OBJECTIVE: Primary objective of this work was to question level and frequency of associated symptoms in patients with migraine headache. The specific aim was to question the correlation between associated symptoms and clinical features of the headache and to question the effect of associated symptoms in migraine attack on patients' quality of life. STUDY DESIGN: This is a cross-sectional study. PARTICIPANTS AND METHODS: The study included 30 participants suffering from migraines who were being treated at the Headache Clinic of the Neurology Department of the University Hospital Centre Osijek. An anonymous questionnaire specifically designed for this study and SF - 36 ( Short Form Health Survey 36) were the research tools used for this study. RESULTS: The most common associated symptom in migraine is phonophobia, which occurs very often or always in 91 % of the participants, while to that extent photophobia occured in 84 % of the participants, nausea and vomiting in 67 %, osmophobia in 47 % of the participants. The correlation between the frequency of associated symptoms and clinical features of the headache is not significant. In the SF-36 questionnaire, highest for the quality of life is rated the area of physical functioning, median 75 (interquartile range 45 – 95). There is a negative significant correlation between phonophobia and domain role limitations due to physical health (Rho = -0,385). Social functioning is worse if fatigue is more frequent (Rho = -0,401). CONCLUSION: The most common associated symptom in migraine headache attack is phonophobia. Differences in the frequency of associated symptoms relative to clinical features features of headache are not significant. While phonophobia and fatigue affect the domain of role limitations due the physical health and domain of social functioning, other associated symptoms have no impact on particular domains of quality of life.