| Abstract | Cilj: Istražiti ulogu dobi bolesnica s dijagnozom OSA-e u njihovoj procjeni kvalitete spavanja i prekomjerne dnevne pospanosti.
Ispitanici i postupci: U istraživanju je sudjelovalo ukupno 200 bolesnica s dijagnozom OSA-
e. Sve su bolesnice bile u dobi od 18 do 81 godinu, kojima je napravljena cjelonoćna polisomnografija u Centru za medicinu spavanja. Bolesnice su ispunile PSQI i ESS upitnik.
Rezultati: Pronađena je razlika u trajanju N2 stadija spavanja (P=0,009) između bolesnica s blagom (261,5 ± 61,6 min) i teškom (292,9 ± 64,7 min) OSA-om, udjelu N2 stadija spavanja
(P=0,003) između blage (69,6 ± 10,4%) i umjerene (70,5 ± 8,6%) u odnosu na tešku OSA-u (75,2 ± 12%) i u postotku N3 stadija spavanja (P=0,019) između blage (10,5 ± 7,6%) i teške
(7,2 ± 7,8%) OSA-e. Značajan doprinos učinkovitosti spavanja imale su subjektivna kvaliteta spavanja (β=-0,171, P=0,016) i dnevna pospanost (β=0,223, P=0,002), a težina OSA-e i dob nisu imale značajan doprinos. Dob bolesnica razlikovala se s obzirom na dobru (54,2 ± 14,8 godina) i lošu (59,9 ± 10,1 godina) subjektivnu procjenu kvalitete spavanja. Utvrđeno je da optimalna granična vrijednost dobi od 64 godine života, omogućuje razlikovanje subjektivne kvalitete spavanja u žena s dijagnozom OSA-e. Kraće trajanje REM i nonREM stadija spavanja, kraće ukupno vrijeme spavanja, te veća budnost nakon prvog usnivanja i veća latencija spavanja bile su značajno povezane s većim PSQI rezultatom u skupini s blagom OSA-om. Duže trajanje nonREM stadija spavanja i veće ukupno vrijeme spavanja te kraća latencija spavanja bili su povezani s većom dnevnom pospanosti bolesnica s blagom OSA-om.
Zaključak: Žene oboljele od OSA-e značajno se razlikuju u dobi s obzirom na subjektivnu, ali ne i objektivnu procjenu kvalitete spavanja, a optimalnu graničnu vrijednost predstavlja dob od 64 godine. Bolesnice s blagom OSA-om imaju kraće trajanje N2 stadija spavanja, manji udio N2 stadija spavanja i veći udio N3 stadija spavanja od bolesnica s teškom OSA-om. |
| Abstract (english) | Objectives: To investigate the role of age in female OSA patients in their assessment of sleep quality and excessive daytime sleepiness.
Subjects and methods: The study included a total of 200 female patients diagnosed OSA. All participants were women aged 18 to 81 who underwent whole-night polysomnography in the Center for Sleep Medicine. The participants completed PSQI and ESS questionnaires.
Results: A difference was found in the duration of the N2 sleep stage (P=0.009) between mild (261.5 ± 61.6 min) and severe (292.9 ± 64.7 min) OSA, and in the proportion of N2 sleep stage (P=0.003) between mild (69.6 ± 10.4%) and moderate (70.5 ± 8.6%) compared to severe OSA (75.2 ± 12%). Additionally, difference was found in the percentage of N3 sleep stage (P=0.019) between mild (10.5 ± 7.6%) and severe (7.2 ± 7.8%) OSA. Significant contributions to sleep efficiency were made by subjective sleep quality (β=-0.171, P=0.016) and daytime sleepiness (β=0.223, P=0.002). The age of patients differed based on good (54.2 ± 14.8 years) and poor (59.9 ± 10.1 years) subjective sleep quality. It was determined that the optimal age cutoff value of 64 years enables the distinction of subjective sleep quality in women diagnosed with OSA. Shorter duration of REM sleep and non-REM sleep, shorter total sleep time, greater wakefulness after sleep onset, and longer sleep latency were significantly associated with higher PSQI scores in mild OSA. Longer duration of non-REM sleep, greater total sleep time and shorter sleep latency were associated with greater daytime sleepiness in mild OSA.
Conclusions: Women with OSA differ significantly in age regarding subjective but not objective sleep quality, with the optimal cutoff age being 64 years. Patients with mild OSA have a shorter duration of N2 sleep stage, a smaller proportion of N2 sleep stage, and a greater proportion of N3 sleep stage compared to patients with severe OSA. |
