prikaz prve stranice dokumenta Neuroendocrine breast carcinoma metastatic to renal cell carcinoma and ipsilateral adrenal gland
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Scientific paper - Case study
Neuroendocrine breast carcinoma metastatic to renal cell carcinoma and ipsilateral adrenal gland
Pathology, Research and Practice, 204 (2008), 11; 851-855. https://doi.org/10.1016/j.prp.2008.04.006
Ulamec, Monika; Tomas, Davor; Perić-Balja, Melita; Spajić, Borislav; Hes, Ondrej; Krušlin, Božo

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Ulamec, M., Tomas, D., Perić Balja, M., Spajić, B., Hes, O. & Krušlin, B. (2008). Neuroendocrine breast carcinoma metastatic to renal cell carcinoma and ipsilateral adrenal gland. Pathology, Research and Practice, 204. (11), 851-855. doi: 10.1016/j.prp.2008.04.006

Ulamec, Monika, et al. "Neuroendocrine breast carcinoma metastatic to renal cell carcinoma and ipsilateral adrenal gland." Pathology, Research and Practice, vol. 204, no. 11, 2008, pp. 851-855. https://doi.org/10.1016/j.prp.2008.04.006

Ulamec, Monika, Davor Tomas, Melita Perić Balja, Borislav Spajić, Ondrej Hes and Božo Krušlin. "Neuroendocrine breast carcinoma metastatic to renal cell carcinoma and ipsilateral adrenal gland." Pathology, Research and Practice 204, no. 11 (2008): 851-855. https://doi.org/10.1016/j.prp.2008.04.006

Ulamec, M., et al. (2008) 'Neuroendocrine breast carcinoma metastatic to renal cell carcinoma and ipsilateral adrenal gland', Pathology, Research and Practice, 204(11), pp. 851-855. doi: 10.1016/j.prp.2008.04.006

Ulamec M, Tomas D, Perić Balja M, Spajić B, Hes O, Krušlin B. Neuroendocrine breast carcinoma metastatic to renal cell carcinoma and ipsilateral adrenal gland. Pathology, Research and Practice [Internet]. 2008 November [cited 2024 May 05];204(11):851-855. doi: 10.1016/j.prp.2008.04.006

M. Ulamec, D. Tomas, M. Perić Balja, B. Spajić, O. Hes and B. Krušlin, "Neuroendocrine breast carcinoma metastatic to renal cell carcinoma and ipsilateral adrenal gland", Pathology, Research and Practice, vol. 204, no. 11, pp. 851-855, November 2008. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:495661. [Accessed: 05 May 2024]

Metadata
Title (english)Neuroendocrine breast carcinoma metastatic to renal cell carcinoma and ipsilateral adrenal gland
AuthorMonika Ulamec
AuthorDavor Tomas
AuthorMelita Perić-Balja
AuthorBorislav Spajić
AuthorOndrej Hes
AuthorBožo Krušlin
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
We report on a 60-year-old woman with neuroendocrine carcinoma of the left breast metastasizing to renal cell carcinoma (RCC) of the left kidney and to adrenal gland. A yellow, well-circumscribed tumor, 11 cm in largest diameter and limited to the kidney, was found. Histopathology revealed RCC with foci of neuroendocrine differentiation. Solid sheets of hyperchromatic epithelioid cells with high mitotic activity were found between typical clear cells of RCC. These cells were CAM5,2 and E-cadherin focally positive, synaptophysin and NSE weakly positive, CK19 moderately positive, and AE1-AE3 and EMA strongly positive. Chromogranin A, CD10, CK 14, CK 20, HER2 (score 1+), vimentin, and HMB45 were negative. The left adrenal gland contained multiple, separate foci of a tumor composed of neuroendocrine components. Because of the biphasic tumor in the kidney, extensive clinical examination and further analyses were recommended. Tumor in the left breast was revealed. Two months later, the patient underwent mastectomy with axillary lymph node dissection. The tumor was histologically and immunohistochemically similar to the neuroendocrine component within RCC. All axillary nodes were positive. To our knowledge, this is the first case of neuroendocrine breast carcinoma with metastasis to renal cell carcinoma and ipsilateral adrenal gland.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titlePathology, Research and Practice
Numberingvol. 204, no. 11, pp. 851-855
p-ISSN0344-0338
DOIhttps://doi.org/10.1016/j.prp.2008.04.006
URN:NBNurn:nbn:hr:105:495661
Publication2008-11
Document URLhttps://doi.org/10.1016/j.prp.2008.04.006
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 11:11:01