A hand is the most perfect part of the human body movement system. The complex anatomy of the hand combined with its daily loads, often overloads can result in a variety of injuries and diseases that can lead to its malfunction or dysfunction. With the loss of hand function, quality of people's everyday practical, emotional and social skills is extremely reduced, and a proper treatment of such injuries and diseases as soon as possible is crucial. Since injuries of hand often affect several tissues (skin, tendons, blood vessels, nerves, bones), such injuries are called complex hand injuries, and each hand structure is necessary to be reconstructed as best as possible to be functional as it was before. It is possible to take care and handle such complex injuries only in specialized well-equipped medical centers with well educated staff. Hand surgery often requires the use of microsurgical techniques using a magnifying glasses or operating microscope, special surgical instruments and skills that surgeon must have. After radical debridement, which is a prerequisite for a successful reconstruction, surgeons select the optimal type of reconstruction. In process of selecting the reconstructive procedure several critical factors should be taken into account including: the size of the defect, the type of the missing tissue, state of the wound (possible exulceration, colonization or infection), localization of the defect and length of pedicle needed to reach adequate blood vessels. Based on these facts, surgeon selects one of possible types of reconstruction of complex injuries: replantation, revascularization, connection of slashed structures, and reconstruction of structures that are irreversibly damaged or missing using flaps and grafts, or a combination of these procedures.