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Scientific paper - Original scientific paper
Physical characteristics in the new model of the cerebrospinal fluid system
Collegium Antropologicum, 35 (2011), S. 1; 51-56. urn:nbn:hr:105:047138
Jurjević, Ivana; Radoš, Milan; Orešković, Janko; Prijić, Radovan; Tvrdeić, Ante; Klarica, Marijan

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Jurjević, I., Radoš, M., Orešković, J., Prijić, R., Tvrdeić, A. & Klarica, M. (2011). Physical characteristics in the new model of the cerebrospinal fluid system . Collegium Antropologicum, 35. (S. 1), 51-56. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:047138

Jurjević, Ivana, et al. "Physical characteristics in the new model of the cerebrospinal fluid system ." Collegium Antropologicum, vol. 35, no. S. 1, 2011, pp. 51-56. https://urn.nsk.hr/urn:nbn:hr:105:047138

Jurjević, Ivana, Milan Radoš, Janko Orešković, Radovan Prijić, Ante Tvrdeić and Marijan Klarica. "Physical characteristics in the new model of the cerebrospinal fluid system ." Collegium Antropologicum 35, no. S. 1 (2011): 51-56. https://urn.nsk.hr/urn:nbn:hr:105:047138

Jurjević, I., et al. (2011) 'Physical characteristics in the new model of the cerebrospinal fluid system ', Collegium Antropologicum, 35(S. 1), pp. 51-56. Available at: https://urn.nsk.hr/urn:nbn:hr:105:047138 (Accessed 23 November 2024)

Jurjević I, Radoš M, Orešković J, Prijić R, Tvrdeić A, Klarica M. Physical characteristics in the new model of the cerebrospinal fluid system . Collegium Antropologicum [Internet]. 2011 January [cited 2024 November 23];35(S. 1):51-56. Available at: https://urn.nsk.hr/urn:nbn:hr:105:047138

I. Jurjević, M. Radoš, J. Orešković, R. Prijić, A. Tvrdeić and M. Klarica, "Physical characteristics in the new model of the cerebrospinal fluid system ", Collegium Antropologicum, vol. 35, no. S. 1, pp. 51-56, January 2011. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:047138. [Accessed: 23 November 2024]

Metadata
Title (english)Physical characteristics in the new model of the cerebrospinal fluid system
Title (croatian)Fizikalne osobine novog modela cerebrospinalnog likvora
AuthorIvana Jurjević
AuthorMilan Radoš
AuthorJanko Orešković
AuthorRadovan Prijić
AuthorAnte Tvrdeić
AuthorMarijan Klarica
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
It is unknown which factors determine the changes in cerebrospinal fluid (CSF) pressure inside the craniospinal system during the changes of the body position. To test this, we have developed a new model of the CSF system, which by its biophysical characteristics and dimensions imitates the CSF system in cats. The results obtained on a model were compared to those in animals observed during changes of body position. A new model was constructed from two parts with different physical characteristics. The »cranial« part is developed from a plastic tube with unchangeable volume, while the »spinal« part is made of a rubber baloon, with modulus of elasticity similar to that of animal spinal dura. In upright position, in the »cranial« part of the model the negative pressure appears without any measurable changes in the fluid volume, while in »spinal« part the fluid pressure is positive. All of the observed changes are in accordance to the law of the fluid mechanics. Alterations of the CSF pressure in cats during the changes of the body position are not significantly different compared to those observed on our new model. This suggests that the CSF pressure changes are related to the fluid mechanics, and do not depend on CSF secretion and circulation. It seems that in all body positions the cranial volume of blood and CSF remains constant, which enables a good blood brain perfusion.
Abstract (croatian)
Nije poznato koji sve čimbenici uvjetuju promjene tlaka likvora unutar kraniospinalnog sustava pri promjeni položaja tijela. Kako bismo to ispitali izradili smo novi model likvorskog sustava koji svojim biofizičkim karakteristikama i dimenzijama imitira likvorski sustav u mačaka te usporedili rezultate dobivene na modelu i životinjama pri promjeni položaja iz horizontalnog u uspravni. Novi model je izrađen iz dva dijela. »Kranijski« dio je izrađen od plastične cijevi i ne može mijenjati svoj volumen, dok je »spinalni« dio izrađen od duguljastog gumenog balona sličnog elastičnog modula kao spinalna dura pa može mijenjati volumen u svakom segmentu. Pri uspravljanju modela u »kranijskom« dijelu dolazi do pojave negativnog tlaka bez promjene volumena tekućine unutar tog prostora, a u »spinalnom« dijelu tlak tekućine odgovara visini hidrostatskog tlaka što je u skladu s zakonom o mehanici fluida. Promjene tlaka likvora kod promjene položaja mačke ne razlikuju se od promjena tlaka tekućine opažene u modelu. To ukazuje kako su promjene tlaka likvora odvijaju u skladu s zakonom o mehanici fluida i ne ovise o sekreciji i cirkulaciji likvora.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium Antropologicum
Numberingvol. 35, no. S. 1, pp. 51-56
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:047138
Publication2011-01
Document URLhttps://hrcak.srce.hr/64040
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 11:59:26