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master's thesis
Utjecaj hiperbarične oksigenacije na plazmatsku razinu angiotenzina II kod zdravih Sprague- Dawley štakora
Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. urn:nbn:hr:152:966956
Begović, Maja
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

Institutional repository: Repository of the Faculty of Medicine Osijek

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Begović, M. (2019). Utjecaj hiperbarične oksigenacije na plazmatsku razinu angiotenzina II kod zdravih Sprague- Dawley štakora (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:966956

Begović, Maja. "Utjecaj hiperbarične oksigenacije na plazmatsku razinu angiotenzina II kod zdravih Sprague- Dawley štakora." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. https://urn.nsk.hr/urn:nbn:hr:152:966956

Begović, Maja. "Utjecaj hiperbarične oksigenacije na plazmatsku razinu angiotenzina II kod zdravih Sprague- Dawley štakora." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. https://urn.nsk.hr/urn:nbn:hr:152:966956

Begović, M. (2019). 'Utjecaj hiperbarične oksigenacije na plazmatsku razinu angiotenzina II kod zdravih Sprague- Dawley štakora', Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 25 November 2024, https://urn.nsk.hr/urn:nbn:hr:152:966956

Begović M. Utjecaj hiperbarične oksigenacije na plazmatsku razinu angiotenzina II kod zdravih Sprague- Dawley štakora [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2019 [cited 2024 November 25] Available at: https://urn.nsk.hr/urn:nbn:hr:152:966956

M. Begović, "Utjecaj hiperbarične oksigenacije na plazmatsku razinu angiotenzina II kod zdravih Sprague- Dawley štakora", Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:152:966956

Metadata
TitleUtjecaj hiperbarične oksigenacije na plazmatsku razinu angiotenzina II kod zdravih Sprague- Dawley štakora
Title (english)The effect of hyperbaric oxygenation on plasma angiotensin II levels in healthy Sprague- Dawley rats Kratki opis
AuthorMaja Begović
MentorAleksandar Kibel (mentor)
Committee memberAnita Matić (predsjednik povjerenstva)
Committee memberInes Drenjančević (član povjerenstva)
Committee memberAleksandar Kibel (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2019-09-24, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Neuroscience
Abstract
Cilj istraživanja: Cilj je ovog istraživanja ispitati utjecaj hiperbarične oksigenacije na plazmatsku razinu angiotenzina II kod zdravih Sprague-Dawley štakora. Nacrt studije: Istraživanje je eksperimentalna (pokusna) studija. Materijali i metode: U istraživanje su bili uključeni zdravi laboratorijski Sprague-Dawley štakori muškog spola, podijeljeni u dvije skupine: Kontrolna skupina (N = 8) - zdravi netretirani štakori te HBO skupina (N = 8) - štakori izloženi intermitentnoj hiperbaričnoj oksigenaciji (četiri dana po dva sata, pod tlakom od 2 bara). Nakon anestezije, štakori su dekapitirani te su prikupljeni uzorci krvi i centrifugirani kako bi se dobila plazma. Iz uzoraka plazme spektrofotometrijskom metodom ELISA određena je koncentracija angiotenzina II. Rezultati: Nisu utvrđene statistički značajne razlike u koncentraciji ANG II između kontrolne i HBO skupine. Zaključak: Hiperbarična oksigenacija, u okviru specifičnog korištenog protokola, ne mijenja značajno razinu angiotenzina II u plazmi zdravih muških Sprague-Dawley štakora.
Abstract (english)
Objective: The objective of this study is to determine the effect of hyperbaric oxygenation on plasma angiotensin II levels in healthy Sprague-Dawley rats. Study design: The study is structured as an experimental study. Material and methods: The study included healthy male Sprague-Dawley lab rats, divided into two groups: Control group (N = 8) - healthy untreated rats and HBOT group (N = 8) - rats exposed to intermittent hyperbaric oxygenation (4 days at 2 hours, under pressure of 2 bar). After anesthesia, the rats were decapitated and blood samples were collected and centrifuged to obtain plasma. Plasma samples were determined by the spectrophotometric method ELISA for concentrations of angiotensin II. Results: No statistically significant difference in ANG II concentration were found between the control and HBO groups. Conclusion: Hyperbaric oxygenation, in the context of the specific protocol that has been used, does not significantly alter plasma angiotensin II levels in healthy male Sprague-Dawley rats.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:966956
Study programmeTitle: University graduate study
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra medicinsko laboratorijske dijagnostike (magistar/magistra medicinsko laboratorijske dijagnostike)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-12-05 12:38:14