prikaz prve stranice dokumenta Incidence of neurological complications in patients with native-valve infective endocarditis and cerebral microembolism: an open cohort study
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Scientific paper - Original scientific paper
Incidence of neurological complications in patients with native-valve infective endocarditis and cerebral microembolism: an open cohort study
Scandinavian Journal of Infectious Diseases, 41 (2009), 10; 708-713. https://doi.org/10.1080/00365540903146995
Lepur, Dragan; Baršić, Bruno

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Lepur, D. & Baršić, B. (2009). Incidence of neurological complications in patients with native-valve infective endocarditis and cerebral microembolism: an open cohort study. Scandinavian Journal of Infectious Diseases, 41. (10), 708-713. doi: 10.1080/00365540903146995

Lepur, Dragan and Bruno Baršić. "Incidence of neurological complications in patients with native-valve infective endocarditis and cerebral microembolism: an open cohort study." Scandinavian Journal of Infectious Diseases, vol. 41, no. 10, 2009, pp. 708-713. https://doi.org/10.1080/00365540903146995

Lepur, Dragan and Bruno Baršić. "Incidence of neurological complications in patients with native-valve infective endocarditis and cerebral microembolism: an open cohort study." Scandinavian Journal of Infectious Diseases 41, no. 10 (2009): 708-713. https://doi.org/10.1080/00365540903146995

Lepur, D. and Baršić, B. (2009) 'Incidence of neurological complications in patients with native-valve infective endocarditis and cerebral microembolism: an open cohort study', Scandinavian Journal of Infectious Diseases, 41(10), pp. 708-713. doi: 10.1080/00365540903146995

Lepur D, Baršić B. Incidence of neurological complications in patients with native-valve infective endocarditis and cerebral microembolism: an open cohort study. Scandinavian Journal of Infectious Diseases [Internet]. 2009 [cited 2024 May 21];41(10):708-713. doi: 10.1080/00365540903146995

D. Lepur and B. Baršić, "Incidence of neurological complications in patients with native-valve infective endocarditis and cerebral microembolism: an open cohort study", Scandinavian Journal of Infectious Diseases, vol. 41, no. 10, pp. 708-713, 2009. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:935890. [Accessed: 21 May 2024]

Metadata
Title (english)Incidence of neurological complications in patients with native-valve infective endocarditis and cerebral microembolism: an open cohort study
AuthorDragan Lepur
AuthorBruno Baršić
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The objective of this open cohort study was to assess the association between neurological complications in patients with definite native-valve infective endocarditis (IE) and cerebral microembolism (MES). MES detection was performed with 1-h, bilateral middle cerebral arteries (MCA) insonation using a transcranial Doppler ultrasound (TCD) machine. Thirty patients with definite native-valve IE were stratified into 2 groups based upon the presence of MES. The most striking difference between the 2 groups of patients was the incidence of clinically evident neurological complications. Neurological complications of IE occurred in 10 (83.3%) patients with positive MES and in 6 (33.3%) MES-negative patients (p=0.021). Ischaemic stroke was the most common complication, occurring in 11 of 16 patients, followed by meningitis in 4 patients and cerebritis in 1 patient. There was a trend towards greater in-hospital mortality in patients with recorded MES than in the MES-negative, although this was not statistically significant (33.3% vs 16.6%; p=0.392). Our results reveal a significant association between MES and neurological complications in patients with native-valve IE. TCD is a promising tool in predicting individual patient risk for neurological complications of IE.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleScandinavian Journal of Infectious Diseases
Numberingvol. 41, no. 10, pp. 708-713
p-ISSN0036-5548
DOIhttps://doi.org/10.1080/00365540903146995
URN:NBNurn:nbn:hr:105:935890
Publication2009
Document URLhttps://doi.org/10.1080/00365540903146995
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 11:51:25