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master's thesis
Značenje nalaza atipičnih pločastih stanica u Papa razmazima adolescentica i mladih žena
Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2020. urn:nbn:hr:152:078394
Križić, Katarina
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

Institutional repository: Repository of the Faculty of Medicine Osijek

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Križić, K. (2020). Značenje nalaza atipičnih pločastih stanica u Papa razmazima adolescentica i mladih žena (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:078394

Križić, Katarina. "Značenje nalaza atipičnih pločastih stanica u Papa razmazima adolescentica i mladih žena." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2020. https://urn.nsk.hr/urn:nbn:hr:152:078394

Križić, Katarina. "Značenje nalaza atipičnih pločastih stanica u Papa razmazima adolescentica i mladih žena." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2020. https://urn.nsk.hr/urn:nbn:hr:152:078394

Križić, K. (2020). 'Značenje nalaza atipičnih pločastih stanica u Papa razmazima adolescentica i mladih žena', Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 28 December 2024, https://urn.nsk.hr/urn:nbn:hr:152:078394

Križić K. Značenje nalaza atipičnih pločastih stanica u Papa razmazima adolescentica i mladih žena [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2020 [cited 2024 December 28] Available at: https://urn.nsk.hr/urn:nbn:hr:152:078394

K. Križić, "Značenje nalaza atipičnih pločastih stanica u Papa razmazima adolescentica i mladih žena", Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:152:078394

Metadata
TitleZnačenje nalaza atipičnih pločastih stanica u Papa razmazima adolescentica i mladih žena
Title (english)Significance of atypical squamous cell findings in Pap smears of adolescents and young women
AuthorKatarina Križić
MentorBranka Lončar (mentor)
Committee memberMilanka Mrčela (predsjednik povjerenstva)
Committee memberZlatko Topolovec (član povjerenstva)
Committee memberBranka Lončar (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2020-08-24, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract
CILJ ISTRAŽIVANJA: Ispitati značenje citološkoga nalaza atipičnih pločastih stanica; ne može se isključiti skvamozna intraepitelna lezija visokoga stupnja (ASC-H) u adolescentica i mladih žena (dobi od 18 do 30 godina). NACRT STUDIJE: Presječna studija. ISPITANICE I METODE: U istraživanje je uključeno 55 ispitanica u dobi od 18 do 30 godina kod kojih je u Kliničkom zavodu za kliničku citologiju KBC-a Osijek u razdoblju od 2013. do kraja 2018. godine izvršen citološki pregled VCE razmaza i postavljena dijagnoza ASC-H te su citološki praćene je li učinjena patohistološka verifikacija promjene vrata maternice. REZULTATI: Udio ASC-H nalaza ispitanica u dobi do 30 godina iznosio je 0,25 %. Tijekom citološkog praćenja (6, 12, 18 i 24 mjeseca) nisu uočene značajne razlike citoloških nalaza u odnosu na dob. Dijagnostička biopsija učinjena je kod 35 (64 %) ispitanica, konizacija kod njih 13 (24 %), a LETZ kod 7 (13 %). Konizaciju značajnije nisu imale nulipare. Patohistološkom analizom tkiva dobivenoga konizacijom kod 13 (24 %) ispitanica, koje su većinom (12/13) starije od 25 godina, potvrđena je prethodna biopsija HSIL (≥ CIN2). Usporedbom citološkoga i patohistološkoga nalaza, ustanovili smo učestalost nalaza ≥ CIN2 od 63,6 %. PPV je pokazala relativno visoku vrijednost od 83,33 %. ZAKLJUČAK: Pojavnost ASC-H nalaza u žena u dobi od 18 do 30 godina nije učestala, iznosi svega 0,25 %, a povezana je sa značajnom patologijom vrata maternice.
Abstract (english)
OBJECTIVES: To examine the significance of cytological findings of atypical squamous cells - cannot exclude high grade squamous intraepithelial lesion (ASC-H) in adolescents and young women (18 – 30 years of age). STUDY DESIGN: Cross-sectional study PARTICIPANTS AND METHODS: The study included 55 subjects 18 – 30 years of age. In the Clinical Institute of Clinical Cytology KBC Osijek, in the period from 2013 to the end of 2018, a cytological examination of VCE smears was performed, the subjects were diagnosed with ASC-H and were cytologically monitored or pathohistological verification of cervical changes was performed. RESULTS: The share of ASC-H findings of respondents under the age of 30 was 0.25 %. During a cytological follow-up (6, 12, 18 and 24 months), no significant differences in the cytological findings were recorded with respect to the subjects' age. A diagnostic biopsy was performed in 35 (64 %) subjects, conization in 13 (24 %), and LETZ in 7 (13 %). Nullipares did not have significant conization. A pathohistological analysis of tissue was conducted by conization in 13 (24 %) subjects, most of whom (12/13) are older than 25 years of age, which confirmed a previous biopsy HSIL (≥ CIN2). By comparing the cytological and pathohistological findings, we found the frequency of ≥ CIN2 findings of 63.6 %. PPV showed a relatively high value of 83.33 %. CONCLUSION: The incidence of ASC-H findings in women 18 – 30 years of age is not frequent; it is only 0,25 %, and is associated with a significant pathology of the cervix.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:078394
Study programmeTitle: University Graduate Studies
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2022-10-07 11:29:36