prikaz prve stranice dokumenta Tuberculosis in HIV-infected patients in Croatia between 1986 and 2005
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Scientific paper - Original scientific paper
Tuberculosis in HIV-infected patients in Croatia between 1986 and 2005
Collegium Antropologicum, 30 (2006), Suppl.; 53-58. urn:nbn:hr:105:244703
Puljiz, Ivan; Begovac, Josip

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Puljiz, I. & Begovac, J. (2006). Tuberculosis in HIV-infected patients in Croatia between 1986 and 2005. Collegium Antropologicum, 30. (Suppl.), 53-58. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:244703

Puljiz, Ivan and Josip Begovac. "Tuberculosis in HIV-infected patients in Croatia between 1986 and 2005." Collegium Antropologicum, vol. 30, no. Suppl., 2006, pp. 53-58. https://urn.nsk.hr/urn:nbn:hr:105:244703

Puljiz, Ivan and Josip Begovac. "Tuberculosis in HIV-infected patients in Croatia between 1986 and 2005." Collegium Antropologicum 30, no. Suppl. (2006): 53-58. https://urn.nsk.hr/urn:nbn:hr:105:244703

Puljiz, I. and Begovac, J. (2006) 'Tuberculosis in HIV-infected patients in Croatia between 1986 and 2005', Collegium Antropologicum, 30(Suppl.), pp. 53-58. Available at: https://urn.nsk.hr/urn:nbn:hr:105:244703 (Accessed 22 November 2024)

Puljiz I, Begovac J. Tuberculosis in HIV-infected patients in Croatia between 1986 and 2005. Collegium Antropologicum [Internet]. 2006 December [cited 2024 November 22];30(Suppl.):53-58. Available at: https://urn.nsk.hr/urn:nbn:hr:105:244703

I. Puljiz and J. Begovac, "Tuberculosis in HIV-infected patients in Croatia between 1986 and 2005", Collegium Antropologicum, vol. 30, no. Suppl., pp. 53-58, December 2006. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:244703. [Accessed: 22 November 2024]

Metadata
Title (english)Tuberculosis in HIV-infected patients in Croatia between 1986 and 2005
AuthorIvan Puljiz
AuthorJosip Begovac
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
A retrospective medical chart review was performed on 65 HIV-infected patients with tuberculosis hospitalized between 1986 and 2006 at the University Hospital for Infectious Diseases "Dr. Fran Mihaljevic", Zagreb. Thirty two patients presented with pulmonary involvement, 13 with extrapulmonary, and 20 patients had disseminated tuberculosis. Forty five patients had an abnormal chest X-ray. Mycobacterium tuberculosis was identified in 35 (53.9%) patients. Ten (15.3%) of 65 patients had already been receiving antiviral therapy, while another 31 (47.7%) initiated antiviral therapy after antituberculosis therapy. Tuberculosis-associated immune reconstitution inflammatory syndrome was observed in 11/27 (40.7%) patients. Forty one patient received the standard six month course of antituberculous therapy, while in 12 patients the therapy was prolonged. Twenty one patient (32%) experienced an adverse event to antituberculosis drugs. Twelve patients died (18.5%). After the introduction of highly active antiviral therapy (HAART) the mortality decreased. The incidence of tuberculosis in HIV-infected patients in Croatia is increasing, and tuberculosis is still an important opportunistic infection in our HIV-infected patients.
Abstract (croatian)
Rad se temelji na retrospektivnoj analizi 65 HIV-pozitivnih bolesnika s tuberkulozom koji su bili hospitalizirani u Klinici za infektivne bolesti »Dr. Fran Mihaljević« u Zagrebu od 1986. do 2005. godine. Trideset i dva bolesnika su imala plućni oblik bolesti, 13 izvanplućni, a 20 je imalo diseminiranu tuberkulozu. Patološki nalaz na rendgenskoj slici pluća otkriven je u 45 bolesnika. Mycobaterium tuberculosis je dokazan u 53,9% bolesnika. Deset (15,3%) bolesnika je bilo na antivirusnoj terapiji prije dijagnosticiranja tuberkuloze dok je antivirusna terapija uvedena u 31 (47,7%) bolesnika nakon započinjanja liječenja tuberkulostaticima. Imunorekonstruktivni inflamatorni sindrom je zabilježen u 11/27 (40,7%) bolesnika. Standardno šesto mjesečno liječenje provedeno je u 41 bolesnika, a 12 bolesnika liječeno je dulje. Nuspojave su zabilježene u 21 bolesnika. Umrlo je 12 (18,5%) bolesnika. Nakon uvođenja visoko učinkovite antiretrovirusne terapije (HAART) smanjuje se smrtnost. Incidencija tuberkuloze u HIV-pozitivnih osoba u Hrvatskoj je u porastu, a tuberkuloza je važna oportunistička infekcija u naših HIV-pozitivnih bolesnika.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium Antropologicum
Numberingvol. 30, no. Suppl., pp. 53-58
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:244703
Publication2006-12
Document URLhttps://hrcak.srce.hr/27710
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 11:02:07