prikaz prve stranice dokumenta Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients
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Scientific paper - Original scientific paper
Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients
Croatian Medical Journal, 51 (2010), 1; 48-53. https://doi.org/10.3325/cmj.2010.51.48
Polašek, Ozren; Gunjača, Grgo; Kolčić, Ivana; Zgaga, Lina; Džijan, Snježana; Smolić, Robert; Smolić, Martina; Milas-Ahić, Jasminka; Šerić, Vatroslav; Galić, Josip; Tucak-Zorić, Sandra; Tucak, Antun; Rudan, Igor; Lauc, Gordan

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Polašek, O., Gunjača, G., Kolčić, I., Zgaga, L., Džijan, S., Smolić, R. ... Lauc, G. (2010). Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients. Croatian Medical Journal, 51. (1), 48-53. doi: 10.3325/cmj.2010.51.48

Polašek, Ozren, et al. "Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients." Croatian Medical Journal, vol. 51, no. 1, 2010, pp. 48-53. https://doi.org/10.3325/cmj.2010.51.48

Polašek, Ozren, Grgo Gunjača, Ivana Kolčić, Lina Zgaga, Snježana Džijan, Robert Smolić, Martina Smolić, et al. "Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients." Croatian Medical Journal 51, no. 1 (2010): 48-53. https://doi.org/10.3325/cmj.2010.51.48

Polašek, O., et al. (2010) 'Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients', Croatian Medical Journal, 51(1), pp. 48-53. doi: 10.3325/cmj.2010.51.48

Polašek O, Gunjača G, Kolčić I, Zgaga L, Džijan S, Smolić R, and sur.. Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients. Croatian Medical Journal [Internet]. 2010 February 15 [cited 2024 April 30];51(1):48-53. doi: 10.3325/cmj.2010.51.48

O. Polašek, et al., "Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients", Croatian Medical Journal, vol. 51, no. 1, pp. 48-53, February 2010. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:386603. [Accessed: 30 April 2024]

Metadata
Title (english)Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients
AuthorOzren Polašek
AuthorGrgo Gunjača
AuthorIvana Kolčić
AuthorLina Zgaga
AuthorSnježana Džijan
AuthorRobert Smolić
AuthorMartina Smolić
AuthorJasminka Milas-Ahić
AuthorVatroslav Šerić
AuthorJosip Galić
AuthorSandra Tucak-Zorić
AuthorAntun Tucak
AuthorIgor Rudan
AuthorGordan Lauc
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Aim. To investigate the association of nephrolithiasis and solute carrier family 2, facilitated glucose transporter, member 9 (SLC2A9), also known as glucose transporter type 9, Glut9. ----- Methods. A total of 145 participants were recruited in the period April-October 2008 from the Department of Mineral Research of the Medical School Osijek, Osijek, Croatia; 58 (40%) had confirmed nephrolithiasis and 87 (60%) were asymptomatic. Four single nucleotide polymorphisms (SNP) from the SLC2A9 gene were genotyped in both groups (rs733175, rs6449213, rs1014290, and rs737267). ----- Results. There was a weak but significant association of all 4 SNPs and nephrolithiasis (P=0.029 for rs733175; P=0.006 for rs6449213; P=0.020 for rs1014290, and P=0.011 for rs737267). Logistic regression in an age- and sex-adjusted model suggested that genotype C/T for rs6449213 had odds ratio for nephrolithiasis of 2.89 (95% confidence interval 1.13-7.40). This SNP explained a total of 4.4% of nephrolithiasis variance. ----- Conclusion. Development of nephrolithiasis may be associated with SLC2A9 gene. Further studies are needed to clarify the role of SLC2A9 gene as a link between uric acid and nephrolithiasis.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatian Medical Journal
Numberingvol. 51, no. 1, pp. 48-53
p-ISSN0353-9504
DOIhttps://doi.org/10.3325/cmj.2010.51.48
URN:NBNurn:nbn:hr:105:386603
Publication2010-02-15
Document URLhttp://www.cmj.hr/2010/51/1/20162745.htm
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 11:31:42