prikaz prve stranice dokumenta Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients
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Scientific paper - Original scientific paper
Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients
Scientific Reports, 7 (2017), 1; 1165. https://doi.org/10.1038/s41598-017-01367-2
Potočnjak, Ines; Trbušić, Matias; Dokoza Terešak, Sanda; Radulović, Bojana; Pregartner, Gudrun; Berghold, Andrea; Tiran, Beate; Marsche, Gunther; Degoricija, Vesna; Frank, Saša

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Potočnjak, I., Trbušić, M., Dokoza Terešak, S., Radulović, B., Pregartner, G., Berghold, A. ... Frank, S. (2017). Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients. Scientific Reports, 7. (1), 1165. doi: 10.1038/s41598-017-01367-2

Potočnjak, Ines, et al. "Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients." Scientific Reports, vol. 7, no. 1, 2017, p. 1165. https://doi.org/10.1038/s41598-017-01367-2

Potočnjak, Ines, Matias Trbušić, Sanda Dokoza Terešak, Bojana Radulović, Gudrun Pregartner, Andrea Berghold, Beate Tiran, Gunther Marsche, Vesna Degoricija and Saša Frank. "Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients." Scientific Reports 7, no. 1 (2017): 1165. https://doi.org/10.1038/s41598-017-01367-2

Potočnjak, I., et al. (2017) 'Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients', Scientific Reports, 7(1), p. 1165. doi: 10.1038/s41598-017-01367-2

Potočnjak I, Trbušić M, Dokoza Terešak S, Radulović B, Pregartner G, Berghold A, and sur.. Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients. Scientific Reports [Internet]. 2017 April 26 [cited 2024 November 26];7(1):1165. doi: 10.1038/s41598-017-01367-2

I. Potočnjak, et al., "Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients", Scientific Reports, vol. 7, no. 1, p. 1165, April 2017. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:690776. [Accessed: 26 November 2024]

Metadata
Title (english)Metabolic syndrome modulates association between endothelial lipase and lipid/lipoprotein plasma levels in acute heart failure patients
AuthorInes Potočnjak
AuthorMatias Trbušić
AuthorSanda Dokoza Terešak
AuthorBojana Radulović
AuthorGudrun Pregartner
AuthorAndrea Berghold
AuthorBeate Tiran
AuthorGunther Marsche
AuthorVesna Degoricija
AuthorSaša Frank
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
We hypothesised that the established association of endothelial lipase (EL) plasma levels with atherogenic lipid profile is altered in acute heart failure (AHF) and additionally affected by overlapping metabolic syndrome (MetS). We examined the association of EL plasma levels and lipid/lipoprotein plasma levels in AHF patients without and with overlapping MetS. The study was performed as a single-centre, observational study on 152 AHF patients, out of which 85 had overlapping MetS. In the no-MetS group, EL plasma levels were significantly positively correlated with plasma levels of atherogenic lipids/lipoproteins, including total cholesterol, low-density lipoprotein (LDL)-cholesterol, total LDL particles and triglycerides, but also with plasma levels of antiatherogenic high-density lipoprotein (HDL)-cholesterol, total HDL particles and small HDL particles. In the MetS group, EL plasma levels were positively correlated with triglyceride and small LDL-particle levels, and significantly negatively correlated with plasma levels of large HDL particles as well as with LDL- and HDL-particle size, respectively. EL- and lipid/lipoprotein- plasma levels were different in the no-MetS patients, compared to MetS patients. The association of EL with atherogenic lipid profile is altered in AHF and additionally modified by MetS, which strongly modulates EL- and lipid/lipoprotein-plasma levels in AHF.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleScientific Reports
Numberingvol. 7, no. 1, p. 1165
p-ISSN2045-2322
DOIhttps://doi.org/10.1038/s41598-017-01367-2
URN:NBNurn:nbn:hr:105:690776
Publication2017-04-26
Document URLhttps://doi.org/10.1038/s41598-017-01367-2
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 09:10:36