prikaz prve stranice dokumenta Initial patency of the infarct-related artery in patients with acute ST elevation myocardial infarction is related to platelet response to aspirin
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Scientific paper - Original scientific paper
Initial patency of the infarct-related artery in patients with acute ST elevation myocardial infarction is related to platelet response to aspirin
International Journal of Cardiology, 140 (2010), 3; 356-358. https://doi.org/10.1016/j.ijcard.2008.11.031
Skorić, Boško; Miličić, Davor; Lovrić, Daniel; Gornik, Ivan; Narančić Skorić, Kristina; Sertić, Jadranka

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Skorić, B., Miličić, D., Lovrić, D., Gornik, I., Narančić Skorić, K. & Sertić, J. (2010). Initial patency of the infarct-related artery in patients with acute ST elevation myocardial infarction is related to platelet response to aspirin. International Journal of Cardiology, 140. (3), 356-358. doi: 10.1016/j.ijcard.2008.11.031

Skorić, Boško, et al. "Initial patency of the infarct-related artery in patients with acute ST elevation myocardial infarction is related to platelet response to aspirin." International Journal of Cardiology, vol. 140, no. 3, 2010, pp. 356-358. https://doi.org/10.1016/j.ijcard.2008.11.031

Skorić, Boško, Davor Miličić, Daniel Lovrić, Ivan Gornik, Kristina Narančić Skorić and Jadranka Sertić. "Initial patency of the infarct-related artery in patients with acute ST elevation myocardial infarction is related to platelet response to aspirin." International Journal of Cardiology 140, no. 3 (2010): 356-358. https://doi.org/10.1016/j.ijcard.2008.11.031

Skorić, B., et al. (2010) 'Initial patency of the infarct-related artery in patients with acute ST elevation myocardial infarction is related to platelet response to aspirin', International Journal of Cardiology, 140(3), pp. 356-358. doi: 10.1016/j.ijcard.2008.11.031

Skorić B, Miličić D, Lovrić D, Gornik I, Narančić Skorić K, Sertić J. Initial patency of the infarct-related artery in patients with acute ST elevation myocardial infarction is related to platelet response to aspirin. International Journal of Cardiology [Internet]. 2010 April 30 [cited 2024 December 27];140(3):356-358. doi: 10.1016/j.ijcard.2008.11.031

B. Skorić, D. Miličić, D. Lovrić, I. Gornik, K. Narančić Skorić and J. Sertić, "Initial patency of the infarct-related artery in patients with acute ST elevation myocardial infarction is related to platelet response to aspirin", International Journal of Cardiology, vol. 140, no. 3, pp. 356-358, April 2010. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:022699. [Accessed: 27 December 2024]

Metadata
Title (english)Initial patency of the infarct-related artery in patients with acute ST elevation myocardial infarction is related to platelet response to aspirin
AuthorBoško Skorić
AuthorDavor Miličić
AuthorDaniel Lovrić
AuthorIvan Gornik
AuthorKristina Narančić Skorić
AuthorJadranka Sertić
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
INTRODUCTION: A proportion of patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary angiography (PCI) presents with patent infarct-related artery (IRA) on initial angiography. We tested the hypothesis that stronger platelet response to aspirin in these patients at admission might be associated with higher initial coronary flow in the IRA. ----- METHODS: Platelet response to aspirin was assessed with Multiplate((R)) ASPI-test before coronary angiography in 70 patients on previous aspirin treatment admitted for acute STEMI. Coronary flow on initial angiogram was evaluated quantitatively according to the Thrombolysis in Myocardial Infarction (TIMI) grading system. Depending on the degree of arachidonic acid (AA) induced platelet aggregation in ASPI-test, patients were stratified into four quartiles and compared according to initial TIMI flow. ----- RESULTS: When TIMI flow was compared according to quartiles of platelet aggregation in ASPI-test, we have found significantly higher frequency of TIMI-2 and TIMI-3 flow among patients with low values of ASPI-test, i.e. with stronger aspirin response (P=0.014). None of the patients in the highest quartile of ASPI-test had TIMI flow of 2 or 3. ----- CONCLUSIONS: Patients with stronger antiplatelet response to aspirin therapy in acute STEMI are more likely to present with spontaneous IRA recanalization.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleInternational Journal of Cardiology
Numberingvol. 140, no. 3, pp. 356-358
p-ISSN0167-5273
DOIhttps://doi.org/10.1016/j.ijcard.2008.11.031
URN:NBNurn:nbn:hr:105:022699
Publication2010-04-30
Document URLhttps://doi.org/10.1016/j.ijcard.2008.11.031
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 11:09:27