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master's thesis
Zastupljenost karotidne stenoze u bolesnika s akutnim ishemijskim moždanim udarom
Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. urn:nbn:hr:152:090948
Radičević, Zlatka
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

Institutional repository: Repository of the Faculty of Medicine Osijek

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Radičević, Z. (2019). Zastupljenost karotidne stenoze u bolesnika s akutnim ishemijskim moždanim udarom (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:090948

Radičević, Zlatka. "Zastupljenost karotidne stenoze u bolesnika s akutnim ishemijskim moždanim udarom." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. https://urn.nsk.hr/urn:nbn:hr:152:090948

Radičević, Zlatka. "Zastupljenost karotidne stenoze u bolesnika s akutnim ishemijskim moždanim udarom." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. https://urn.nsk.hr/urn:nbn:hr:152:090948

Radičević, Z. (2019). 'Zastupljenost karotidne stenoze u bolesnika s akutnim ishemijskim moždanim udarom', Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 22 November 2024, https://urn.nsk.hr/urn:nbn:hr:152:090948

Radičević Z. Zastupljenost karotidne stenoze u bolesnika s akutnim ishemijskim moždanim udarom [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2019 [cited 2024 November 22] Available at: https://urn.nsk.hr/urn:nbn:hr:152:090948

Z. Radičević, "Zastupljenost karotidne stenoze u bolesnika s akutnim ishemijskim moždanim udarom", Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:152:090948

Metadata
TitleZastupljenost karotidne stenoze u bolesnika s akutnim ishemijskim moždanim udarom
Title (english)The Presence of Carotid Stenosis in Patients with Acute Ischemic Stroke
AuthorZlatka Radičević
MentorDragutin Kadojić (mentor)
Committee memberDavor Jančuljak (predsjednik povjerenstva)
Committee memberIvanka Štenc Bradvica (član povjerenstva)
Committee memberDragutin Kadojić (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2019-07-05, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Abstract
Cilj istraživanja: Ispitati zastupljenost bolesnika koji imaju karotidnu aterosklerotsku bolest, zastupljenost glavnih čimbenika rizika za moždani udar te ispitati vrstu i stupanj aterosklerotskih stenotskih promjena u različitim podvrstama akutnog ishemijskog moždanog udara (IMU). Nacrt studije: studija je bila presječena povijesnim podatcima. Ispitanici i metode: Ispitalo se 100 bolesnika s akutnim IMU-om. Bilježili su se podatci o dobi i spolu bolesnika, podatci o glavnim čimbenicima rizika za nastanak akutnog IMU-a, podatci o podvrsti IMU-a prema The Trial of Org 10172 in Acute Stroke Treatment klasifikaciji te su se bilježili nalazi color dopplera karotidnih i vertebralnih arterija. Rezultati: Istraživanje pokazuje visok udjel karotidne aterosklerotske bolesti (97 %) u bolesnika s akutnim IMU-om. Stenoza karotidne arterije bila je zastupljena u 62 % ispitanika, od čega je najveći broj imao početnu stenozu, a najmanja je bila zastupljenost hemodinamski značajne stenoze. Najviša zastupljenost karotidne stenoze i okluzije bila je u bolesnika s IMU-om velikih krvnih žila, a lakši stupanj aterosklerotske bolesti (plakovi i početna stenoza) u bolesnika s IMU-om malih krvnih žila i kardioembolijskom IMU-om. U bolesnika s hiperlipidemijom pronađena je povećana učestalost mješovitih te nešto manja tvrdih aterosklerotskih plakova. Zaključak: Provedeno istraživanje pokazuje izrazito visoku zastupljenost karotidne stenoze i aterosklerotskih plakova u bolesnika s akutnim IMU-om, daje korisne informacije o etiopatogenezi i patofiziologiji ove bolesti i ukazuje na važnost color dopplera karotidnih arterija u liječenju i prevenciji IMU-a.
Abstract (english)
Objective: The aim of the study was to determine the prevalence of carotid artery stenosis, the prevalence of acute ischemic stroke risk factors, and to determine the stage of carotid atherosclerosis in stroke subtypes in acute ischemic stroke patients. Study design: The study was designed as a cross sectional study with data extracted from patients’ history. Participants and methods: The study included 100 patients suffering from acute ischemic stroke. The data observed included age, sex, and risk factors for stroke. Stroke subtype was identified by The Trial of Org 10172 in Acute Stroke Treatment classification. Color Doppler evaluation of carotid and vertebral artery were recorded as well. Results: The study indicated high prevalence of carotid atherosclerotic disease (97 %) in patients with acute ischemic stroke. Carotid artery stenosis was found in 62 % of the patients. Mild stenosis was the most common, while severe stenosis was the least prevalent. Patients with large-artery atherosclerosis displayed highest prevalence of carotid stenosis and occlusion, while patients with cardioembolism and small-artery occlusion had highest prevalence of initial stage of carotid atherosclerotic disease. Positive correlation was found between hyperlipidemia and echogenic and calcified atherosclerotic plaques. Conclusion: Conducted study leads to better understanding of etiology and pathophysiology of acute ischemic stroke and emphasizes the importance of color Doppler evaluation of carotid and vertebral arteries in acute ischemic stroke patients and in stroke prevention.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:090948
Study programmeTitle: University Graduate Studies
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-07-31 10:22:20