prikaz prve stranice dokumenta Enterobacter cloacae septicemia in a triple-cannula extracorporeal membrane oxygenation circulatory support treated with Seraph-100 Microbind affinity blood filter
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Scientific paper - Case study
Enterobacter cloacae septicemia in a triple-cannula extracorporeal membrane oxygenation circulatory support treated with Seraph-100 Microbind affinity blood filter
Croatian Medical Journal, 64 (2023), 4; 284-288. https://doi.org/10.3325/cmj.2023.64.284
Pavlov, Marin; Bodrožić Džakić Poljak, Tomislava; Pavlović, Nikola; Šestan Crnek, Sandra; Barić, Davor; Rudež, Igor

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Pavlov, M., Bodrožić Džakić Poljak, T., Pavlović, N., Šestan Crnek, S., Barić, D. & Rudež, I. (2023). Enterobacter cloacae septicemia in a triple-cannula extracorporeal membrane oxygenation circulatory support treated with Seraph-100 Microbind affinity blood filter. Croatian Medical Journal, 64. (4), 284-288. doi: 10.3325/cmj.2023.64.284

Pavlov, Marin, et al. "Enterobacter cloacae septicemia in a triple-cannula extracorporeal membrane oxygenation circulatory support treated with Seraph-100 Microbind affinity blood filter." Croatian Medical Journal, vol. 64, no. 4, 2023, pp. 284-288. https://doi.org/10.3325/cmj.2023.64.284

Pavlov, Marin, Tomislava Bodrožić Džakić Poljak, Nikola Pavlović, Sandra Šestan Crnek, Davor Barić and Igor Rudež. "Enterobacter cloacae septicemia in a triple-cannula extracorporeal membrane oxygenation circulatory support treated with Seraph-100 Microbind affinity blood filter." Croatian Medical Journal 64, no. 4 (2023): 284-288. https://doi.org/10.3325/cmj.2023.64.284

Pavlov, M., et al. (2023) 'Enterobacter cloacae septicemia in a triple-cannula extracorporeal membrane oxygenation circulatory support treated with Seraph-100 Microbind affinity blood filter', Croatian Medical Journal, 64(4), pp. 284-288. doi: 10.3325/cmj.2023.64.284

Pavlov M, Bodrožić Džakić Poljak T, Pavlović N, Šestan Crnek S, Barić D, Rudež I. Enterobacter cloacae septicemia in a triple-cannula extracorporeal membrane oxygenation circulatory support treated with Seraph-100 Microbind affinity blood filter. Croatian Medical Journal [Internet]. 2023 [cited 2024 November 05];64(4):284-288. doi: 10.3325/cmj.2023.64.284

M. Pavlov, T. Bodrožić Džakić Poljak, N. Pavlović, S. Šestan Crnek, D. Barić and I. Rudež, "Enterobacter cloacae septicemia in a triple-cannula extracorporeal membrane oxygenation circulatory support treated with Seraph-100 Microbind affinity blood filter", Croatian Medical Journal, vol. 64, no. 4, pp. 284-288, 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:707139. [Accessed: 05 November 2024]

Metadata
Title (english)Enterobacter cloacae septicemia in a triple-cannula extracorporeal membrane oxygenation circulatory support treated with Seraph-100 Microbind affinity blood filter
AuthorMarin Pavlov
AuthorTomislava Bodrožić Džakić Poljak
AuthorNikola Pavlović
AuthorSandra Šestan Crnek
AuthorDavor Barić
AuthorIgor Rudež
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Surgery)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Surgery
Abstract (english)
Bloodstream infections (BSI) are frequently encountered during extracorporeal membrane oxygenation (ECMO) support. Once septicemia is observed, treatment should be rapid, adequate, and multifaceted, particularly in advanced ECMO configurations. We report on a case of a 60-year-old male patient with acute-on-chronic heart failure due to ischemic cardiomyopathy. The treatment was complicated by cardiogenic shock requiring veno-arterial ECMO support, and, due to persistent pulmonary congestion, an upgrade with an additional left-atrial drainage cannula. After seven days of ECMO support, septicemia with shock ensued. Ex iuvantibus antibiotic treatment was started promptly. We wanted to minimize the likelihood of bacterial biofilm build-up requiring an exchange of the ECMO circuit and cannula, which was expected to be challenging. Therefore, we added a Seraph-100 Microbind affinity blood filter (providing blood purification with the potential for rapid bacterial clearance) to the ECMO circuit. Initial blood cultures tested positive for Enterobacter cloacae. Following a course of Seraph-100 treatment, bacteremia, septicemia, and shock resolved. There was no need for a circuit or cannula exchange. The additional eleven days of ECMO support were uneventful. The patient was successfully bridged to long-term mechanical circulatory support. We believe that the synergistic effect of early implementation of both broad-spectrum antibiotic treatment and blood purification with the potential for rapid bacterial clearance (such as the one provided with the Seraph-100 Microbind affinity blood filter) is crucial in BSI in patients receiving advanced ECMO.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatian Medical Journal
Numberingvol. 64, no. 4, pp. 284-288
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2023.64.284
URN:NBNurn:nbn:hr:105:707139
Publication2023
Document URLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10509680/
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) icon
Created on2024-04-09 09:03:15