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master's thesis
Nadoknada tekućine u prvih 48 sati u ozbiljno opečenih bolesnika u odnosu na morbiditet i mortalitet liječenih na JIL-u KBC-a Split u razdoblju od 2015. do 2020.
Split: University of Split, School of Medicine, 2021. urn:nbn:hr:171:921023
Blajić, Ivana
University of Split
School of Medicine
Anesthesiology and intensive medicine

Institutional repository: MEFST Repository

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Blajić, I. (2021). Nadoknada tekućine u prvih 48 sati u ozbiljno opečenih bolesnika u odnosu na morbiditet i mortalitet liječenih na JIL-u KBC-a Split u razdoblju od 2015. do 2020. (Master's thesis). Split: University of Split, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:921023

Blajić, Ivana. "Nadoknada tekućine u prvih 48 sati u ozbiljno opečenih bolesnika u odnosu na morbiditet i mortalitet liječenih na JIL-u KBC-a Split u razdoblju od 2015. do 2020.." Master's thesis, University of Split, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:171:921023

Blajić, Ivana. "Nadoknada tekućine u prvih 48 sati u ozbiljno opečenih bolesnika u odnosu na morbiditet i mortalitet liječenih na JIL-u KBC-a Split u razdoblju od 2015. do 2020.." Master's thesis, University of Split, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:171:921023

Blajić, I. (2021). 'Nadoknada tekućine u prvih 48 sati u ozbiljno opečenih bolesnika u odnosu na morbiditet i mortalitet liječenih na JIL-u KBC-a Split u razdoblju od 2015. do 2020.', Master's thesis, University of Split, School of Medicine, accessed 26 December 2024, https://urn.nsk.hr/urn:nbn:hr:171:921023

Blajić I. Nadoknada tekućine u prvih 48 sati u ozbiljno opečenih bolesnika u odnosu na morbiditet i mortalitet liječenih na JIL-u KBC-a Split u razdoblju od 2015. do 2020. [Master's thesis]. Split: University of Split, School of Medicine; 2021 [cited 2024 December 26] Available at: https://urn.nsk.hr/urn:nbn:hr:171:921023

I. Blajić, "Nadoknada tekućine u prvih 48 sati u ozbiljno opečenih bolesnika u odnosu na morbiditet i mortalitet liječenih na JIL-u KBC-a Split u razdoblju od 2015. do 2020.", Master's thesis, University of Split, School of Medicine, Split, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:171:921023

Metadata
TitleNadoknada tekućine u prvih 48 sati u ozbiljno opečenih bolesnika u odnosu na morbiditet i mortalitet liječenih na JIL-u KBC-a Split u razdoblju od 2015. do 2020.
Title (english)The relation between morbidity and mortality rates and the fluid resuscitation within the first 48 hours in severely burnt ICU patients treated at the University Hospital of Split from 2015 to 2020
AuthorIvana Blajić
MentorMihajlo Lojpur (mentor)
Committee memberSanda Stojanović Stipić (predsjednik povjerenstva)
Committee memberBožidar Duplančić (član povjerenstva)
Committee memberMarino Vilović (član povjerenstva)
GranterUniversity of Split
School of Medicine
(Anesthesiology and intensive medicine)
Split
Defense date and country2021, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Anesthesiology and Reanimatology
Abstract
Ciljevi: Svrha istraživanja bila je utvrditi je li nadoknada kristaloidnih otopina u prva 24 h i koloidnih otopina u sljedeća 24 sata smanjuje smrtnost kod bolesnika s opeklinama te je li ishod liječenja povezan sa spolom, postotkom opečene površine, životnom dobi, komplikacijama opeklina i čimbenicima rizika. Ispitanici i metode: Ovo retrospektivno istraživanje obuhvatilo je 49 bolesnika s opeklinama liječenim na JIL-u KBC-a Split u razdoblju od 1. siječnja 2015. do 31. prosinca 2020. Za svakog bolesnika iz medicinske dokumentacije uzeti su podatci o dobi, spolu, TBSA (%), komplikacijama, količini i vrsti tekućina koje su primili u prvih 48 sati, kao i podatci o diurezi u prva dva dana. Prema formulama izračunate su količine koje su trebali primiti, odnosno izmokriti u prva dva dana liječenja kako bi se navedeni podatci usporedili s ishodom liječenja. Rezultati: Životna dob bolesnika i postotak opečene površine tijela značajno utječu na ishod liječenja. Izgled za smrtni ishod raste 5 puta porastom dobne skupine za 10 godina, dok porastom TBSA za 10 % izgled za isti ishod raste za 2,7 puta. Izračunavanjem postotka primljene količine u odnosu na potrebnu količinu kristaloida u prvih 8 sati i koloida u drugom danu dokazali su veću vjerojatnost preživljenja ukoliko bolesnik primi količinu tekućine prema formuli. Utjecaj spola na ishod liječenja objašnjava se dominacijom žena u starijim dobnim skupinama. Prisutnost većeg broja komplikacija, kao i čimbenika rizika povećavaju vjerojatnost smrtnog ishoda. Zaključci: Istraživanje je pokazalo očekivanu povezanost životne dobi bolesnika i postotka opečene površine s ishodom liječenja. Ovom studijom djelomično smo potvrdili utjecaj primjerene nadoknade tekućine u prvih 48 sati na ishod liječenja opečenih bolesnika. Istraživanje je pokazalo kako veći broj komplikacija i čimbenika rizika povećava izgled za smrtni ishod.
Abstract (english)
Objectives: This research aimed to do two things: the first was to determine whether or not the infusion of crystalloid solutions within the first 24 hours followed by the infusion of colloid solutions within the next 24 hours decreases mortality rate in burn patients; the second, to see whether or not the outcome of the treatment was in any way connected to gender, age, percentage of burnt area, complications caused by the burns and risk factors. Subjects and methods: This retrospective research included the total of 49 burn patients who were treated in the ICU at the University Hospital of Split (Croatia) between the 1st of January 2015 and the 31st of December 2020. Patients were differentiated according to their age, gender, TBSA (%), health complications, type and quantity of fluids administered within the first 48 hours, as well as information on diuresis in the first two days. Specific formulae were used to determine the quantity of fluids that should have been administered and urinated in the first two days so as to compare them to the outcome of the treatment. Results: The research has shown that the patient's age and the percentage of burnt surface of the body influence greatly the outcome of the treatment. The chances of a lethal outcome are 5 times higher in each age group (the span of 10 years was used to determine age groups). The rise of TBSA by only 10% makes the chances of a lethal outcome 2.7 times higher in each age group. A formula was used to calculate the percentage of administered crystalloids within the first 8 hours and colloids in the second day in relation to the quantity necessary to survive. The research has partially proven that the patient's chances of survival grow depending on the percentage of administered fluids. The impact of gender on the outcome of the treatment can be explained by the female domination in older age groups. The presence of a larger number of complications and risk factors both increase the probability of a lethal outcome. Conclusions: This research has shown that the age and the percentage of the burnt surface of the body are connected to the outcome of the treatment. The positive influence of resuscitated fluids within the first 48 hours has been partially confirmed. The research has also shown that a larger number of health complications and risk factors increase the chances of a lethal outcome.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:171:921023
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-07-30 08:31:48