prikaz prve stranice dokumenta Terminal ileum resection as a trigger for strongyloides stercoralis hyperinfection and ensuing serial sepsis in a 37-year-old patient with complicated Crohnʼs disease: a case report
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Scientific paper - Case study
Terminal ileum resection as a trigger for strongyloides stercoralis hyperinfection and ensuing serial sepsis in a 37-year-old patient with complicated Crohnʼs disease: a case report
Zeitschrift für Gastroenterologie, 56 (2018), 4; 380-383. https://doi.org/doi:10.1055/a-0578-9799
Topić, Mirjana; Čuković-Čavka, Silvija; Brinar, Marko; Kalauz, Mirjana; Škrlec, Ivica; Majerović, Matea

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Topić, M., Čuković Čavka, S., Brinar, M., Kalauz, M., Škrlec, I. & Majerović, M. (2018). Terminal ileum resection as a trigger for strongyloides stercoralis hyperinfection and ensuing serial sepsis in a 37-year-old patient with complicated Crohnʼs disease: a case report. Zeitschrift für Gastroenterologie, 56. (4), 380-383. doi: doi:10.1055/a-0578-9799

Topić, Mirjana, et al. "Terminal ileum resection as a trigger for strongyloides stercoralis hyperinfection and ensuing serial sepsis in a 37-year-old patient with complicated Crohnʼs disease: a case report." Zeitschrift für Gastroenterologie, vol. 56, no. 4, 2018, pp. 380-383. https://doi.org/doi:10.1055/a-0578-9799

Topić, Mirjana, Silvija Čuković Čavka, Marko Brinar, Mirjana Kalauz, Ivica Škrlec and Matea Majerović. "Terminal ileum resection as a trigger for strongyloides stercoralis hyperinfection and ensuing serial sepsis in a 37-year-old patient with complicated Crohnʼs disease: a case report." Zeitschrift für Gastroenterologie 56, no. 4 (2018): 380-383. https://doi.org/doi:10.1055/a-0578-9799

Topić, M., et al. (2018) 'Terminal ileum resection as a trigger for strongyloides stercoralis hyperinfection and ensuing serial sepsis in a 37-year-old patient with complicated Crohnʼs disease: a case report', Zeitschrift für Gastroenterologie, 56(4), pp. 380-383. doi: doi:10.1055/a-0578-9799

Topić M, Čuković Čavka S, Brinar M, Kalauz M, Škrlec I, Majerović M. Terminal ileum resection as a trigger for strongyloides stercoralis hyperinfection and ensuing serial sepsis in a 37-year-old patient with complicated Crohnʼs disease: a case report. Zeitschrift für Gastroenterologie [Internet]. 2018 April [cited 2024 April 30];56(4):380-383. doi: doi:10.1055/a-0578-9799

M. Topić, S. Čuković Čavka, M. Brinar, M. Kalauz, I. Škrlec and M. Majerović, "Terminal ileum resection as a trigger for strongyloides stercoralis hyperinfection and ensuing serial sepsis in a 37-year-old patient with complicated Crohnʼs disease: a case report", Zeitschrift für Gastroenterologie, vol. 56, no. 4, pp. 380-383, April 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:024217. [Accessed: 30 April 2024]

Metadata
Title (english)Terminal ileum resection as a trigger for strongyloides stercoralis hyperinfection and ensuing serial sepsis in a 37-year-old patient with complicated Crohnʼs disease: a case report
AuthorMirjana Topić
AuthorSilvija Čuković-Čavka
AuthorMarko Brinar
AuthorMirjana Kalauz
AuthorIvica Škrlec
AuthorMatea Majerović
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The nematode Strongyloides stercoralis, outside the tropics and subtropics present in small endemic foci, can cause an infection after direct skin contact with contaminated soil containing infective filariform larvae and, rarely, after intimate interhuman contact or after transplantation of an infected solid organ. Following skin penetration, migration, and maturation through several stages, a small number of invasive filariform larvae can develop anew in the gut lumen, perpetuating new cycles of penetration, tissue migration, and reproduction, without leaving the host. In a state of immunosuppression, autoinfection can progress to life-threatening hyperinfection and/or infection disseminated through virtually any organ. In developed countries, the most frequently recognized risk for severe hyperinfection is corticosteroid therapy, but this has been also described in malnourished, alcoholic, cancer, and transplant patients. Due to the frequent need for immunosuppressive therapy, patients suffering from inflammatory bowel disease (IBD) are susceptible to develop overwhelming strongyloidiasis. Strongyloidiasis can be easily overlooked in clinical settings, and in many European regions there is poor insight into the epidemiological burden of this disease. We present a case of S. stercoralis hyperinfection that triggered 3 successive episodes of sepsis caused by pathogens of the gut flora in a young patient suffering from stenotic form of Crohn's disease. S. stercoralis hyperinfection occurred in the corticosteroid-free period, shortly after resection of the terminal ileum, which was probably the trigger for the overwhelming course. The patient was successfully treated with 10-day albendazole therapy.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleZeitschrift für Gastroenterologie
Numberingvol. 56, no. 4, pp. 380-383
p-ISSN0044-2771
DOIhttps://doi.org/doi:10.1055/a-0578-9799
URN:NBNurn:nbn:hr:105:024217
Publication2018-04
Document URLhttp://doi.org/10.1055/a-0578-9799
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 10:16:48