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master's thesis
Utjecaj specifične profilaktičke terapije migrene na pojavnost nebolnih simptoma migrene bez aure i na kvalitetu života u bolesnika s migrenom
Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2024. urn:nbn:hr:152:701942
Jakobović, Ružica
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

Institutional repository: Repository of the Faculty of Medicine Osijek

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Jakobović, R. (2024). Utjecaj specifične profilaktičke terapije migrene na pojavnost nebolnih simptoma migrene bez aure i na kvalitetu života u bolesnika s migrenom (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:701942

Jakobović, Ružica. "Utjecaj specifične profilaktičke terapije migrene na pojavnost nebolnih simptoma migrene bez aure i na kvalitetu života u bolesnika s migrenom." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2024. https://urn.nsk.hr/urn:nbn:hr:152:701942

Jakobović, Ružica. "Utjecaj specifične profilaktičke terapije migrene na pojavnost nebolnih simptoma migrene bez aure i na kvalitetu života u bolesnika s migrenom." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2024. https://urn.nsk.hr/urn:nbn:hr:152:701942

Jakobović, R. (2024). 'Utjecaj specifične profilaktičke terapije migrene na pojavnost nebolnih simptoma migrene bez aure i na kvalitetu života u bolesnika s migrenom', Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 22 November 2024, https://urn.nsk.hr/urn:nbn:hr:152:701942

Jakobović R. Utjecaj specifične profilaktičke terapije migrene na pojavnost nebolnih simptoma migrene bez aure i na kvalitetu života u bolesnika s migrenom [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2024 [cited 2024 November 22] Available at: https://urn.nsk.hr/urn:nbn:hr:152:701942

R. Jakobović, "Utjecaj specifične profilaktičke terapije migrene na pojavnost nebolnih simptoma migrene bez aure i na kvalitetu života u bolesnika s migrenom", Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:152:701942

Metadata
TitleUtjecaj specifične profilaktičke terapije migrene na pojavnost nebolnih simptoma migrene bez aure i na kvalitetu života u bolesnika s migrenom
Title (english)Impact of specific migraine prophylactic therapy on occurrence of non-painful symptoms in migraine without aura and on quality of life in migraine patients
AuthorRužica Jakobović
MentorDavor Jančuljak (mentor)
Committee memberStjepan Jurić (predsjednik povjerenstva)
Committee memberKrunoslav Buljan (član povjerenstva)
Committee memberDavor Jančuljak (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2024-09-20, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract
Cilj istraživanja: Cilj istraživanja je bio ispitati utjecaj primjene specifične profilaktičke terapije u bolesnika s migrenom bez aure na pojavnost nebolnih simptoma migrene: mučnine, povraćanja, fotofobije i fonofobije i ispitati postoji li povezanost učinka specifične profilaktičke terapije migrene na popratne simptome migrene i kvalitete života bolesnika s migrenom bez aure. Nacrt studije: Presječna studija. Ispitanici i metode: U istraživanju je sudjelovalo 28 bolesnika oboljelih od migrene bez aure koji se liječe specifičnim profilaktičkim lijekovima u Ambulanti za glavobolje Klinike za neurologiju KBC-a Osijek. Kao instrument istraživanja su korišteni anonimni anketni upitnik strukturiran za ovo istraživanje, upitnik SF-36 i HIT-6. Rezultati: Primjenom specifičnih profilaktičkih lijekova, 21 (75 %) ispitanik je naveo smanjenje mučnine i/ili povraćanja, 18 (64 %) ispitanika fotofobije i 15 (54 %) ispitanika fonofobije za više od 50 % u odnosu na ranije. Nakon uvođenja specifične profilaktičke terapije, popratni simptomi (mučnina i/ili povraćanje, fotofobija i fonofobija) su u 9 (32 %) ispitanika u manjoj mjeri i u 8 (29 %) ispitanika umjereno utjecali na kvalitetu života i svakodnevno funkcioniranje. Zaključak: Primjenom specifične profilakse, većini ispitanika s migrenom bez aure se značajno smanjila učestalost mučnine i/ili povraćanja, fotofobije i fonofobije u odnosu na ranije. Nakon uvođenja specifične profilakse, popratni simptomi migrene bez aure su umjereno ili u manjoj mjeri utjecali na kvalitetu života i svakodnevno funkcioniranje većine ispitanika.
Abstract (english)
Objective: The objective of the study was to investigate the impact of the usage of specific prophylactic therapy in patients with migraine without aura on the occurrence of non-painful symptoms in migraine: nausea, vomiting, photophobia and phonophobia and to investigate whether there is a connection between the effect of specific prophylactic migraine therapy on accompanying migraine symptoms and the quality of life of patients with migraine without aura. Study Design: Cross-sectional study. Patients and Methods: The study included 28 patients suffering from migraine without aura who were treated with specific prophylactic drugs at the Headache Clinic of the University Hospital Centre Osijek's Neurology Department. An anonymous survey questionnaire structured for this research, the SF-36 and HIT-6 questionnaires were used as research instruments. Results: By using specific prophylactic drugs, 21 (75 %) patientsreported a reduction of nausea and/or vomiting, 18 (64%) patients reduction of photophobia and 15 (54 %) patients reduction of phonophobia by more than 50% compared to before. After the introduction of specific prophylactic therapy, accompanying symptoms (nausea and/or vomiting, photophobia and phonophobia) had a minor impact on the quality of life and daily functioning in 9 (32 %) patients and moderate impact in 8 (29 %) patients. Conclusion: By using specific prophylaxis, the frequency of nausea and/or vomiting, photophobia and phonophobia significantly decreased in the majority of patients with migraine without aura compared to before. After the introduction of specific prophylaxis, the accompanying symptoms of migraine without aura moderately or to a lesser extent affected the quality of life and daily functioning of the majority of patients.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:701942
Study programmeTitle: University Graduate Studies
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-10-29 14:47:45