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Scientific paper - Original scientific paper
Which questionnaires should we use to evaluate quality of life in patients with chronic graft-vs-host disease?
Croatian Medical Journal, 57 (2016), 1; 6-15. https://doi.org/10.3325/cmj.2016.57.6
Perić, Zinaida; Desnica, Lana; Duraković, Nadira; Ostojić, Alen; Pulanić, Dražen; Serventi-Seiwerth, Ranka; Prenc, Ema; Basak, Grzegorz; Vrhovac, Radovan; Pavletic, Steven Z; Nemet, Damir

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Perić, Z., Desnica, L., Duraković, N., Ostojić, A., Pulanić, D., Serventi Seiwerth, R. ... Nemet, D. (2016). Which questionnaires should we use to evaluate quality of life in patients with chronic graft-vs-host disease?. Croatian Medical Journal, 57. (1), 6-15. doi: 10.3325/cmj.2016.57.6

Perić, Zinaida, et al. "Which questionnaires should we use to evaluate quality of life in patients with chronic graft-vs-host disease?." Croatian Medical Journal, vol. 57, no. 1, 2016, pp. 6-15. https://doi.org/10.3325/cmj.2016.57.6

Perić, Zinaida, Lana Desnica, Nadira Duraković, Alen Ostojić, Dražen Pulanić, Ranka Serventi Seiwerth, Ema Prenc, et al. "Which questionnaires should we use to evaluate quality of life in patients with chronic graft-vs-host disease?." Croatian Medical Journal 57, no. 1 (2016): 6-15. https://doi.org/10.3325/cmj.2016.57.6

Perić, Z., et al. (2016) 'Which questionnaires should we use to evaluate quality of life in patients with chronic graft-vs-host disease?', Croatian Medical Journal, 57(1), pp. 6-15. doi: 10.3325/cmj.2016.57.6

Perić Z, Desnica L, Duraković N, Ostojić A, Pulanić D, Serventi Seiwerth R, and sur.. Which questionnaires should we use to evaluate quality of life in patients with chronic graft-vs-host disease?. Croatian Medical Journal [Internet]. 2016 February [cited 2024 April 29];57(1):6-15. doi: 10.3325/cmj.2016.57.6

Z. Perić, et al., "Which questionnaires should we use to evaluate quality of life in patients with chronic graft-vs-host disease?", Croatian Medical Journal, vol. 57, no. 1, pp. 6-15, February 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:843086. [Accessed: 29 April 2024]

Metadata
Title (english)Which questionnaires should we use to evaluate quality of life in patients with chronic graft-vs-host disease?
AuthorZinaida Perić
AuthorLana Desnica
AuthorNadira Duraković
AuthorAlen Ostojić
AuthorDražen Pulanić
AuthorRanka Serventi-Seiwerth
AuthorEma Prenc
AuthorGrzegorz Basak
AuthorRadovan Vrhovac
AuthorSteven Z Pavletic
AuthorDamir Nemet
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
AIM: To investigate the ability of two standard quality of life (QOL) questionnaires - The Short Form (36-item) Health Survey (SF-36) and The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ C30) to evaluate QOL in patients with chronic graft-vs-host disease (cGVHD) graded according to National Institutes of Health (NIH) consensus criteria. ----- METHODS: In this cross-sectional study, QOL was assessed in patients who underwent allogeneic stem cell transplantation (allo-SCT) at the University Hospital Centre Zagreb and were alive and in complete remission for more than one year after allo-SCT. ----- RESULTS: The study included 58 patients, 38 patients with cGVHD and 20 controls, patients without cGVHD. Patients with cGVHD scored according to the NIH criteria had significantly lower scores of global health status and lower QOL on all SF-36 subscales and most of QLQ C30 functional subscales (P<0.050 for all comparisons). Furthermore, patients with active cGVHD had significantly lower QOL scores than patients with inactive cGVHD, and this difference was most evident in physical functioning subscale of SF-36 (P=0.0007) and social functioning subscale of QLQ C30 (P=0.009). ----- CONCLUSION: cGVHD scored according to the NIH criteria is correlated with patient-reported QOL, particularly in the physical domains as detected by SF-36. QLQ C30 questionnaire adds more information on social functioning and should be used as a valuable tool in the evaluation of social domains in cGVHD patients.
Abstract (croatian)
Koje upitnike trebamo koristiti za procjenu kvalitete života pacijenata s kroničnom bolešću presatka protiv primatelja? ----- Cilj: Istražiti može li se kvaliteta života pacijenata s kroničnom bolešću presatka protiv primatelja podijeljenih prema kriterijima Američkih instituta za zdravlje (prema engl. National Institutes of Health, NIH) procjenjivati uz pomoć dva standardna upitnika – Kratke zdravstvene ankete (prema engl. The Short Form Health Survey, SF-36) i Upitnika o kvaliteti života Europske organizacije za istraživanje i liječenje raka – Osnovni upitnik 30 (prema engl. The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30, EORTC QLQ C30). ----- Postupci: U ovom presječnom istraživanju, kvaliteta života procijenjena je kod pacijenata podvrgnutih alogenoj transplantaciji matičnih stanica u Kliničkom bolničkom centru "Zagreb" te su bili živi i u potpunoj remisiji više od godinu dana nakon transplantacije. ----- Rezultati: Istraživanje je uključilo 58 pacijenata, 38 pacijenata s kroničnom bolešću presatka protiv primatelja i 20 kontrolnih ispitanika. Pacijenti s kroničnom bolešću presatka protiv primatelja prema NIH kriterijima imali su značajno niži izračun ukupnog zdravstvenog statusa i nižu kvalitetu života na svim podljestvicama SF-36 upitnika i većini funkcionalnih podljestvica QLQ C30 upitnika (P<0,050 za sve usporedbe). Pacijenti s aktivnom bolešću imali su značajno niži izračun kvalitete života nego pacijenti s neaktivnom bolešću, a ova razlika bila je najuočljivija na podljestvici fizičkog funkcioniranja SF-36 upitnika (P= 0,0007) i na podljestvici socijalnog funkcioniranja QLQ C30 upitnika (P=0,009). ----- Zaključak: Kronična bolest presatka protiv primatelja stupnjevana prema NIH kriterijima korelirala je sa samoprocijenjenom kvalitetom života, posebice u fizičkim domenama koje ispituje SF-36. QLQ C30 upitnik pružio je dodatne informacije o socijalnom funkcioniranju pacijenata i pokazao se kao vrijedan alat za procjenu socijalne domene kod pacijenata s kroničnom bolešću presatka protiv primatelja.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleCroatian Medical Journal
Numberingvol. 57, no. 1, pp. 6-15
p-ISSN0353-9504
DOIhttps://doi.org/10.3325/cmj.2016.57.6
URN:NBNurn:nbn:hr:105:843086
Publication2016-02
Document URLhttps://doi.org/10.3325/cmj.2016.57.6
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 08:42:16