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undergraduate thesis
Utjecaj kratkotrajne slane dijete na izražajnost HIF1alfa u krvnim žilama štakora
Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine, 2017. urn:nbn:hr:152:936893
Grgić, Karla
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

Institutional repository: Repository of the Faculty of Medicine Osijek

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Grgić, K. (2017). Utjecaj kratkotrajne slane dijete na izražajnost HIF1alfa u krvnim žilama štakora (Undergraduate thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:936893

Grgić, Karla. "Utjecaj kratkotrajne slane dijete na izražajnost HIF1alfa u krvnim žilama štakora." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2017. https://urn.nsk.hr/urn:nbn:hr:152:936893

Grgić, Karla. "Utjecaj kratkotrajne slane dijete na izražajnost HIF1alfa u krvnim žilama štakora." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2017. https://urn.nsk.hr/urn:nbn:hr:152:936893

Grgić, K. (2017). 'Utjecaj kratkotrajne slane dijete na izražajnost HIF1alfa u krvnim žilama štakora', Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 26 November 2024, https://urn.nsk.hr/urn:nbn:hr:152:936893

Grgić K. Utjecaj kratkotrajne slane dijete na izražajnost HIF1alfa u krvnim žilama štakora [Undergraduate thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2017 [cited 2024 November 26] Available at: https://urn.nsk.hr/urn:nbn:hr:152:936893

K. Grgić, "Utjecaj kratkotrajne slane dijete na izražajnost HIF1alfa u krvnim žilama štakora", Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:152:936893

Metadata
TitleUtjecaj kratkotrajne slane dijete na izražajnost HIF1alfa u krvnim žilama štakora
Title (english)The effect of short-term high salt diet on HIF-1alpha expression in the blood vessels of rats
AuthorKarla Grgić
MentorInes Drenjančević (mentor)
Committee memberIvana Jukić (predsjednik povjerenstva)
Committee memberAleksandar Kibel (član povjerenstva)
Committee memberInes Drenjančević (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2017-09-29, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Physiology
Abstract
Cilj: Pomoću odgovarajućeg Western blot protokola, utvrditi razliku u ekspresiji ciljanog proteina HIF-1 alfa u krvnim žilama mozga, između skupine Sprague Dawley štakora na standardnoj dijeti i onih kojima smo povisili udio soli u prehrani. Materijali i metode: Zdravi muški SD štakori starosti 11 tjedana hranjeni su standardnom hranom (0,4% NaCl, CTRL grupa) ili hranom s 4% NaCl (HSD grupa) kroz tjedan dana. U uzorcima krvnih žila mozga western blot metodom, određen je izražaj HIF-1α proteina u uzorcima krvnih žila mozga. Rezultati: Izražaj HIF-1α proteina statistički je značajno povećan (p=0,0031) u HSD skupini u odnosu na CTRL. Zaključak:Visoki unos soli uzrokuje povećanje izražaja HIF-1α proteina u krvnim žilama mozga Sprague-Dawley štakora.
Abstract (english)
Aim: To determine the difference in the feature of the target HIF-1 alpha protein in the brain blood vessels between the group of Sprague Dawley rats on the standard diet and those to which we increased the salt portion in the diet, using the appropriate Western blot protocol. Materials and Methods: Healthy male SD rats, 11 weeks of age, have been fed with standard food (0.4% NaCl, CTRL group) or food with 4% NaCl (HSD group) for a week. The feature of the HIF-1α protein in brain blood vessel samples has been determined by the usage of the Western blot method. Results: The feature of the HIF-1α protein has statistically been significantly increased (p = 0.0031) in the HSD group compared to the CTRL. Conclusion: High salt intake causes the increased feature of the HIF-1α protein in the brain blood vessels of Sprague-Dawley rats.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:936893
Study programmeTitle: University undergraduate study
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni prvostupnik/prvostupnica (baccalaureus/ baccalaurea) medicinske laboratorijske dijagnostike (sveučilišni prvostupnik/prvostupnica (baccalaureus/ baccalaurea) medicinske laboratorijske dijagnostike)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2018-04-24 11:02:06