Objectives: The aim of this research was to determine the frequency of a positive screening test for sleep apnea (STOP questionnaire) in patients with hidradenitis suppurativa compared to the general population. Patients and methods: An observational, cross-sectional study was conducted involving 40 participants (HS; control group). Participants in the HS group completed a questionnaire about their illness and the STOP questionnaire, while participants in the control group only completed the STOP questionnaire. Collected data included personal information, disease-related data, body measurements, and pain and therapy satisfaction ratings on the NRS scale. Quantitative data were presented using medians. Fisher's exact test was used for comparison of qualitative data, and the Mann-Whitney U test was used for comparison of quantitative variables. Results: Based on the results of the STOP questionnaire analysis, a significantly higher risk for developing OSA was observed in participants with HS compared to the control group; P=0.019. In the HS group, 11 out of 20 (55%) participants had a score ≥ 2, while in the control group, only 3 out of 20 (15%) participants had a score ≥ 2. In the control group, no statistically significant difference was found in the STOP questionnaire score between men and women; P=0.270. In the HS group, only men had a score ≥ 2; P<0.001. The median age of HS participants with a STOP questionnaire score ≥ 2 was 16 years higher than in participants with a score < 2; P=0.003. The median BMI of HS participants was 27.8, and 26.2 in the control group; P=0.036. The hypotheses that higher pain and therapy dissatisfaction contribute to a higher risk for OSA development were not confirmed by this study; P>0.005. Conclusions: Participants with hidradenitis suppurativa have a higher frequency of positive screening test for sleep apnea and a higher BMI compared to the control group. No association was found between pain intensity and satisfaction with biological therapy and a higher frequency of positive screening test (STOP questionnaire) for sleep apnea.