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Scientific paper - Review paper
Tear Biomarkers and Alzheimer’s Disease
International Journal of Molecular Sciences, 24 (2023), 17; 13429. https://doi.org/10.3390/ijms241713429
Kaštelan, Snježana; Braš, Marijana; Pjevač, Neda; Bakija, Ivana; Tomić, Zora; Pjevač Keleminić, Nada; Gverović Antunica, Antonela

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Kaštelan, S., Braš, M., Pjevač, N., Bakija, I., Tomić, Z., Pjevač Keleminić, N. & Gverović Antunica, A. (2023). Tear Biomarkers and Alzheimer’s Disease. International Journal of Molecular Sciences, 24. (17). doi: 10.3390/ijms241713429

Kaštelan, Snježana, et al. "Tear Biomarkers and Alzheimer’s Disease." International Journal of Molecular Sciences, vol. 24, no. 17, 2023. https://doi.org/10.3390/ijms241713429

Kaštelan, Snježana, Marijana Braš, Neda Pjevač, Ivana Bakija, Zora Tomić, Nada Pjevač Keleminić and Antonela Gverović Antunica. "Tear Biomarkers and Alzheimer’s Disease." International Journal of Molecular Sciences 24, no. 17 (2023). https://doi.org/10.3390/ijms241713429

Kaštelan, S., et al. (2023) 'Tear Biomarkers and Alzheimer’s Disease', International Journal of Molecular Sciences, 24(17). doi: 10.3390/ijms241713429

Kaštelan S, Braš M, Pjevač N, Bakija I, Tomić Z, Pjevač Keleminić N, and sur.. Tear Biomarkers and Alzheimer’s Disease. International Journal of Molecular Sciences [Internet]. 2023 August 30 [cited 2024 November 04];24(17). doi: 10.3390/ijms241713429

S. Kaštelan, et al., "Tear Biomarkers and Alzheimer’s Disease", International Journal of Molecular Sciences, vol. 24, no. 17, August 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:237686. [Accessed: 04 November 2024]

Metadata
Title (english)Tear Biomarkers and Alzheimer’s Disease
AuthorSnježana Kaštelan
AuthorMarijana Braš
AuthorNeda Pjevač
AuthorIvana Bakija
AuthorZora Tomić
AuthorNada Pjevač Keleminić
AuthorAntonela Gverović Antunica
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Medical Statistics, Epidemiology and Medical Informatics)
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Family Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Public Health and Health Care
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Public Health and Health Care
Family Medicine
Abstract (english)
Alzheimer’s disease (AD) is an age-related progressive neurodegenerative brain disorder that represents the most common type of dementia. It poses a significant diagnostic challenge that requires timely recognition and treatment. Currently, there is no effective therapy for AD; however, certain medications may slow down its progression. The discovery of AD biomarkers, namely, magnetic resonance imaging, positron emission tomography and cerebrospinal fluid molecules (amyloid-β and tau) has advanced our understanding of this disease and has been crucial for identifying early neuropathologic changes prior to clinical changes and cognitive decline. The close interrelationship between the eye and the brain suggests that tears could be an interesting source of biomarkers for AD; however, studies in this area are limited. The identification of biomarkers in tears will enable the development of cost-effective, non-invasive methods of screening, diagnosis and disease monitoring. In order to use tears as a standard method for early and non-invasive diagnosis of AD, future studies need to be conducted on a larger scale.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleInternational Journal of Molecular Sciences
Numberingvol. 24, no. 17, 13429
e-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms241713429
URN:NBNurn:nbn:hr:105:237686
Publication2023-08-30
Document URLhttps://www.mdpi.com/1422-0067/24/17/13429
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2024-06-14 09:34:03