prikaz prve stranice dokumenta Kisspeptin as a promising oocyte maturation trigger for in vitro fertilisation in humans
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Scientific paper - Original scientific paper
Kisspeptin as a promising oocyte maturation trigger for in vitro fertilisation in humans
Gynecological Endocrinology, 33 (2017), 8; 583-587. https://doi.org/10.1080/09513590.2017.1309019
Kasum, Miro; Franulić, Daniela; Čehić, Ermin; Orešković, Slavko; Lila, Albert; Ejubović, Emina

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Kasum, M., Franulić, D., Čehić, E., Orešković, S., Lila, A. & Ejubović, E. (2017). Kisspeptin as a promising oocyte maturation trigger for in vitro fertilisation in humans. Gynecological Endocrinology, 33. (8), 583-587. doi: 10.1080/09513590.2017.1309019

Kasum, Miro, et al. "Kisspeptin as a promising oocyte maturation trigger for in vitro fertilisation in humans." Gynecological Endocrinology, vol. 33, no. 8, 2017, pp. 583-587. https://doi.org/10.1080/09513590.2017.1309019

Kasum, Miro, Daniela Franulić, Ermin Čehić, Slavko Orešković, Albert Lila and Emina Ejubović. "Kisspeptin as a promising oocyte maturation trigger for in vitro fertilisation in humans." Gynecological Endocrinology 33, no. 8 (2017): 583-587. https://doi.org/10.1080/09513590.2017.1309019

Kasum, M., et al. (2017) 'Kisspeptin as a promising oocyte maturation trigger for in vitro fertilisation in humans', Gynecological Endocrinology, 33(8), pp. 583-587. doi: 10.1080/09513590.2017.1309019

Kasum M, Franulić D, Čehić E, Orešković S, Lila A, Ejubović E. Kisspeptin as a promising oocyte maturation trigger for in vitro fertilisation in humans. Gynecological Endocrinology [Internet]. 2017 August [cited 2024 November 30];33(8):583-587. doi: 10.1080/09513590.2017.1309019

M. Kasum, D. Franulić, E. Čehić, S. Orešković, A. Lila and E. Ejubović, "Kisspeptin as a promising oocyte maturation trigger for in vitro fertilisation in humans", Gynecological Endocrinology, vol. 33, no. 8, pp. 583-587, August 2017. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:165983. [Accessed: 30 November 2024]

Metadata
Title (english)Kisspeptin as a promising oocyte maturation trigger for in vitro fertilisation in humans
AuthorMiro Kasum
AuthorDaniela Franulić
AuthorErmin Čehić
AuthorSlavko Orešković
AuthorAlbert Lila
AuthorEmina Ejubović
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The aim of this review is to analyse the effectiveness of exogenous kisspeptin administration as a novel alternative of triggering oocyte maturation, instead of currently used triggers such as human chorionic gonadotropin (hCG) or gonadotropin releasing hormone (GnRH) agonist, in women undergoing in vitro fertilisation (IVF) treatment. Kisspeptin has been considered a master regulator of two modes of GnRH and hence gonadotropin secretion, pulses and surges. Administration of kisspeptin-10 and kisspeptin-54 induces the luteinising hormone (LH) surge required for egg maturation and ovulation in animal investigations and LH release during the preovulatory phase of the menstrual cycle and hypothalamic amenorrhoea in humans. Exogenous kisspeptin-54 has been successfully administered as a promising method of triggering oocyte maturation, following ovarian stimulation with gonadotropins and GnRH antagonists in women undergoing IVF, due to its efficacy considering achieved pregnancy rates compared to hCG and GnRH agonists. Also, its safety in patients at high risk of developing ovarian hyperstimulation syndrome is noteworthy. Nevertheless, further studies would be desirable to establish the optimal trigger of egg maturation and to improve the reproductive outcome for women undergoing IVF treatment.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleGynecological Endocrinology
Numberingvol. 33, no. 8, pp. 583-587
p-ISSN0951-3590
DOIhttps://doi.org/10.1080/09513590.2017.1309019
URN:NBNurn:nbn:hr:105:165983
Publication2017-08
Document URLhttps://doi.org/10.1080/09513590.2017.1309019
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 09:18:01