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Scientific paper - Review paper
Cefpodoxime proxetil as a therapeutic option in switching therapy for infective endocarditis in children: case reports and literature review
Journal of Chemotherapy, 31 (2019), 6; 354-358. https://doi.org/10.1080/1120009X.2019.1603797
Krajcar, Nina; Marić, Lorna Stemberger; Šarić, Dalibor; Milić, Neven; Tešović, Goran

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Krajcar, N., Marić, L. S., Šarić, D., Milić, N. & Tešović, G. (2019). Cefpodoxime proxetil as a therapeutic option in switching therapy for infective endocarditis in children: case reports and literature review. Journal of Chemotherapy, 31. (6), 354-358. doi: 10.1080/1120009X.2019.1603797

Krajcar, Nina, et al. "Cefpodoxime proxetil as a therapeutic option in switching therapy for infective endocarditis in children: case reports and literature review." Journal of Chemotherapy, vol. 31, no. 6, 2019, pp. 354-358. https://doi.org/10.1080/1120009X.2019.1603797

Krajcar, Nina, Lorna Stemberger Marić, Dalibor Šarić, Neven Milić and Goran Tešović. "Cefpodoxime proxetil as a therapeutic option in switching therapy for infective endocarditis in children: case reports and literature review." Journal of Chemotherapy 31, no. 6 (2019): 354-358. https://doi.org/10.1080/1120009X.2019.1603797

Krajcar, N., et al. (2019) 'Cefpodoxime proxetil as a therapeutic option in switching therapy for infective endocarditis in children: case reports and literature review', Journal of Chemotherapy, 31(6), pp. 354-358. doi: 10.1080/1120009X.2019.1603797

Krajcar N, Marić LS, Šarić D, Milić N, Tešović G. Cefpodoxime proxetil as a therapeutic option in switching therapy for infective endocarditis in children: case reports and literature review. Journal of Chemotherapy [Internet]. 2019 October 31 [cited 2024 May 04];31(6):354-358. doi: 10.1080/1120009X.2019.1603797

N. Krajcar, L. S. Marić, D. Šarić, N. Milić and G. Tešović, "Cefpodoxime proxetil as a therapeutic option in switching therapy for infective endocarditis in children: case reports and literature review", Journal of Chemotherapy, vol. 31, no. 6, pp. 354-358, October 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:117427. [Accessed: 04 May 2024]

Metadata
Title (english)Cefpodoxime proxetil as a therapeutic option in switching therapy for infective endocarditis in children: case reports and literature review
AuthorNina Krajcar
AuthorLorna Stemberger Marić
AuthorDalibor Šarić
AuthorNeven Milić
AuthorGoran Tešović
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Infective endocarditis (IE) is uncommon in children, affecting predominantly subjects with congenital heart disease (CHD) and patients with indwelling central lines. The principles of antibiotic treatment in paediatric population are similar to those in adults. Prolonged intravenous administration of bactericidal rather than bacteriostatic agents is preferred. Outpatient intravenous therapy after initial treatment in the hospital may be considered only in selected patients. Partial oral treatment has been described in cases of left-sided, uncomplicated IE caused by common pathogens in adult patients. There are no guidelines or trials in paediatric population regarding switching therapy from intravenous to oral route. We present two cases of IE in children caused by uncommon pathogenic bacteria (Abiotrophia defectiva and Haemophilus parainfluenzae) successfully treated with oral third-generation cephalosporin - cefpodoxime proxetil after initial intravenous therapy. This paper provides observations on different therapeutic approach for IE in children as well as another potential use of cefpodoxime proxetil.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleJournal of Chemotherapy
Numberingvol. 31, no. 6, pp. 354-358
p-ISSN1120-009X
DOIhttps://doi.org/10.1080/1120009X.2019.1603797
URN:NBNurn:nbn:hr:105:117427
Publication2019-10-31
Document URLhttps://doi.org/10.1080/1120009X.2019.1603797
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 10:41:39