prikaz prve stranice dokumenta Coronary lesion pattern and outcome of elderly and very elderly patients with acute coronary syndrome
  Download
PDF 947.63 KB
master's thesis
Coronary lesion pattern and outcome of elderly and very elderly patients with acute coronary syndrome
Split: University of Split, School of Medicine, 2023. urn:nbn:hr:171:008724
Koc, Yeliz
University of Split
School of Medicine

Institutional repository: MEFST Repository

Cite this document

Koc, Y. (2023). Coronary lesion pattern and outcome of elderly and very elderly patients with acute coronary syndrome (Master's thesis). Split: University of Split, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:008724

Koc, Yeliz. "Coronary lesion pattern and outcome of elderly and very elderly patients with acute coronary syndrome." Master's thesis, University of Split, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:171:008724

Koc, Yeliz. "Coronary lesion pattern and outcome of elderly and very elderly patients with acute coronary syndrome." Master's thesis, University of Split, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:171:008724

Koc, Y. (2023). 'Coronary lesion pattern and outcome of elderly and very elderly patients with acute coronary syndrome', Master's thesis, University of Split, School of Medicine, accessed 27 May 2024, https://urn.nsk.hr/urn:nbn:hr:171:008724

Koc Y. Coronary lesion pattern and outcome of elderly and very elderly patients with acute coronary syndrome [Master's thesis]. Split: University of Split, School of Medicine; 2023 [cited 2024 May 27] Available at: https://urn.nsk.hr/urn:nbn:hr:171:008724

Y. Koc, "Coronary lesion pattern and outcome of elderly and very elderly patients with acute coronary syndrome", Master's thesis, University of Split, School of Medicine, Split, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:171:008724

Metadata
TitleCoronary lesion pattern and outcome of elderly and very elderly patients with acute coronary syndrome
Title (croatian)Uzorak koronarne lezije i ishod kod starijih i vrlo starijih bolesnika s akutnim koronarnim sindromom
AuthorYeliz Koc
MentorChristian Mahnkopf (mentor)
VIAF: 13497582
Committee memberJohannes Brachmann (predsjednik povjerenstva)
Committee memberWalter Ludwig Strohmaier (član povjerenstva)
Committee memberRenata Pecotić (član povjerenstva)
GranterUniversity of Split
School of Medicine
Split
Defense date and country2023-07-24, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
Objectives: The purpose of this study was to compare acute coronary syndrome patients who were old or very old (≥75 years) to younger patients in terms of coronary pathology, comorbidities, coronary intervention, and the short-term outcome following PCI. Materials and Methods: This retrospective monocentric investigation was performed between January 1 and October 1, 2022, and included all patients who were treated invasively for their acute coronary syndrome. Patients were divided into two groups: patients equal to or over 75 years old (elderly group) and patients under 75 years old (young group). We compared risk factors, cardiac and extra comorbidities, ECG, ultrasound, laboratory results, complications after angiography, death and outcome of coronary intervention in these two groups. Results: The final study comprised 101 patients who underwent PCI or coronary angiography as part of their treatment for ACS (29 females (28.7%) and 72 males (71.3%). The age ranged from 41 to 97 years, with a mean age of 69 (±13 years). When compared to the elderly group, the younger group had more patients (63 patients (62.4%) vs. 38 patients (37.6%). Regarding risk factors and comorbidities, there were no significant differences between the groups, except for a significantly higher incidence of CKD in the elderly group. In contrast to the younger group, we found older patients to have more severe CAD. For the treatment of their ACS, more patients in the younger group had stents implanted (56 patients (88.9%) vs. 24 patients (63.2%), P=0.002). Both groups' complications and short-term mortality rates were comparable. Conclusion: Our findings suggest that PCI or coronary angiography is a safe and effective treatment for elderly patients over the age of 75 because complications and mortality are comparable to younger individuals. Since a considerable portion of this vulnerable patient group might be predicted to have positive outcomes from coronary procedures, elderly patients shouldn't be denied access to invasive treatment of their ACS.
Abstract (croatian)
Ciljevi: Svrha ove studije bila je usporediti bolesnike s akutnim koronarnim sindromom koji su bili stari ili vrlo stari (≥75 godina) s mlađim bolesnicima u pogledu koronarne patologije, komorbiditeta, koronarne intervencije i kratkoročnih ishoda nakon PCI postupka. Materijali i metode: Ova retrospektivna monocentrična studija provedena je od 1. siječnja do 1. listopada 2022. godine i uključila je sve bolesnike koji su bili invazivno liječeni zbog svog akutnog koronarnog sindroma. Bolesnici su podijeljeni u dvije skupine: bolesnici koji su stari jednako ili preko 75 godina (starija skupina) i bolesnici mlađi od 75 godina (mlađa skupina). Usporedili smo čimbenike rizika, srčane i dodatne komorbiditete, EKG, ultrazvuk, laboratorijske rezultate, komplikacije nakon angiografije, smrtnost i ishod koronarne intervencije u ovim dvjema skupinama. Rezultati: Završna studija obuhvatila je 101 bolesnika koji su podvrgnuti PCI postupku ili koronarnoj angiografiji kao dio njihovog liječenja za ACS (29 žena (28,7%) i 72 muškarca (71,3%). Dob se kretala od 41 do 97 godina, s prosječnom dobi od 69 (±13 godina). Uspoređujući s starijom skupinom, mlađa skupina imala je više bolesnika (63 bolesnika (62,4%) naspram 38 bolesnika (37,6%). Što se tiče čimbenika rizika i komorbiditeta, nije bilo značajnih razlika između skupina, osim znatno veće učestalosti kronične bolesti bubrega (CKD) u starijoj skupini. Nasuprot mlađoj skupini, primijetili smo da stariji bolesnici imaju teži oblik koronarne arterijske bolesti (CAD). U liječenju njihovog ACS-a, više bolesnika u mlađoj skupini imalo je ugrađene stentove (56 bolesnika (88,9%) naspram 24 bolesnika (63,2%), P=0,002). Komplikacije i stope kratkoročne smrtnosti bile su usporedive u obje skupine. Zaključak: Naši rezultati sugeriraju da je PCI ili koronarna angiografija siguran i učinkovit tretman za starije bolesnike starije od 75 godina jer su komplikacije i smrtnost slični mlađim osobama. Budući da se značajan broj ove ranjive skupine bolesnika može očekivati s pozitivnim ishodom koronarnih postupaka, starijim bolesnicima ne bi trebalo uskratiti pristup invazivnom liječenju njihovog ACS-a.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:171:008724
Study programmeTitle: Medical Studies in English
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-07-14 19:39:45