prikaz prve stranice dokumenta Association of European Union funding for pediatric cancer research on pediatric cancer burden in the European Union
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master's thesis
Association of European Union funding for pediatric cancer research on pediatric cancer burden in the European Union
Split: University of Split, School of Medicine, 2023. urn:nbn:hr:171:410847
Sekulovski, Lydia
University of Split
School of Medicine

Institutional repository: MEFST Repository

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Sekulovski, L. (2023). Association of European Union funding for pediatric cancer research on pediatric cancer burden in the European Union (Master's thesis). Split: University of Split, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:410847

Sekulovski, Lydia. "Association of European Union funding for pediatric cancer research on pediatric cancer burden in the European Union." Master's thesis, University of Split, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:171:410847

Sekulovski, Lydia. "Association of European Union funding for pediatric cancer research on pediatric cancer burden in the European Union." Master's thesis, University of Split, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:171:410847

Sekulovski, L. (2023). 'Association of European Union funding for pediatric cancer research on pediatric cancer burden in the European Union', Master's thesis, University of Split, School of Medicine, accessed 29 April 2024, https://urn.nsk.hr/urn:nbn:hr:171:410847

Sekulovski L. Association of European Union funding for pediatric cancer research on pediatric cancer burden in the European Union [Master's thesis]. Split: University of Split, School of Medicine; 2023 [cited 2024 April 29] Available at: https://urn.nsk.hr/urn:nbn:hr:171:410847

L. Sekulovski, "Association of European Union funding for pediatric cancer research on pediatric cancer burden in the European Union", Master's thesis, University of Split, School of Medicine, Split, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:171:410847

Metadata
TitleAssociation of European Union funding for pediatric cancer research on pediatric cancer burden in the European Union
AuthorLydia Sekulovski
MentorShelly Pranić (mentor)
Committee memberJoško Markić (predsjednik povjerenstva)
Committee memberMarino Vilović (član povjerenstva)
Committee memberIris Jerončić Tomić (član povjerenstva)
GranterUniversity of Split
School of Medicine
Split
Defense date and country2023-09-12, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Public Health and Health Care
Public Health
Abstract
Objectives: To analyze the association of European Union funding for pediatric cancer research on pediatric cancer burden in the European Union. Methods: EU grants awarded for childhood cancer research between January 1, 2011 and December 31, 2019 were selected from CORDIS using MeSH-derived terms and then categorized based on the six cancer categories (leukemia, brain/CNS, Hodgkin lymphoma, non-Hodgkin lymphoma, kidney, and other malignancies). The IHME database was used to derive data on disease burden through disability-adjusted life-years (DALYs) in children ages 0 to 17 years for each category of cancer during the same time period (2011-2019). Nonparametric statistical analysis was performed using Spearman rank correlation and the Kruskal- Wallis H test with Dun-Bonferroni post-hoc tests. Results: From 2011 to 2019, 36 EU grants were selected for pediatric research with a total funding of €87.717.655. The amount of funding allocated to each cancer category had a wide range and a significant difference, with brain and CNS cancer receiving the least (4% of funding). No significant difference was found in DALYs according to cancer type, however, a positive correlation was found between DALYs and EU funding. EU funding not having a relationship with DALYs for childhood cancer suggests gaps in cancer management and a need for re-assessment and reform in the healthcare sector regarding childhood cancer. Conclusion: Despite a positive correlation between EU funding and childhood cancer burden, childhood cancer remains the leading cause of disease-related death in children of the EU over one year old. The lack of a relationship between funding and disease burden indicates persistent inequalities in childhood cancer aspects due to its complex management. Important burdens such as side effects, late outcomes, palliative care, and healthcare access might not be prioritized in the EU’s fight against childhood cancer.
Abstract (croatian)
Ciljevi: Analizirati povezanost novčane potpore Europske unije za istraživanja karcinoma kod djece i utjecaj karcninoma kod djece u Europi. Metode: dodijeljena EU sredstva za istraživanja karcinoma kod djece između 01. siječnja 2011 i 31. prosinca 2019. Izbrana su iz CORDISA uporabom pojmova s MESH stranice. Zatim su kategorizirana prema 6 tipova karcinoma (leukemija, mozak/središnji živčani sustav, hodginov limfom i ne hodginov limfom, bubreg, i drugi maligniteti). IHME baza podataka je upotrijebljena za izvadak podataka o utjecaju bolesti kroz “godine života prilagođene invaliditetu” (DALYs) u rasponu godina od 0 do 17 za svaki tip karcinomatijekom istog perioda (2011-2019). Za neparametarsku statističku analizu korištena je Spaerman vrsta korelacije i Kruskal Wallis H test s Dun- Bonferroni post hoc testom. Rezultati: Od 2011 do 2019, 36 EU novčnih sredstava potpore su izabrani za istraživanje karcninoma kod djece s ukupnim financiranjem od 87,717.655 eura. Svaki iznos financiranja koji je dodijeljen pojedinom tipu karcinoma imao je široki opseg i značajnu statističku razliku. Karcinomi mozga i centralnog živčanog sustava najmanje su financirani (4%). Nije pronađena statistički značajna razlika u DALYs-u s obzirom na tip karcinoma, ali utvđena je pozitivna korelacija između DALYs-a i EU financiranja. Budući da financiranje EU nije imalo povezanosti s DALYs-om za karcinome kod djece, podatak ukazuje na nedostatke u liječenju karcinoma i potrebu za ponovnom procjenom i reformom u sektoru zdravstvene skrbi u svezi s malignim bolestima u dječjoj dobi. Zaključak: Unatoč pozitivnoj korelaciji između financiranja EU i utjecaja karcinoma kod djece, karcinom kod djece ostaje vodeći uzrok smrti djece kada je bolest u pitanju posebno kod europske djece starije od godinu dana. Nedostatak povezanosti financiranja i utjecaja bolesti upućuje na stalne nejednakosti u aspektima karcinoma kod djece zbog kompleksnog vođenja. Važni utjecaji bolesti kao što su nuspojave, kasniji ishodi, palijativna skrb i pristup zdravstvenoj skrbi možda nisu prioritizirane u borbi EU protiv karcinoma kod djece.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:171:410847
Study programmeTitle: Medical Studies in English
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-09-11 06:30:17