prikaz prve stranice dokumenta Atrial fibrillation and risk of cardiovascular events and mortality in patients with symptomatic peripheral artery disease: A meta-analysis of prospective studies
  Download
PDF 392.87 KB
Scientific paper - Original scientific paper
Atrial fibrillation and risk of cardiovascular events and mortality in patients with symptomatic peripheral artery disease: A meta-analysis of prospective studies
Clinical Cardiology, 40 (2017), 12; 1231-1235. https://doi.org/10.1002/clc.22813
Vrsalović, Mislav; Presečki, Ana Vrsalović

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Vrsalović, M. & Presečki, A. V. (2017). Atrial fibrillation and risk of cardiovascular events and mortality in patients with symptomatic peripheral artery disease: A meta-analysis of prospective studies. Clinical Cardiology, 40. (12), 1231-1235. doi: 10.1002/clc.22813

Vrsalović, Mislav and Ana Vrsalović Presečki. "Atrial fibrillation and risk of cardiovascular events and mortality in patients with symptomatic peripheral artery disease: A meta-analysis of prospective studies." Clinical Cardiology, vol. 40, no. 12, 2017, pp. 1231-1235. https://doi.org/10.1002/clc.22813

Vrsalović, Mislav and Ana Vrsalović Presečki. "Atrial fibrillation and risk of cardiovascular events and mortality in patients with symptomatic peripheral artery disease: A meta-analysis of prospective studies." Clinical Cardiology 40, no. 12 (2017): 1231-1235. https://doi.org/10.1002/clc.22813

Vrsalović, M. and Presečki, A. V. (2017) 'Atrial fibrillation and risk of cardiovascular events and mortality in patients with symptomatic peripheral artery disease: A meta-analysis of prospective studies', Clinical Cardiology, 40(12), pp. 1231-1235. doi: 10.1002/clc.22813

Vrsalović M, Presečki AV. Atrial fibrillation and risk of cardiovascular events and mortality in patients with symptomatic peripheral artery disease: A meta-analysis of prospective studies. Clinical Cardiology [Internet]. 2017 December [cited 2024 November 26];40(12):1231-1235. doi: 10.1002/clc.22813

M. Vrsalović and A. V. Presečki, "Atrial fibrillation and risk of cardiovascular events and mortality in patients with symptomatic peripheral artery disease: A meta-analysis of prospective studies", Clinical Cardiology, vol. 40, no. 12, pp. 1231-1235, December 2017. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:985380. [Accessed: 26 November 2024]

Metadata
Title (english)Atrial fibrillation and risk of cardiovascular events and mortality in patients with symptomatic peripheral artery disease: A meta-analysis of prospective studies
AuthorMislav Vrsalović
AuthorAna Vrsalović Presečki
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
BACKGROUND: Atrial fibrillation (AF) is associated with adverse outcomes in terms of survival and morbidity. Peripheral artery disease (PAD) and AF share several common risk factors and often coexist. Whether AF has a prognostic role in patients with PAD has not been extensively studied. ----- HYPOTHESIS: AF is associated with major adverse cardiac events (MACE) and mortality in symptomatic PAD patients. ----- METHODS: Using MEDLINE and Scopus, we searched for studies published before December 2016 that evaluated cardiovascular outcomes based on the presence/absence of AF in a prospective manner with a follow-up period of ≥12 months. The outcomes were reported using a random-effects model, and heterogeneity was assessed using the I2 statistic. Sensitivity analyses were performed to test the contribution of each study to the overall results. ----- RESULTS: Six prospective studies (Newcastle-Ottawa score range, 7-9) with 14 656 patients were included in the final analysis (age range, 66-70 years; median follow-up, 1.4 years). Our pooled analysis found a significant association between AF and mortality (odds ratio: 2.52, 95% confidence interval: 1.91-3.34, I2 = 32.6%), without evidence of publication bias (P = 0.63). Meta-analysis showed a significant impact of AF on MACE (odds ratio: 2.54, 95% confidence interval: 1.78-3.63, I2 = 74.3%), without detected publication bias (P = 0.08). ----- CONCLUSIONS: AF is associated with increased risk of mortality and MACE in symptomatic PAD.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleClinical Cardiology
Numberingvol. 40, no. 12, pp. 1231-1235
p-ISSN0160-9289
DOIhttps://doi.org/10.1002/clc.22813
URN:NBNurn:nbn:hr:105:985380
Publication2017-12
Document URLhttp://doi.org/10.1002/clc.22813
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 09:54:22