| Abstract | Cilj: Cilj ovog istraživanja je usporediti klinički ishod između različitih skupina životno ugroženih bolesnika s COVID-19 infekcijom.
Materijali i metode: U ovo retrospektivno istraživanje uključeni su pacijenti s COVID-19 infekcijom, koji su liječeni u Jedinici intenzivnog liječenja (JIL-u) u razdoblju od ožujka 2020. do srpnja 2020. godine. Iz arhiva povijesti bolesti prikupljeni su podatci o dobi, spolu, duljini boravka, ishodu, komorbiditetima, razlogu prijema u JIL, razvijenim komplikacijama te primjeni vazopresora.
Rezultati: U ovom istraživanju 55,56% pacijenata su bili muškarci, a 44,44% pacijenata su bile žene. Preživljenje pacijenata u skupini pacijenata koji su imali 2 komorbiditeta bilo je 33,33%, dok je u skupini pacijenata koji nisu imali komorbiditete iznosilo 50% (P=0,497). Preživljenje je bilo 3,5 puta veće u pacijenata koji su primali vazopresore u usporedbi s pacijentima koji ih nisu primali (P=0,003). Pacijenti koji su razvili kao komplikaciju akutno bubrežno zatajenje za 1,1 češće imali su smrtni ishod nego pacijenti koji nisu razvili tu komplikaciju (P=0,824). Srednja vrijednost najvišeg D-dimera bila je za 9,93 mg/L veća u pacijenata koji su preminuli u odnosu na srednju vrijednost u pacijenata koji su preživjeli (P=0,234).
Zaključci: Veće stope smrtnosti bile su prisutne u bolesnika koji su primali vazopresore, koji imaju 2 ili više komorbiditeta, koji su imali visoke vrijednostima D-dimera te u bolesnika koji su kao komplikaciju razvili akutno bubrežno zatajenje. |
| Abstract (english) | Objective: The aim of this study was to compare the clinical outcome between different groups of critically ill COVID-19 patients.
Materials and methods: This retrospective study included patients with COVID-19 infection, who were treated in the Intensive Care Unit between March 2020 and July 2020. Data on age, sex, length of stay, outcome, comorbidities, reason for admission to the ICU, developed complications and use of vasopressors were collected from the medical history archives
Results: In this study, 55.56% of patients were men and 44.44% of patients were women. Survival of patients in the group of patients who had 2 comorbidities was 33.33%, while in the group of patients who did not have comorbidities it was 50% (P=0.497). Survival was 3.5-fold higher in patients receiving vasopressors compared with patients who did not receive them (P=0.003). Patients who developed acute renal failure as a complication were 1.1 times more likely to have a fatal outcome than patients who did not develop this complication (P=0.824). The mean value of the highest D-dimer was 9.93 mg / L higher in patients who died compared to the mean value in patients who survived (P=0.234).
Conclusions: Higher mortality rates were present in patients receiving vasopressors, who had 2 or more comorbidities, who had high D-dimer values, and in patients who developed acute renal failure as a complication. |
