prikaz prve stranice dokumenta Ekvivalent: Granulomatoza s poliangiitisom i lokaliziranim zahvaćanjem gornjega dišnoga sustava ‒ prikaz bolesnice
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professional thesis
Ekvivalent: Granulomatoza s poliangiitisom i lokaliziranim zahvaćanjem gornjega dišnoga sustava ‒ prikaz bolesnice
Zagreb: University of Zagreb, School of Medicine, 2022. urn:nbn:hr:105:378875
Marković, Ivan
University of Zagreb
School of Medicine

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Marković, I. (2022). Ekvivalent: Granulomatoza s poliangiitisom i lokaliziranim zahvaćanjem gornjega dišnoga sustava ‒ prikaz bolesnice (Professional thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:378875

Marković, Ivan. "Ekvivalent: Granulomatoza s poliangiitisom i lokaliziranim zahvaćanjem gornjega dišnoga sustava ‒ prikaz bolesnice." Professional thesis, University of Zagreb, School of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:105:378875

Marković, Ivan. "Ekvivalent: Granulomatoza s poliangiitisom i lokaliziranim zahvaćanjem gornjega dišnoga sustava ‒ prikaz bolesnice." Professional thesis, University of Zagreb, School of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:105:378875

Marković, I. (2022). 'Ekvivalent: Granulomatoza s poliangiitisom i lokaliziranim zahvaćanjem gornjega dišnoga sustava ‒ prikaz bolesnice', Professional thesis, University of Zagreb, School of Medicine, accessed 26 November 2024, https://urn.nsk.hr/urn:nbn:hr:105:378875

Marković I. Ekvivalent: Granulomatoza s poliangiitisom i lokaliziranim zahvaćanjem gornjega dišnoga sustava ‒ prikaz bolesnice [Professional thesis]. Zagreb: University of Zagreb, School of Medicine; 2022 [cited 2024 November 26] Available at: https://urn.nsk.hr/urn:nbn:hr:105:378875

I. Marković, "Ekvivalent: Granulomatoza s poliangiitisom i lokaliziranim zahvaćanjem gornjega dišnoga sustava ‒ prikaz bolesnice", Professional thesis, University of Zagreb, School of Medicine, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:105:378875

Metadata
TitleEkvivalent: Granulomatoza s poliangiitisom i lokaliziranim zahvaćanjem gornjega dišnoga sustava ‒ prikaz bolesnice
Title (english)Equivalent: Granulomatosis with polyangiitis (GPA) limited to upper respiratory tract – a case report
AuthorIvan Marković
MentorJadranka Morović-Vergles (mentor)
GranterUniversity of Zagreb
School of Medicine
Zagreb
Defense date and country2022-01-10, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Clinical Immunology
Abstract
Granulomatoza s poliangiitisom (Wegenerova granulomatoza) ubraja se u vaskulitise malih krvnih žila povezane s antineutrofilnim citoplazmatskim protutijelima. Najčešće su zahvaćeni gornji i donji dišni sustav te bubrezi. Obilježjan bolesti uključuju granulomatoznu upalu dišnog sustava i nekrotizirajući vaskulitis malih do srednje velikih krvnih žila. U većine je bolesnika pri postavljanju dijagnoze zahvaćeno više organskih sustava te mogu biti prisutni i opći simptomi, dok je u oko četvrtine bolesnika inicijalno prisutan lokalizirani oblik bolesti sa zahvaćanjem najčešće gornjega dišnog sustava ili pluća. U radu smo prikazali dvadesetjednogodišnju bolesnicu s kroničnim rinitisom, razvojem sedlaste deformacije nosa i subglotičnom stenozom traheje koja je hospitalizirana zbog inspiratornog stridora. Zbog respiratorne insuficijencije učinjena je hitna traheotomija. U bolesnice je dijagnosticirana granulomatoza s poliangiitisom ograničena na gornji dišni sustav. Liječenje glukokortikoidima i metotreksatom dovelo je do kliničkog poboljšanja.
Abstract (english)
Granulomatosis with polyangiitis (Wegener’s granulomatosis) is one of the anti-neutrophil cytoplasmic antibody-associated small vessel vasculitides. Upper and lower respiratory system and kidneys are most commonly affected. The disease is characterized by granulomatous inflammation of the respiratory tract and necrotizing vasculitis of small to medium-sized blood vessels. Most patients show involvement of more than one organ systems at the time of diagnosis, and constitutional symptoms may be present. In around a quarter of patients the disease is initially localised, with involvement of upper respiratory tract or lungs. We report a 21-year-old female patient with chronic rhinitis, saddle nose deformity and subglottic stenosis who presented with inspiratory stridor and impending respiratory failure. Initially, urgent tracheotomy was performed. The patient was diagnosed with granulomatosis with polyangiitis limited to upper respiratory tract. Treatment with glucocorticoids and methotrexate was followed by clinical improvement.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:378875
Study programmeTitle: Allergology and clinical immunology
Study programme type: university
Study level: postgraduate specialist
Academic / professional title: sveučilišni/a magistar/magistra alergologije i kliničke imunologije (sveučilišni/a magistar/magistra alergologije i kliničke imunologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-04-05 11:32:35