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Scientific paper - Review paper
Modulating composition and metabolic activity of the gut microbiota in IBD patients
International Journal of Molecular Sciences, 17 (2016), 4; 578. https://doi.org/10.3390/ijms17040578
Matijašić, Mario; Meštrović, Tomislav; Perić, Mihaela; Čipčić Paljetak, Hana; Panek, Marina; Vranešić Bender, Darija; Ljubas Kelečić, Dina; Krznarić, Željko; Verbanac, Donatella

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Matijašić, M., Meštrović, T., Perić, M., Čipčić Paljetak, H., Panek, M., Vranešić Bender, D. ... Verbanac, D. (2016). Modulating composition and metabolic activity of the gut microbiota in IBD patients. International Journal of Molecular Sciences, 17. (4), 578. doi: 10.3390/ijms17040578

Matijašić, Mario, et al. "Modulating composition and metabolic activity of the gut microbiota in IBD patients." International Journal of Molecular Sciences, vol. 17, no. 4, 2016, p. 578. https://doi.org/10.3390/ijms17040578

Matijašić, Mario, Tomislav Meštrović, Mihaela Perić, Hana Čipčić Paljetak, Marina Panek, Darija Vranešić Bender, Dina Ljubas Kelečić, Željko Krznarić and Donatella Verbanac. "Modulating composition and metabolic activity of the gut microbiota in IBD patients." International Journal of Molecular Sciences 17, no. 4 (2016): 578. https://doi.org/10.3390/ijms17040578

Matijašić, M., et al. (2016) 'Modulating composition and metabolic activity of the gut microbiota in IBD patients', International Journal of Molecular Sciences, 17(4), p. 578. doi: 10.3390/ijms17040578

Matijašić M, Meštrović T, Perić M, Čipčić Paljetak H, Panek M, Vranešić Bender D, and sur.. Modulating composition and metabolic activity of the gut microbiota in IBD patients. International Journal of Molecular Sciences [Internet]. 2016 April 19 [cited 2024 November 09];17(4):578. doi: 10.3390/ijms17040578

M. Matijašić, et al., "Modulating composition and metabolic activity of the gut microbiota in IBD patients", International Journal of Molecular Sciences, vol. 17, no. 4, p. 578, April 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:804194. [Accessed: 09 November 2024]

Metadata
Title (english)Modulating composition and metabolic activity of the gut microbiota in IBD patients
AuthorMario Matijašić
AuthorTomislav Meštrović
AuthorMihaela Perić
AuthorHana Čipčić Paljetak
AuthorMarina Panek
AuthorDarija Vranešić Bender
AuthorDina Ljubas Kelečić
AuthorŽeljko Krznarić
AuthorDonatella Verbanac
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The healthy intestine represents a remarkable interface where sterile host tissues come in contact with gut microbiota, in a balanced state of homeostasis. The imbalance of gut homeostasis is associated with the onset of many severe pathological conditions, such as inflammatory bowel disease (IBD), a chronic gastrointestinal disorder increasing in incidence and severely influencing affected individuals. Despite the recent development of next generation sequencing and bioinformatics, the current scientific knowledge of specific triggers and diagnostic markers to improve interventional approaches in IBD is still scarce. In this review we present and discuss currently available and emerging therapeutic options in modulating composition and metabolic activity of gut microbiota in patients affected by IBD. Therapeutic approaches at the microbiota level, such as dietary interventions alone or with probiotics, prebiotics and synbiotics, administration of antibiotics, performing fecal microbiota transplantation (FMT) and the use of nematodes, all represent a promising opportunities towards establishing and maintaining of well-being as well as improving underlying IBD symptoms.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleInternational Journal of Molecular Sciences
Numberingvol. 17, no. 4, p. 578
p-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms17040578
URN:NBNurn:nbn:hr:105:804194
Publication2016-04-19
Document URLhttp://doi.org/10.3390/ijms17040578
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 08:38:53