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Scientific paper - Original scientific paper
Nucleolar protein 1 (Nol1) expression in the mouse brain
Collegium Antropologicum, 32 (2008), S. 1; 123-126. urn:nbn:hr:105:009086
Mitrečić, Dinko; Malnar, Tajana; Gajović, Srećko

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Mitrečić, D., Malnar, T. & Gajović, S. (2008). Nucleolar protein 1 (Nol1) expression in the mouse brain. Collegium Antropologicum, 32. (S. 1), 123-126. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:009086

Mitrečić, Dinko, et al. "Nucleolar protein 1 (Nol1) expression in the mouse brain." Collegium Antropologicum, vol. 32, no. S. 1, 2008, pp. 123-126. https://urn.nsk.hr/urn:nbn:hr:105:009086

Mitrečić, Dinko, Tajana Malnar and Srećko Gajović. "Nucleolar protein 1 (Nol1) expression in the mouse brain." Collegium Antropologicum 32, no. S. 1 (2008): 123-126. https://urn.nsk.hr/urn:nbn:hr:105:009086

Mitrečić, D., Malnar, T. and Gajović, S. (2008) 'Nucleolar protein 1 (Nol1) expression in the mouse brain', Collegium Antropologicum, 32(S. 1), pp. 123-126. Available at: https://urn.nsk.hr/urn:nbn:hr:105:009086 (Accessed 14 May 2024)

Mitrečić D, Malnar T, Gajović S. Nucleolar protein 1 (Nol1) expression in the mouse brain. Collegium Antropologicum [Internet]. 2008 January [cited 2024 May 14];32(S. 1):123-126. Available at: https://urn.nsk.hr/urn:nbn:hr:105:009086

D. Mitrečić, T. Malnar and S. Gajović, "Nucleolar protein 1 (Nol1) expression in the mouse brain", Collegium Antropologicum, vol. 32, no. S. 1, pp. 123-126, January 2008. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:009086. [Accessed: 14 May 2024]

Metadata
Title (english)Nucleolar protein 1 (Nol1) expression in the mouse brain
AuthorDinko Mitrečić
AuthorTajana Malnar
AuthorSrećko Gajović
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Nucleolar protein 1 (Nol1) is a cell cycle dependent gene highly expressed in proliferating tissues. In order to test whether Nol1 could be used as a marker of dividing neural stem cells within mouse brain, Nol1 expression was analyzed using mouse carrying a gene trap modification of Nol1 gene. High Nol1 expression was found within the hippocampus, olfactory bulb, cerebral and cerebellar cortex. Nol1 was expressed not only in the dividing cells within the brain, but as well in the postmitotic neurons. This suggested a general role of Nol1 in assembling of ribosomes in cells with high protein production.
Abstract (croatian)
Bjelančevina jezgrice 1 (Nucleolar protein 1, Nol1) je gen izražen u stanicama koje se umnažaju, te mu izražaj ovisi o fazi staničnog ciklusa. Kako bismo testirali hipotezu da je Nol1 potencijalni biljeg stanica u diobi u mozgu miša (živčane matične stanice), analizirali smo izražaj Nol1 u mozgu miša kojem je Nol1 preinačen postupkom genske zamke. Ekspresija Nol1 je nađena u hipokampusu, njušnom bulbusu, te u kori velikog i malog mozga. Ovaj nalaz je ukazao da Nol1 nije izražen samo u stanicama koje se dijele, već i u diferenciranim živčanim stanicama. Pretpostavljeno je kako Nol1 ima ulogu u sintezi ribosoma i bjelančevina u stanicama živčanog sustava.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleCollegium Antropologicum
Numberingvol. 32, no. S. 1, pp. 123-126
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:009086
Publication2008-01
Document URLhttps://hrcak.srce.hr/24565
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 10:48:26