prikaz prve stranice dokumenta Combined ovulation triggering with GnRH agonist and hCG in IVF patients
  Download
PDF 380.35 KB
Scientific paper - Review paper
Combined ovulation triggering with GnRH agonist and hCG in IVF patients
Gynecological Endocrinology, 32 (2016), 11; 861-865. https://doi.org/10.1080/09513590.2016.1193141
Kasum, Miro; Kurdija, Kristijan; Orešković, Slavko; Čehić, Ermin; Pavičić-Baldani, Dinka; Škrgatić, Lana

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Kasum, M., Kurdija, K., Orešković, S., Čehić, E., Pavičić Baldani, D. & Škrgatić, L. (2016). Combined ovulation triggering with GnRH agonist and hCG in IVF patients. Gynecological Endocrinology, 32. (11), 861-865. doi: 10.1080/09513590.2016.1193141

Kasum, Miro, et al. "Combined ovulation triggering with GnRH agonist and hCG in IVF patients." Gynecological Endocrinology, vol. 32, no. 11, 2016, pp. 861-865. https://doi.org/10.1080/09513590.2016.1193141

Kasum, Miro, Kristijan Kurdija, Slavko Orešković, Ermin Čehić, Dinka Pavičić Baldani and Lana Škrgatić. "Combined ovulation triggering with GnRH agonist and hCG in IVF patients." Gynecological Endocrinology 32, no. 11 (2016): 861-865. https://doi.org/10.1080/09513590.2016.1193141

Kasum, M., et al. (2016) 'Combined ovulation triggering with GnRH agonist and hCG in IVF patients', Gynecological Endocrinology, 32(11), pp. 861-865. doi: 10.1080/09513590.2016.1193141

Kasum M, Kurdija K, Orešković S, Čehić E, Pavičić Baldani D, Škrgatić L. Combined ovulation triggering with GnRH agonist and hCG in IVF patients. Gynecological Endocrinology [Internet]. 2016 November [cited 2024 May 06];32(11):861-865. doi: 10.1080/09513590.2016.1193141

M. Kasum, K. Kurdija, S. Orešković, E. Čehić, D. Pavičić Baldani and L. Škrgatić, "Combined ovulation triggering with GnRH agonist and hCG in IVF patients", Gynecological Endocrinology, vol. 32, no. 11, pp. 861-865, November 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:785251. [Accessed: 06 May 2024]

Metadata
Title (english)Combined ovulation triggering with GnRH agonist and hCG in IVF patients
AuthorMiro Kasum
AuthorKristijan Kurdija
AuthorSlavko Orešković
AuthorErmin Čehić
AuthorDinka Pavičić-Baldani
AuthorLana Škrgatić
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The aim of the review is to analyse the combination of a gonadotrophin releasing hormone (GnRH) agonist with a human chorionic gonadotrophin (hCG) trigger, for final oocyte maturation in in vitro fertilisation (IVF) cycles. The concept being a ''dual trigger'' combines a single dose of the GnRH agonist with a reduced or standard dosage of hCG at the time of triggering. The use of a GnRH agonist with a reduced dose of hCG in high responders demonstrated luteal phase support with improved pregnancy rates, similar to those after conventional hCG and a low risk of ovarian hyperstimulation syndrome (OHSS). The administration of a GnRH agonist and a standard hCG in normal responders, demonstrated significantly improved live-birth rates and a higher number of embryos of excellent quality, or cryopreserved embryos. The concept of the ''double trigger" represents a combination of a GnRH agonist and a standard hCG, when used 40 and 34 h prior to ovum pick-up, respectively. The use of the ''double trigger" has been successfully offered in the treatment of empty follicle syndrome and in patients with a history of immature oocytes retrieved or with low/poor oocytes yield. Further prospective studies are required to confirm the aforementioned observations prior to clinical implementation.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleGynecological Endocrinology
Numberingvol. 32, no. 11, pp. 861-865
p-ISSN0951-3590
DOIhttps://doi.org/10.1080/09513590.2016.1193141
URN:NBNurn:nbn:hr:105:785251
Publication2016-11
Document URLhttp://doi.org/10.1080/09513590.2016.1193141
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 08:58:14