Reports in Oncology
Numberingvol. 7, no. 2, pp. 349-356
p-ISSN1662-6575
DOIhttps://doi.org/10.1159/000363221
URN:NBNurn:nbn:hr:105:339713
Publication2014-05-28
Document URLhttp://doi.org/10.1159/000363221
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 08:31:21