prikaz prve stranice dokumenta Methicillin-resistant S. aureus (MRSA), extended-spectrum (ESBL)- and plasmid-mediated AmpC ß-lactamase -producing Gram-negative bacteria associated with skin and soft tissue infections in hospital and community settings
  Download
PDF 549.17 KB
Scientific paper - Original scientific paper
Methicillin-resistant S. aureus (MRSA), extended-spectrum (ESBL)- and plasmid-mediated AmpC ß-lactamase -producing Gram-negative bacteria associated with skin and soft tissue infections in hospital and community settings
Medicinski glasnik, 12 (2015), 2; 157-168. https://doi.org/10.17392/816-15
Uzunović, Selma; Bedenić, Branka; Budimir, Ana; Ibrahimagić, Amir; Kamberović, Farah; Fiolić, Zlatko; Rijnders, Michelle I. A.; Stobberingh, Ellen E.

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Uzunović, S., Bedenić, B., Budimir, A., Ibrahimagić, A., Kamberović, F., Fiolić, Z. ... Stobberingh, E. E. (2015). Methicillin-resistant S. aureus (MRSA), extended-spectrum (ESBL)- and plasmid-mediated AmpC ß-lactamase -producing Gram-negative bacteria associated with skin and soft tissue infections in hospital and community settings. Medicinski glasnik, 12. (2), 157-168. doi: 10.17392/816-15

Uzunović, Selma, et al. "Methicillin-resistant S. aureus (MRSA), extended-spectrum (ESBL)- and plasmid-mediated AmpC ß-lactamase -producing Gram-negative bacteria associated with skin and soft tissue infections in hospital and community settings." Medicinski glasnik, vol. 12, no. 2, 2015, pp. 157-168. https://doi.org/10.17392/816-15

Uzunović, Selma, Branka Bedenić, Ana Budimir, Amir Ibrahimagić, Farah Kamberović, Zlatko Fiolić, Michelle I. A. Rijnders and Ellen E. Stobberingh. "Methicillin-resistant S. aureus (MRSA), extended-spectrum (ESBL)- and plasmid-mediated AmpC ß-lactamase -producing Gram-negative bacteria associated with skin and soft tissue infections in hospital and community settings." Medicinski glasnik 12, no. 2 (2015): 157-168. https://doi.org/10.17392/816-15

Uzunović, S., et al. (2015) 'Methicillin-resistant S. aureus (MRSA), extended-spectrum (ESBL)- and plasmid-mediated AmpC ß-lactamase -producing Gram-negative bacteria associated with skin and soft tissue infections in hospital and community settings', Medicinski glasnik, 12(2), pp. 157-168. doi: 10.17392/816-15

Uzunović S, Bedenić B, Budimir A, Ibrahimagić A, Kamberović F, Fiolić Z, and sur.. Methicillin-resistant S. aureus (MRSA), extended-spectrum (ESBL)- and plasmid-mediated AmpC ß-lactamase -producing Gram-negative bacteria associated with skin and soft tissue infections in hospital and community settings. Medicinski glasnik [Internet]. 2015 August [cited 2024 April 28];12(2):157-168. doi: 10.17392/816-15

S. Uzunović, et al., "Methicillin-resistant S. aureus (MRSA), extended-spectrum (ESBL)- and plasmid-mediated AmpC ß-lactamase -producing Gram-negative bacteria associated with skin and soft tissue infections in hospital and community settings", Medicinski glasnik, vol. 12, no. 2, pp. 157-168, August 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:313271. [Accessed: 28 April 2024]

Metadata
Title (english)Methicillin-resistant S. aureus (MRSA), extended-spectrum (ESBL)- and plasmid-mediated AmpC ß-lactamase -producing Gram-negative bacteria associated with skin and soft tissue infections in hospital and community settings
AuthorSelma Uzunović
AuthorBranka Bedenić
AuthorAna Budimir
AuthorAmir Ibrahimagić
AuthorFarah Kamberović
AuthorZlatko Fiolić
AuthorMichelle I. A. Rijnders
AuthorEllen E. Stobberingh
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
AIM To investigate the characteristics of meticillin-resistant S. aureus (MRSA), extended-spectrum (ESBL), and plasmid-mediated AmpC beta-lactamase producing Gram-negative bacteria causing skin and soft tissue infections (SSTIs) in hospital and outpatient settings of Zenica-Doboj Canton, Bosnia and Herzegovina. ----- METHODS Antibiotic susceptibility was determined by disc-diffusion and broth microdillution methods according to CLSI guidelines. MecA gene was detected by PCR, and genetic characterization of MRSA was performed using spa-typing and the algorithm based upon repeat patterns (BURP). Double-disk-synergy test was used to screen for ESBLs. PCR was used to detect blaESBL alleles. Genetic relatedness of the strains was tested by PFGE. ----- RESULTS Seventeen in-patients with MRSA, 13 with ESBL-producing Gram-negative bacteria and three patients co-infected with both, were detected. Five MRSA and 16 ESBL-producing Gram-negative bacteria were found in outpatient samples. Klebsiella spp. was isolated in 11 in- and seven outpatients. MLST CC152 was the most prevalent MRSA. Seven (38.9%) Klebsiella spp. yielded amplicons with primers specific for SHV, TEM-1 and CTX-M group 1 β-lactamases. Eight K. pneumonia (44.4%) and 16 (64%) MRSA (including the in- and outpatient) strains were clonally related. ----- CONCLUSION The presence of MRSA and ESBL-producing organisms causing SSTIs in the community poses a substantial concern, due to the high morbidity and mortality associated with possible consequent hospital infections.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicinski glasnik
Numberingvol. 12, no. 2, pp. 157-168
p-ISSN1840-2445
DOIhttps://doi.org/10.17392/816-15
URN:NBNurn:nbn:hr:105:313271
Publication2015-08
Document URLhttps://doi.org/10.17392/816-15
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 08:40:10