Abstract | CILJ ISTRAŽIVANJA: Ispitati pojavnost patoloških promjena prilikom kolonoskopije kod osoba pozitivnih na hemokult testu te ispitati razliku u zastupljenosti malignih u odnosu na nemaligne patološke pojave. Prikazati raspodjelu pojavnosti patoloških promjena s obzirom na godinu otkrivanja (2015.-2019.). Ispitati postoji li povezanost rezultata kolonoskopije s dobi i spolom. NACRT STUDIJE: Presječna studija ISPITANICE I METODE: U istraživanje su bile uključene osobe koje su bile pozitivne na guaiac testu na nevidljivo krvarenje i obavljena im je kolonoskopija u okviru Nacionalnog programa ranog otkrivanja raka debelog crijeva od 2015. do 2019. godine u Osječko-baranjskoj županiji. Broj ispitanika bio je 478. Prikupljali su se podatci iz medicinske dokumentacije Nastavnog zavoda za javno zdravstvo Osječko-baranjske županije. Bilježili su se dob, spol i vrsta patološke pojave nakon kolonoskopije. REZULTATI: Istraživanje je provedeno na 478 ispitanika. Najviše ispitanika, njih 110, testirano je tijekom 2017. godine, dok je najmanji broj ispitanika, njih 66, testirano tijekom 2018. godine. Nakon obavljene kolonoskopije kod 36 (7,5 %) ispitanika otkrivene su maligne promjene. Uredan nalaz kolonoskopije imala su 42 (8,8 %) ispitanika. Najučestalija benigna promjena bili su polipi kod 230 (48,1 %) ispitanika, a hemoroidi kod 104 (21,8 %) ispitanika. Kolitis ima 16 (3,3 %) ispitanika, a divertikulozu 43 (9 %) ispitanika. S obzirom na spol 194 (40,6 %) ispitanika su bili muškarci, a 284 (59,4 %) su bile žene. Najveća učestalost malignih promjena pokazala se u dobi od 60 – 64 i od 70 – 75 godina. ZAKLJUČAK: U razdoblju 2015.-2019. godine u Osječko-baranjskoj županiji odaziv na testiranje u sklopu Nacionalnog programa ranog otkrivanja raka debelog crijeva je bio 21 %. Od ukupnog broja ispitanika (478) njih 42 (8,8 %) je imalo uredan nalaz kolonoskopije, a kod njih 36 (7,5 %) otkrivene su maligne promjene. Najveći broj pacijenata, 230 (48,1 %), je imao polipe kolona. Ostale benigne promjene bile su hemoroidi, divertikuloza i kolitisi. Uočena je značajna povezanost rezultata kolonoskopije s dobi. |
Abstract (english) | OBJECTIVES: Examine the occurrence of pathological changes during colonoscopy in Hemoccult test positive patients as well as examine the difference in distribution of malignant as compared to benign pathological changes. Present the distribution of occurrence of pathological changes due to the year of their detection (2015-2019). In addition, examine the possibility of correlation of colonoscopy results with variables such as age and sex. STUDY DESIGN: Cross-sectional study PARTICIPANTS AND METHODS: The study included subjects who were positive in guaiac test for hidden blood in a stool sample and colonoscopy was done in the frame of the National Program of Early Detection of Colon Cancer from 2015 to 2019 in Osijek-Baranja County. The total number of the subjects was 478. All medical data were collected from the medical records of the Teaching Institute of Public Health, Osijek -Baranja County. The variables such as age, sex and the types of the pathological changes found after colonoscopy were recorded. RESULTS: The study included 478 subjects. The greatest number of subjects, 110 of them, were tested during the year 2017, while the least number of subjects, 66 of them, were tested in 2018. After colonoscopy in 36 (7,5 %) subjects malignant changes were detected. In 42 (8,8 %) subjects colonoscopy test was negative. The most common benign changes in 230 (48,1 %) subjects were polyps, whereas in 104 (21,8 %) cases, the changes were hemorrhoids. Colitis was present in 16 (3,3 %) and diverticulitis was detected in 43 (9 %) cases. Due to sex, out of 478 tested subjects, 194 (40,6 %) subjects were men and 284 (59,4 %) were women. The highest frequency of malignant changes refers to two age groups; 60-64 and 70-75. CONCLUSION: Within the period between 2015-2019, the response to the testing in the frame of the National Program of Early Detection of Colon Cancer in Osijek-Baranja County was only 21 %. Out of 478 data subjects, 42 (8,8 %) of them had colonoscopy tests negative. In 36 (7,5 %) cases, malignant changes were found. The greatest number of subjects, 230 (48,1 %) of them, had polyps. The other benign changes included hemerrhoids, diverticulitis and colitis. The study showed a significant correlation between colonoscopy results and age factor. |