Abstract | Cilj istraživanja: Ciljevi ovoga istraživanja bili su ispitati postoji li razlika u kliničkom nalazu
lezije dobivene koronarografijom i OCT-om, ispitati povezanost nalaza OCT-a u donošenju
odluka o dodatnoj optimizaciji PCI, ispitati povezanost nalaza OCT-a u dodatnoj procjeni
značajnosti lezije kod višežilne koronarne bolesti predviđene za kardiokirurško liječenje, te
ispitati postoji li povezanost između dijastoličke disfunkcije i veće učestalosti neadekvatne PCI
koja zahtjeva dodatnu optimizaciju na temelju OCT-a.
Ustroj studije: Presječno istraživanje s povijesnim podacima.
Ispitanici i metode: U studiju su bili uključeni pacijenti kojima je rađen OCT na Zavodu za
bolesti srca i krvnih žila Kliničkog bolničkog centra Osijek od 2021. do 2023. godine.
Rezultati: Istraživanje je provedeno na 62 pacijenta, medijana dobi od 67 godina. Najčešća
lokacija lezije je LAD u 52 (84 %) slučajeva. Čak 39 ispitanika (63 %) zahtjevalo je dodatnu
optimizaciju. Preporuku za kardiokirurški konzilij na temelju OCT-a imaju tri (5 %) bolesnika.
Značajno je povećanje duljine LAD (Wilcoxonov test, P < 0,001), Lcx (Wilcoxonov test,
P < 0,001) i RCA (Wilcoxonov test, P = 0,006) izmjerene OCT-om u odnosu na
koronarografiju. S obzirom na proksimalnu širinu, značajno su više vrijednosti proksimalne
širine LAD (Wilcoxonov test, P < 0,001) i proksimalne širine RCA (Wilcoxonov test,
P = 0,03).
Zaključak: Provedeno istraživanje pokazalo je važnu ulogu OCT-a u kliničkoj praksi, kod
detaljne procjene lezija na koronarnim arterijama, vođenju PCI-je te u procjeni dodatne
optimizaciji u pacijenata s koronarnom bolesti. |
Abstract (english) | Objectives: The objectives of this study were to examine whether there is a difference in the
clinical findings of the lesion obtained by coronary angiography and OCT, to examine the
association of OCT findings in the decision-making on additional optimization of PCI, to
examine the association of OCT findings in the additional assessment of the significance of the
lesion in multivessel coronary disease predicted for cardiac surgical treatment, and to examine
whether there is an association between diastolic dysfunction and a higher frequency of
inadequate PCI that requires additional optimization based on OCT.
Study design: Cross-sectional survey with historical data
Participants and methods: The study included patients who underwent OCT at the
Department of Cardiovascular Diseases of the Osijek Clinical Hospital Center from 2021 to
2023.
Results: The research was conducted on 62 patients, median age 67 years. The most common
location of the lesion is the LAD in 52 (84%) cases. 39 respondents (63%) requested additional
optimization. Three (5%) patients have a recommendation for cardiosurgical consultation based
on OCT. There was a significant increase in the length of LAD (Wilcoxon test, P < 0.001), Lcx
(Wilcoxon test, P < 0.001) and RCA (Wilcoxon test, P = 0.006) measured by OCT compared
to coronary angiography. Regarding the proximal width, the values of the proximal width of
the LAD (Wilcoxon test, P < 0.001) and the proximal width of the RCA (Wilcoxon test, P =
0.03) were significantly higher.
Conclusion: The conducted research showed the important role of OCT in clinical practice, in
the detailed assessment of lesions on the coronary arteries, in the management of PCI, and in
the assessment of additional optimization in patients with coronary disease. |