Objectives: The aim of this study was to successfully examine the intra-articular applications of methylprednisolone acetate in the treatment of hip OA in men and women by comparing the clinical picture before and after the procedure. Performance will be monitored using the VAS pain scale before and after drug administration. Study Design: The research was organized as a cross-sectional study. 17 patients were included, of which 8 were women and 9 were men. Patients and Methods: Subjects in this study are patients treated with methylprednisolone acetate for osteoarthritis of the hip of the first 3 stages in the Department of Orthopedics KBC Osijek during the last six months, in which, in addition to clinical examination and questionnaire, radiological diagnosis of the joint before the procedure has been done as well. From the available medical documentation of 17 patiens, general data on age, location, and functional findings of the diseased hip joint before and after surgery will be processed. Results: According to the results of the research, the share of osteoarthritis of the hip is equal in both sexes and in both localizations. Regarding the degree of the disease, the majority of patients are with the third degree, 9/17 of them; while the least are those with fourth degree, 3/17 of them. The success of methylprednisolone acetate is supported by pre- and post-drug statistics, monitored using the VAS pain rating scale. A significant reduction in pain was observed, as the initial median was 8 (interquartile range 7 - 9) and the final 3 (interquartile range 3 - 4). Conclusion: Significant pain reduction was achieved by intraarticular application of methylprednisolone acetate in hip OA.