prikaz prve stranice dokumenta Successful treatment of disseminated Bacillus Calmette-Guérin disease in an HIV-infected child with a linezolid-containing regimen
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Scientific paper - Original scientific paper
Successful treatment of disseminated Bacillus Calmette-Guérin disease in an HIV-infected child with a linezolid-containing regimen
Case Reports in Infectious Diseases, 2016 (2016); 1528981. https://doi.org/10.1155/2016/1528981
Roglić, Srđan; Dickson, Drusia; Miše, Branko; Višković, Klaudija; Katalinić-Janković, Vera; Rutherford, George; Begovac, Josip

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Roglić, S., Dickson, D., Miše, B., Višković, K., Katalinić Janković, V., Rutherford, G. & Begovac, J. (2016). Successful treatment of disseminated Bacillus Calmette-Guérin disease in an HIV-infected child with a linezolid-containing regimen. Case Reports in Infectious Diseases, 2016., 1528981. doi: 10.1155/2016/1528981

Roglić, Srđan, et al. "Successful treatment of disseminated Bacillus Calmette-Guérin disease in an HIV-infected child with a linezolid-containing regimen." Case Reports in Infectious Diseases, vol. 2016, 2016, p. 1528981. https://doi.org/10.1155/2016/1528981

Roglić, Srđan, Drusia Dickson, Branko Miše, Klaudija Višković, Vera Katalinić Janković, George Rutherford and Josip Begovac. "Successful treatment of disseminated Bacillus Calmette-Guérin disease in an HIV-infected child with a linezolid-containing regimen." Case Reports in Infectious Diseases 2016 (2016): 1528981. https://doi.org/10.1155/2016/1528981

Roglić, S., et al. (2016) 'Successful treatment of disseminated Bacillus Calmette-Guérin disease in an HIV-infected child with a linezolid-containing regimen', Case Reports in Infectious Diseases, 2016, p. 1528981. doi: 10.1155/2016/1528981

Roglić S, Dickson D, Miše B, Višković K, Katalinić Janković V, Rutherford G, and sur.. Successful treatment of disseminated Bacillus Calmette-Guérin disease in an HIV-infected child with a linezolid-containing regimen. Case Reports in Infectious Diseases [Internet]. 2016 [cited 2024 November 29];2016:1528981. doi: 10.1155/2016/1528981

S. Roglić, et al., "Successful treatment of disseminated Bacillus Calmette-Guérin disease in an HIV-infected child with a linezolid-containing regimen", Case Reports in Infectious Diseases, vol. 2016, p. 1528981, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:543136. [Accessed: 29 November 2024]

Metadata
Title (english)Successful treatment of disseminated Bacillus Calmette-Guérin disease in an HIV-infected child with a linezolid-containing regimen
AuthorSrđan Roglić
AuthorDrusia Dickson
AuthorBranko Miše
AuthorKlaudija Višković
AuthorVera Katalinić-Janković
AuthorGeorge Rutherford
AuthorJosip Begovac
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Upon HIV infection diagnosis, an 8-month-old boy was transferred for evaluation of worsening respiratory distress requiring mechanical ventilation. Pneumocystis jirovecii pneumonia (PCP) was diagnosed; the boy also had a nonhealing ulcer at the site of vaccination with Statens Serum Institut (Danish strain) Bacillus Calmette-Guérin (BCG) vaccine and associated axillary lymphadenopathy. PCP treatment resulted in weaning from mechanical ventilation. Antimycobacterial treatment was immediately attempted but was discontinued because of hepatotoxicity. Over several months, he developed splenic lesions and then disseminated skin and cystic bone lesions. M. bovis was repeatedly cultured from both skin and bone lesions despite various multidrug antimycobacterial regimens which included linezolid. Eventually, treatment with a regimen of rifabutin, isoniazid, ethambutol, and linezolid led to definitive cure. Clinicians should consider a linezolid-containing regimen for treatment of severe disseminated BCG infection, especially if other drug regimens have failed. Although drug toxicity is a particular concern for young children, this patient received linezolid for 13 months without serious toxicity. This case also highlights the need for universal screening among pregnant women to prevent vertical transmission of HIV. Finally, routine immunization with BCG vaccine at birth should be questioned in countries with low and declining burden of tuberculosis.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCase Reports in Infectious Diseases
Numberingvol. 2016, p. 1528981
p-ISSN2090-6625
DOIhttps://doi.org/10.1155/2016/1528981
URN:NBNurn:nbn:hr:105:543136
Publication2016
Document URLhttps://doi.org/10.1155/2016/1528981
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 09:11:26