prikaz prve stranice dokumenta Application of a novel bone osteotomy plate leads to reduction in heat-induced bone tissue necrosis in sheep
  Download
PDF 331.1 KB
Scientific paper - Original scientific paper
Application of a novel bone osteotomy plate leads to reduction in heat-induced bone tissue necrosis in sheep
Collegium Antropologicum, 32 (2008), 4; 1229-1237. urn:nbn:hr:105:537473
Bekić, Marijo; Davila, Slavko; Hrskanović, Mato; Bekić, Marijana; Seiwerth, Sven; Erdeljić, Viktorija; Capak, Darko; Butković, Vladimir

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Bekić, M., Davila, S., Hrskanović, M., Bekić, M., Seiwerth, S., Erdeljić, V. ... Butković, V. (2008). Application of a novel bone osteotomy plate leads to reduction in heat-induced bone tissue necrosis in sheep. Collegium Antropologicum, 32. (4), 1229-1237. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:537473

Bekić, Marijo, et al. "Application of a novel bone osteotomy plate leads to reduction in heat-induced bone tissue necrosis in sheep." Collegium Antropologicum, vol. 32, no. 4, 2008, pp. 1229-1237. https://urn.nsk.hr/urn:nbn:hr:105:537473

Bekić, Marijo, Slavko Davila, Mato Hrskanović, Marijana Bekić, Sven Seiwerth, Viktorija Erdeljić, Darko Capak and Vladimir Butković. "Application of a novel bone osteotomy plate leads to reduction in heat-induced bone tissue necrosis in sheep." Collegium Antropologicum 32, no. 4 (2008): 1229-1237. https://urn.nsk.hr/urn:nbn:hr:105:537473

Bekić, M., et al. (2008) 'Application of a novel bone osteotomy plate leads to reduction in heat-induced bone tissue necrosis in sheep', Collegium Antropologicum, 32(4), pp. 1229-1237. Available at: https://urn.nsk.hr/urn:nbn:hr:105:537473 (Accessed 03 May 2024)

Bekić M, Davila S, Hrskanović M, Bekić M, Seiwerth S, Erdeljić V, and sur.. Application of a novel bone osteotomy plate leads to reduction in heat-induced bone tissue necrosis in sheep. Collegium Antropologicum [Internet]. 2008 December [cited 2024 May 03];32(4):1229-1237. Available at: https://urn.nsk.hr/urn:nbn:hr:105:537473

M. Bekić, et al., "Application of a novel bone osteotomy plate leads to reduction in heat-induced bone tissue necrosis in sheep", Collegium Antropologicum, vol. 32, no. 4, pp. 1229-1237, December 2008. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:537473. [Accessed: 03 May 2024]

Metadata
Title (english)Application of a novel bone osteotomy plate leads to reduction in heat-induced bone tissue necrosis in sheep
AuthorMarijo Bekić
AuthorSlavko Davila
AuthorMato Hrskanović
AuthorMarijana Bekić
AuthorSven Seiwerth
AuthorViktorija Erdeljić
AuthorDarko Capak
AuthorVladimir Butković
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Previous studies have shown substantial effect thermal damage can have on new bone formation following osteotomy. In this study we evaluated the extent of thermal damage which occurs in four different methods of osteotomy and the effects it can have on bone healing. We further wanted to test whether a special osteotomy plate we constructed can lead to diminished heat generation during osteotomy and enhanced bone healing. The four methods evaluated included osteotomy performed by chisel, a newly constructed osteotomy plate, Gigly and oscillating saw. Twelve adult sheep underwent osteotomy performed on both tibiae. Bone fragments were stabilized using a fixation plate. Callus size was assessed using standard radiographs. Densitometry and histological evaluation were performed at 8 weeks following osteotomy. Temperature measurements were performed both in vivo during the operation, and ex vivo on explanted tibiae. The defects healed without complications and showed typical course of secondary fracture healing with callus ingrowth into the osteotomy gap. Radiographic examination of bone healing showed a tendency towards more callus formation in bones osteotomized using Gigly and oscillating saw, but this difference lacked significance. Use of Gigly and oscillating saw elicited much higher temperatures at the bone cortex surface, which subsequently lead to slightly impaired bone healing according to histological analysis. BMD was equal among all bones. In conclusion, the time required for complete healing of the defect differed depended greatly on the instruments used. The newly constructed osteotomy plate showed best results based on histological findings of capillary and osteoblast density.
Abstract (croatian)
Iz dostupne literature jasno je vidljiv negativan učinak topline na formiranje novog koštanog tkiva nakon osteotomije. Naše istraživanje je ispitivalo različiti stupanj toplinskog oštećenja kosti primjenom četiri različite tehnike osteotomije. Svrha nam je bila pokazati smanjuje li novokonstruirana pločica za osteotomiju toplinsko oštećenje, čime poboljšava cijeljenje kosti. Vrste instrumenata za osteotomiju koje smo istraživali su bili dlijeto, novokonstruirana pločica za osteotomiju, Giglijeva i oscilacijska pila. Kod dvanaest zrelih ovaca smo osteotomirali obje stražnje tibije. Primjenom pločice za osteosintezu smo fiksirali koštane ulomke. Stvaranje kalusa smo pratili na kontrolnim RTG slikama. Osam tjedana poslije osteotomije učinili smo denzitometrijsko i histološku obradu osteotomiranih kosti. Temperaturu koja se oslobađa pri osteotomiji smo mjerili in vivo za vrijeme zahvata te in vitro na izoliranim kostima. Koštani defekti su cijelili bez komplikacija uz karakterističnu sliku sekundarnog cijeljenja kosti uz urastanje kalusa u osteotomijsku pukotinu. Radiološko istraživanje koštanog cijeljenja je pokazalo pojačano stvaranje kalusa u kostima osteotomiranim Giglijevom i oscilacijskom pilom, ali ova različitost nije bila statistički značajna. Giglijeva i oscilacijska pila oslobađaju znatno veću količinu topline na površini kosti, što rezultira oslabljenim koštanim cijeljenjem što smo pokazali histološkim istraživanjem. Sve kosti su imale sličnu mineralnu gustoću. Zaključno, vrijeme potrebno za kompletno cijeljenje koštanog defekta u velikoj mjeri ovisi o instrumentu koji koristimo u svrhu osteotomije. Na temelju histološkog mjerenja gustoće osteoblasta i kapilara, novokonstruirana pločica je pokazala najuspješnije cijeljenje uz minimalno termičko i biomehaničko oštećenje kosti.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium Antropologicum
Numberingvol. 32, no. 4, pp. 1229-1237
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:537473
Publication2008-12
Document URLhttps://hrcak.srce.hr/34310
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 11:12:24