Title Karakteristike i terapija hospitaliziranih bolesnika sa šećernom bolešću Title (english) Characteristics and therapy of hospitalised patients with diabetes mellitus Author Pjero Bačić Mentor Tina Tičinović Kurir (mentor)Committee member Mladen Krnić (predsjednik povjerenstva)Committee member Renata Pecotić (član povjerenstva)Committee member Dijana Perković (član povjerenstva)Granter University of Split Defense date and country 2024-07-18, Croatia Scientific / art field, BIOMEDICINE AND HEALTHCARE Abstract Ciljevi: Glavni cilj ovog istraživanja je analizirati karakteristike i terapiju hospitaliziranih bolesnika sa šećernom bolešću u stacionaru Zavoda za endokrinologiju, dijabetes i bolesti metabolizma u KBC Split.
Ispitanici i postupci: U istraživanje je uključeno 40 ispitanika s dijagnozom šećerne bolesti tip 1 i tip 2, starijih od 18 godina koji su hospitalizirani na Zavodu za endokrinologiju, dijabetes i bolesti metabolizma KBC-a Split. Svi podatci o ispitanicima su prikupljeni iz BIS-a. Prikupljeni podatci uključuju informacije o spolu, dobi, ITM-e, HbA1C, prisustvu arterijske hipertenzije, dislipidemije, komplikacija šećerne bolesti, trajanju dijabetesa, uzroku i trajanju hospitalizacije i terapiji.
Rezultati: Infekcije su bile najčešći uzrok hospitalizacije ispitanika (30%). Regulacija šećerne bolesti u hospitaliziranih bolesnika prema prosječnoj koncentraciji HbA1C bila je 9,7%. Kardiovaskularne komplikacije su najčešće kronične komplikacije hospitaliziranih bolesnika sa šećernom bolešću s udjelom 75%, potom bubrežne komplikacije s udjelom 50%. Bolesnici sa trajanjem šećerne bolesti duljim od 5 godina su imali značajno veći udio dijabetičke retinopatije (P=0,023) i polineuropatije (P<0,001) u usporedbi sa skupinom bolesnika sa trajanjem šećerne bolesti kraćim od 5 godina. Inzulinska terapija je najčešća terapija u hospitaliziranih bolesnika sa šećernom bolesti s udjelom od 35%. Bolesnici sa trajanjem šećerne bolesti duljim od 5 godina su imali značajno veći udio terapije sulfonilurejom (P=0,006) i inzulinom (P<0,001) u usporedbi sa skupinom bolesnika sa trajanjem šećerne bolesti kraćim od 5 godina. Svim hospitaliziranim bolesnicima sa šećernom bolesti pri otpustu iz bolnice je promijenjena terapija.
Zaključci: Najveći se udio bolesnika sa šećernom bolešću hospitalizira zbog infekcije. Regulacija šećerne bolesti u hospitaliziranih bolesnika prema prosječnoj koncentraciji HbA1C je loša. Kardiovaskularne komplikacije su najčešće kronične komplikacije hospitaliziranih bolesnika sa šećernom bolešću. Bolesnici sa trajanjem šećerne bolesti duljim od 5 godina su imali značajno veći udio dijabetičke retinopatije i polineuropatije u usporedbi sa skupinom bolesnika sa trajanjem šećerne bolesti kraćim od 5 godina. Inzulinska terapija je najčešća terapija u hospitaliziranih bolesnika sa šećernom bolesti. Bolesnici sa trajanjem šećerne bolesti duljim od 5 godina su imali značajno veći udio terapije sulfonilurejom i inzulinom u usporedbi sa skupinom bolesnika sa trajanjem šećerne bolesti kraćim od 5 godina. Svim hospitaliziranim bolesnicima sa šećernom bolesti pri otpustu iz bolnice je promijenjena terapija.
Abstract (english) Objectives: The main goal of this study was to analyze the characteristics and treatment of hospitalized patients with diabetes in the inpatient department of the Institute of endocrinology, diabetes and metabolic diseases at Split University Hospital Center.
Subjects and methods: The study included 40 subjects with a diagnosis of type 1 or type 2 diabetes, older than 18 years of age, who were hospitalized in the Department of endocrinology, diabetes and metabolic diseases of Split University Hospital Center. All data on the subjects were collected from the BIS. The collected data included information on gender, age, BMI, HbA1C, presence of hypertension, dyslipidemia, diabetes complications, diabetes duration, cause and length of hospitalization, and therapy.
Results: Infections were the most common cause of hospitalization for the subjects (30%). Diabetes control in hospitalized patients according to the average HbA1C concentration was 9.7%. Cardiovascular complications were the most common chronic complications in hospitalized patients with diabetes with a prevalence of 75%, followed by renal complications with a prevalence of 50%. Patients with diabetes duration longer than 5 years had a significantly higher prevalence of diabetic retinopathy (P= 0.023) and polyneuropathy (P < 0.001) compared to the group of patients with diabetes duration less than 5 years. Insulin therapy was the most common therapy in hospitalized patients with diabetes with a prevalence of 35%. Patients with diabetes duration longer than 5 years had a significantly higher prevalence of sulfonylurea therapy (P=0.006) and insulin (P<0.001) compared to the group of patients with diabetes duration less than 5 years. All hospitalized patients with diabetes had their therapy changed upon discharge from the hospital.
Conclusions: The majority of patients with diabetes are hospitalized due to infection. Diabetes control in hospitalized patients according to the average HbA1C concentration is poor. Cardiovascular complications are the most common chronic complications in hospitalized patients with diabetes. Patients with diabetes duration longer than 5 years had a significantly higher prevalence of diabetic retinopathy and polyneuropathy compared to the group of patients with diabetes duration less than 5 years. Insulin therapy is the most common therapy in hospitalized patients with diabetes. Patients with diabetes duration longer than 5 years had a significantly higher prevalence of sulfonylurea therapy and insulin compared to the group of patients with diabetes duration less than 5 years. All hospitalized patients with diabetes had their therapy changed upon discharge from the hospital.
Keywords
šećerna bolest
hospitalizacija
akutne komplikacije
kronične komplikacije
terapija
Keywords (english)
diabetes mellitus
hospitalisation
acute complications
chronic complications
therapy
Language croatian URN:NBN urn:nbn:hr:171:627999 Study programme Title: Medicine Type of resource Text File origin Born digital Access conditions Open access Terms of use Created on 2024-07-18 07:32:38
