prikaz prve stranice dokumenta Razine 25-hidroksi vitamina D u novootkrivenih pedijatrijskih bolesnika sa šećernom bolesti tipa 1
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master's thesis
Razine 25-hidroksi vitamina D u novootkrivenih pedijatrijskih bolesnika sa šećernom bolesti tipa 1
Split: University of Split, School of Medicine, 2022. urn:nbn:hr:171:698081
Toto, Tina
University of Split
School of Medicine

Institutional repository: MEFST Repository

Cite this document

Toto, T. (2022). Razine 25-hidroksi vitamina D u novootkrivenih pedijatrijskih bolesnika sa šećernom bolesti tipa 1 (Master's thesis). Split: University of Split, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:698081

Toto, Tina. "Razine 25-hidroksi vitamina D u novootkrivenih pedijatrijskih bolesnika sa šećernom bolesti tipa 1." Master's thesis, University of Split, School of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:171:698081

Toto, Tina. "Razine 25-hidroksi vitamina D u novootkrivenih pedijatrijskih bolesnika sa šećernom bolesti tipa 1." Master's thesis, University of Split, School of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:171:698081

Toto, T. (2022). 'Razine 25-hidroksi vitamina D u novootkrivenih pedijatrijskih bolesnika sa šećernom bolesti tipa 1', Master's thesis, University of Split, School of Medicine, accessed 13 March 2025, https://urn.nsk.hr/urn:nbn:hr:171:698081

Toto T. Razine 25-hidroksi vitamina D u novootkrivenih pedijatrijskih bolesnika sa šećernom bolesti tipa 1 [Master's thesis]. Split: University of Split, School of Medicine; 2022 [cited 2025 March 13] Available at: https://urn.nsk.hr/urn:nbn:hr:171:698081

T. Toto, "Razine 25-hidroksi vitamina D u novootkrivenih pedijatrijskih bolesnika sa šećernom bolesti tipa 1", Master's thesis, University of Split, School of Medicine, Split, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:171:698081

Metadata
TitleRazine 25-hidroksi vitamina D u novootkrivenih pedijatrijskih bolesnika sa šećernom bolesti tipa 1
Title (english)25-hydroxyvitamin D levels in newly detected pediatric patients with type 1 diabetes
AuthorTina Toto
MentorMarko Šimunović (mentor)
Committee memberRenata Pecotić (predsjednik povjerenstva)
Committee memberJoško Božić (član povjerenstva)
Committee memberMarino Vilović (član povjerenstva)
GranterUniversity of Split
School of Medicine
Split
Defense date and country2022, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pediatrics
Abstract
Ciljevi: Glavni cilj je bio istražiti povezanost između razina 25-hidroksi vitamina D i stupnja metaboličkog urušaja u novootkrivenih bolesnika s ŠBT1. Ispitanici i postupci: U istraživanje je uključeno 83 djece sa novodijagnosticiranom ŠBT1 koja su primljena na Kliniku za pedijatriju, Zavod za endokrinologiju Kliničkog bolničkog centra Split (KBC Split) u razdoblju od 1. siječnja 2018. do 31. prosinca 2020. godine. Analiza je uključivala anamnezu, klinički pregled, antropometrijska... More mjerenja i uzorkovanje krvi. Rezultati: Utvrđena je statistički značajno niža vrijednost pH (7,42 – 7,05 vs. 7,42 – 7,33; P=0,003) te bikarbonata (22,2 – 3,6 mmol/L vs. 23,5 – 13,3 mmol/L; P=0,002) kod skupine sa koncentracijom 25-hidroksi vitaminom D manjom od 50 nmol/L od skupine sa koncentracijom vitamina D većom od 50 nmol/L te statistički značajna pozitivna korelacija razine pH (r=0,366; P=0,001) kao i koncentracije bikarbonata (r=0,340; P=0,002) sa razinom 25-hidroksi vitamina D. Uz to je utvrđena i statistički značajna negativna korelacija koncentracije ß- hidroksibutirata sa koncentracijom 25-hidroksi vitamina D (r=-0,246; P=0,030). Zaključak: Potvrđena je povezanost između razina 25-hidroksi vitamina D i laboratorijskih parametara pH vrijednosti, bikarbonata i ß- hidrksibutirat koji mogu ukazivati na stupanj metaboličkog urušaja u novootkrivenih bolesnika sa ŠBT1. Less
Abstract (english)
Objectives: The aim of this study was to establish the association between the levels of 25- hydroxyvitamin D and the degree of metabolic collapse in newly diagnosed patients with type 1 diabetes mellitus (T1DM). Subjects and methods: This study enrolled 83 newly T1DM pediatric patients which were admitted to the Division of Pediatric Endocrinology at the University Hospital of Split in the period from January 2018 to December 2020. Evaluation included physical examination, ... More medical history, anthropometric measurement and blood sample. Results: A statistically significantly lower value of pH (7.42 – 7.05 vs. 7.42 – 7.33; P=0.003) and bicarbonate (22.2 – 3.6 mmol/L vs. 23.5 – 13, 3 mmol/L; P=0.002) were found in the group with the concentration of 25-hydroxyvitamin D lower than 50 nmol/L than the group with the concentration of vitamin D higher than 50 nmol/L. In addition, a statistically significant positive correlation was found between the pH level (r=0.366; P= 0.001) as well as the concentration of bicarbonate (r=0.340; P=0.002) and the level of 25-hydroxyvitamin D and a statistically significant negative correlation between the concentration of ß-hydroxybutyrate and the concentration of 25-hydroxyvitamin D (r=-0.246; P =0.030). Conclusion: This study has confirmed the association between the levels of 25-hydroxyvitamin D and the laboratory parameters of pH value, bicarbonate and ß-hydroxybutyrate, which may indicate the degree of metabolic collapse in newly diagnosed patients with T1DM. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:171:698081
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Embargo expiration date: 2022-07-30
Terms of useLicence In copyright icon
Created on2022-07-22 10:43:38
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