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undergraduate thesis
Utjecaj kratkotrajnog visokog unosa soli na razinu staničnog oksidativnog stresa kod mononuklearnih stanica periferne krvi Sprague Dawley štakora
Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine, 2015. urn:nbn:hr:152:989005
Planinac, Jovana
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

Institutional repository: Repository of the Faculty of Medicine Osijek

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Planinac, J. (2015). Utjecaj kratkotrajnog visokog unosa soli na razinu staničnog oksidativnog stresa kod mononuklearnih stanica periferne krvi Sprague Dawley štakora (Undergraduate thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:989005

Planinac, Jovana. "Utjecaj kratkotrajnog visokog unosa soli na razinu staničnog oksidativnog stresa kod mononuklearnih stanica periferne krvi Sprague Dawley štakora." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2015. https://urn.nsk.hr/urn:nbn:hr:152:989005

Planinac, Jovana. "Utjecaj kratkotrajnog visokog unosa soli na razinu staničnog oksidativnog stresa kod mononuklearnih stanica periferne krvi Sprague Dawley štakora." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2015. https://urn.nsk.hr/urn:nbn:hr:152:989005

Planinac, J. (2015). 'Utjecaj kratkotrajnog visokog unosa soli na razinu staničnog oksidativnog stresa kod mononuklearnih stanica periferne krvi Sprague Dawley štakora', Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 04 May 2024, https://urn.nsk.hr/urn:nbn:hr:152:989005

Planinac J. Utjecaj kratkotrajnog visokog unosa soli na razinu staničnog oksidativnog stresa kod mononuklearnih stanica periferne krvi Sprague Dawley štakora [Undergraduate thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2015 [cited 2024 May 04] Available at: https://urn.nsk.hr/urn:nbn:hr:152:989005

J. Planinac, "Utjecaj kratkotrajnog visokog unosa soli na razinu staničnog oksidativnog stresa kod mononuklearnih stanica periferne krvi Sprague Dawley štakora", Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2015. Available at: https://urn.nsk.hr/urn:nbn:hr:152:989005

Metadata
TitleUtjecaj kratkotrajnog visokog unosa soli na razinu staničnog oksidativnog stresa kod mononuklearnih stanica periferne krvi Sprague Dawley štakora
Title (english)Effects of short term high salt diet on the cellular oxidative stress in peripheral blood mononuclear cells of Sprague Dawley rats
AuthorJovana Planinac
MentorMartina Mihalj (mentor)
Committee memberInes Drenjančević
Committee memberJasminka Milas-Ahić
Committee memberMartina Mihalj
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2015-11-19, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Medical Biochemistry
Abstract
Povećan unos soli hranom potiskuje renin angiotenzin sustav (RAS) i poznat je čimbenik rizika za razvoj kardiovaskularnih bolesti. Prijašnje studije su pokazale da supresija RAS-a slanom hranom dovodi do poremećene o endotelu ovisne dilatacije zbog povećanog oksidativnog stresa i promjene u stvaranju vazoaktivnih metabolita arahidonske kiseline. U ovom istraživanju smo ispitali pretpostavku da kratkotrajni povećani unos soli dovodi do promjene u antioksidativnom sustavu leukocita što rezultira povećanim stvaranjem slobodnih kisikovih radikala i aktivacijom leukocita. Rezultati istraživanja su potvrdili da kratkotrajna dijeta s povećanim udjelom soli dovodi do porasta oksidativnog stresa u leukocitima iz perifernih limfnih organa, ali ne i do njihove aktivacije.
Abstract (english)
Increased dietary salt suppresses the renin angiotensin system (RAS) and it is a known risk factor for cardiovascular diseases. Recent studies showed that high salt intake-mediated suppression of the RAS leaded to impaired endothelium-dependent dilatation due to increased oxidative stress and changes in the production of vasoactive metabolites of arachidonic acid. Present study examined the hypotesis that short-term increase in salt intake can lead to changes in the antioxidant system of leukocytes, resulting in increased production of oxygen free radicals and leukocyte activation. Our results confirmed increased oxidative stress in leukocytes isolated from peripheral lymphoid organs of animals exposed to high salt diet; however, this did not result in increased leukocyte activation
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:989005
Study programmeTitle: University undergraduate study; specializations in: medical laboratory diagnostics
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni prvostupnik/prvostupnica (baccalaureus/ baccalaurea) medicinske laboratorijske dijagnostike (sveučilišni prvostupnik/prvostupnica (baccalaureus/ baccalaurea) medicinske laboratorijske dijagnostike)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2016-04-11 10:39:12