prikaz prve stranice dokumenta Analiza senzitizacije na uobičajene aeroalergene i korelacija s kliničkim simptomima u odrasloj populaciji
  Download
PDF 2.41 MB
master's thesis
Analiza senzitizacije na uobičajene aeroalergene i korelacija s kliničkim simptomima u odrasloj populaciji
Zagreb: University of Zagreb, School of Medicine, 2024. urn:nbn:hr:105:513465
Zdilar, Ana Marija
University of Zagreb
School of Medicine
Department of Internal Medicine

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Zdilar, A. M. (2024). Analiza senzitizacije na uobičajene aeroalergene i korelacija s kliničkim simptomima u odrasloj populaciji (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:513465

Zdilar, Ana Marija. "Analiza senzitizacije na uobičajene aeroalergene i korelacija s kliničkim simptomima u odrasloj populaciji." Master's thesis, University of Zagreb, School of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:105:513465

Zdilar, Ana Marija. "Analiza senzitizacije na uobičajene aeroalergene i korelacija s kliničkim simptomima u odrasloj populaciji." Master's thesis, University of Zagreb, School of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:105:513465

Zdilar, A. M. (2024). 'Analiza senzitizacije na uobičajene aeroalergene i korelacija s kliničkim simptomima u odrasloj populaciji', Master's thesis, University of Zagreb, School of Medicine, accessed 11 August 2024, https://urn.nsk.hr/urn:nbn:hr:105:513465

Zdilar AM. Analiza senzitizacije na uobičajene aeroalergene i korelacija s kliničkim simptomima u odrasloj populaciji [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2024 [cited 2024 August 11] Available at: https://urn.nsk.hr/urn:nbn:hr:105:513465

A. M. Zdilar, "Analiza senzitizacije na uobičajene aeroalergene i korelacija s kliničkim simptomima u odrasloj populaciji", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:105:513465

Metadata
TitleAnaliza senzitizacije na uobičajene aeroalergene i korelacija s kliničkim simptomima u odrasloj populaciji
Title (english)Analysis of sensitization to common aeroallergens and correlation with clinical symptoms in the adult population
AuthorAna Marija Zdilar
MentorMarina Ikić Matijašević (mentor)
Committee memberJoško Mitrović (predsjednik povjerenstva)
Committee memberMarija Bakula (član povjerenstva)
Committee memberMarina Ikić Matijašević (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Zagreb
Defense date and country2024-07-12, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
Uvod. Alergije su jedne od najčešćih kroničnih bolesti današnjice koje utječu na svakodnevni život više od 60 milijuna ljudi u Europi. Procjenjuje se da između 30 i 40% osoba u svijetu boluje od jedne ili više alergijskih bolesti te da je broj oboljelih u stalnom porastu. Cilj istraživanja. Odrediti dominantni aeroalergen u našoj populaciji, obrazac senzitizacije na najčešće aeroalergene (monosenzitizacija ili polisenzitizacija) i odrediti simptome alergije u odrasloj senzibiliziranoj populaciji te navedeno usporediti s podacima dostupnim u literaturi. Metode. Ovo istraživanje provedeno je od siječnja 2024. do svibnja 2024. godine u Kliničkoj bolnici Sveti Duh u Ambulanti za alergološku dijagnostiku. U istraživanju je sudjelovalo ukupno 100 bolesnika starijih od 18 godina koji su ispunili upitnik o alergijskim simptomima i bolestima te im je proveden kožni ubodni test na petnaest inhalacijskih alergena. Rezultati. U istraživanju su analizirana 83 pacijenta starija od 18 godina, od kojih je 78% bilo žena, s prosječnom dobi od 38 godina. Rezultati su pokazali da je 56.6% ispitanika imalo pozitivne kožne ubodne testove na barem jedan aeroalergen, pri čemu su najčešći bili ambrozija, pelud trava, grinje i lijeska. Utvrđeno je da su pacijenti najčešće polisenzibilizirani, što je u skladu s drugim istraživanjima. Najčešći simptomi kod ispitanika bili su kihanje, curenje i svrbež nosa, dok je 43.4% ispitanika već imalo dijagnozu alergijske bolesti, pri čemu su najčešće bile alergijski rinitis i astma. Analiza je pokazala da ispitanici s pozitivnim kožnim testom češće imaju obiteljsku anamnezu atopijskih bolesti te da češće prijavljuju alergiju na hranu. Zaključak. Ovo istraživanje naglašava važnost cjelovitog pristupa u dijagnostici i liječenju alergijskih bolesti obzirom na visoku prevalenciju senzibilizacije na inhalacijske alergene i simptoma alergije u našoj populaciji.
Abstract (english)
Introduction. Allergies are among the most common chronic diseases today, affecting the daily lives of over 60 million people in Europe alone. It is estimated that 30-40% of the global population is afflicted by one or more allergic diseases, with the prevalence showing a consistent upward trend. Aim. To determine the dominant aeroallergen in our population, the pattern of sensitization to the most common aeroallergens (monosensitization or polysensitization), and to identify allergy symptoms in the adult sensitized population. Methods. This study was conducted from January 2024 to May 2024 at the Clinical Hospital Sveti Duh in the Allergy Diagnostic Outpatient Clinic. A total of 100 patients over 18 years of age participated in the study, completing a questionnaire on allergic symptoms and diseases, and underwent a skin prick test for fifteen aeroallergens. Results. The study analysed 83 patients over 18 years of age, of whom 78% were women, with an average age of 38 years. The results showed that 56.6% of participants had positive skin prick tests for at least one aeroallergen, with the most common being ragweed, grass pollen, dust mites, and hazelnut. It was found that patients were most commonly polysensitized, consistent with other studies. The most common symptoms among participants were sneezing, runny nose, and nasal itching, while 43.4% of participants already had a diagnosis of allergic disease, most commonly allergic rhinitis and asthma. The analysis showed that participants with positive skin prick tests more frequently had a family history of atopic diseases and were more often allergic to food. Conclusion. This study emphasizes the importance of a comprehensive approach to the diagnosis and treatment of allergic diseases, considering the high prevalence of sensitization to aeroallergens and allergy symptoms in our population.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:513465
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-07-01 20:39:51