Abstract | Ciljevi istraživanja: Pratiti liječenje pacijenata od gastritisa u ordinaciji obiteljske medicine tijekom jedne godine (365 dana). Usporediti učestalost posjeta pacijenata liječenih od gastritisa među pacijentima različitih dobnih skupina (35 – 64 godine i 65 i više godina). Utvrditi postoji li korelacija između broja posjeta i kontrole osnovne bolesti (gastritis).
Ispitanici i metode: Podaci o pacijentima uzeti su iz medicinskih dokumentacija ordinacije obiteljske medicine u Splitu. U istraživanje je uključen 151 pacijent kojima je bolest prvi put dijagnosticirana u razdoblju od 2009. do 2017. godine, te se svaki pacijent pratio kroz period od 365 dana od dana same dijagnoze. Nakon prikupljanja podataka, napravljena je analiza u statističkim softwareima SPSS 25 i Statistica 12, a zaključci su doneseni na razini značajnosti od 5%.
Rezultati: Najčešće propisivan lijek kao prva linija terapije bio je ranitidin, odnosno lijekovi iz kategorije antagonista H2 – receptora, dok je ako druga linija terapije najčešće propisivan pantoprazol, odnosno lijekovi inhibitori protonske pumpe (IPP). U sklopu eradikacijske terapije najčešće propisivan IPP bio je pantoprazol, a kao antimikrobni lijek amoksicilin. Najčešća prateća bolest bila je hipertenzija, međutim nije utvrđeno odstupanje od polovice pacijenata (p<0,167). Srednja vrijednost ukupnog broja posjeta bila je značajno veća kod starije dobne skupine (p=0.001). Većina pacijenata je na kraju jednogodišnjeg razdoblja ostala neizliječena (p<0,001), a s obzirom na dobne skupine kojima pripadaju, nije utvrđena statistički značajna razlika u postotku izliječenih pacijenata između te dvije skupine (p=0,850). Neizliječeni pacijenti su imali značajno veći broj posjeta zbog osnovne bolesti (p<0,001), kao i izdvojeni broj posjeta zbog kontrole iste (p<0,001).
Zaključci: Ukupan broj posjeta zbog bilo kakve zdravstvene indikacije bio je veći kod pacijenata starije dobne skupine (65 godina i više), dok kod učestalosti posjeta zbog osnovne bolesti (gastritisa) ili pak zbog kontrole iste, nije pronađena statistički značajna razlika između dviju dobnih skupina.Također, nije pronađena statistički značajna razlika u stopi izlječivosti pacijenata između mlađe i starije dobne skupine, što bi značilo da se kontrola bolesti koja se gleda kroz ishod liječenja nakon jednogodišnjeg perioda, pokazala jednakom kod obje skupine. Utvrđena je korelacija između kontrole bolesti, odnosno ishoda liječenja nakon jednogodišnjeg perioda i broja posjeta, jer su neizliječeni pacijenti imali statistički značajno veći broj posjeta zbog osnovne bolesti, kao i izdvojenih posjeta zbog kontrole iste. |
Abstract (english) | The aims of the search: To follow the treatment of patients diagnozed with gastritis in family physician's office during a period of one year (365 days). To compare the frequency of visits to the physician's office between patients of different age groups ( 35 – 64 years and 65 years and older) and to establish whether there is a correlation between the number of visits and the control over the main disease (gastritits).
Patients and methods: The data were collected from the medical records of a family physician's office in Split. The study involves 151 patient who were diagnozed with gastritis for the first time in the period between 2009 and 2017, and so every patient was monitored during 365 days from the day of the diagnosis. After collecting the data, a statistical analysis was made in statistical softwares SPSS 25 and Statistica 12, and conclusions were made at the significance level of 5%.
Results: The most common drug prescribed as the first line of therapy was ranitidine, respectively the H2 - receptor antagonists, while as the second line of therapy the most commonly prescribed drug was pantoprazole, respectively the proton pump inhibitors (PPIs). Within the eradication therapy the most commonly prescribed PPI was pantoprazole, and as an antimicrobial drug it was amoxicillin. The most common concomitant disease was hypertension, however the deviation from half of the patients involved in the study was not established (p<0,167). The mean value of the total number of visits was significantly higher within the older age group (p=0,001). The majority of patients in this study ended up uncured after the observed one - year period (p<0,001), but looking through the age groups they belong to, there was no significant statistical difference found beetween the groups in the percentage of patients that were successfully cured (p=0,850). Ultimately uncured patients had a significantly higher number of visits because of the main diagnose (p<0,001), and so as the number of the control visits for the same indication (p<0,001).
Conclusions: Total number of visits (for any kind of health indication) was higher within the patients that belong to the older age group (65 years and older), but when it comes to the number of visits because of the main diagnose (gastritis) and the number of control visits due to the same indication, there was no significant difference found between the groups. No significant statistical difference was found between the younger and the older age group in the percentage of cured patients, whiyh means that the control over the main disease which is estimated through the outcome of the treatment after the observed one – year period, turned out to be the same within both age groups. A correlation was established between the control over the main disease, respectively the outcome of the treatment after the observed one – year period and the number of visits, because the uncured patients had statistically significant higher number of visits because of the main disease and number of control visits due to the same indication. |